Results 111 to 120 of about 185,291 (318)

Red Blood Cell Adenylate Energetics Is Related to Endothelial and Microvascular Function in Long COVID

Biomedicines
Adenine nucleotides play a critical role in maintaining essential functions of red blood cells (RBCs), including energy metabolism, redox status, shape fluctuations and RBC-dependent endothelial and microvascular functions.
Marzena Romanowska-Kocejko, Agata Jędrzejewska, Alicja Braczko, Klaudia Stawarska, Oliwia Król, Marika Frańczak, Gabriela Harasim, Ryszard T. Smoleński, Marcin Hellmann, Barbara Kutryb-Zając   +9 more
doaj   +1 more source

Adenine nucleotide carrier protein dysfunction in human disease. [PDF]

IUBMB Life, 2023
Mishra G, Coyne LP, Chen XJ.
europepmc   +1 more source

Thermodynamic and kinetic insights into stop codon recognition by release factor 1. [PDF]

, 2014
Stop codon recognition is a crucial event during translation termination and is performed by class I release factors (RF1 and RF2 in bacterial cells). Recent crystal structures showed that stop codon recognition is achieved mainly through a network of ...
Joseph, Simpson, Mathew, Merrill A, Trappl, Krista   +2 more
core  

An Interpretable SERS–AI Platform for Rapid and Quantitative Diagnosis of Polymicrobial UTIs: Powered by Positively Charged Plasmonic Nanoparticles and Attention‐Based Deep Learning

Advanced Science, EarlyView.
This work introduces a label‐free SERS‐AI platform for rapid and interpretable diagnosis of polymicrobial urinary tract infections. By integrating Au@Ag@bPEI substrates with a CNN‐CBAM model, the system enables accurate bacterial identification and proportion prediction, while highlighting biologically relevant Raman features.
Zhonghua Shen, Linguo Xie, Yuwei Hou, Junjie Liang, Yuchi Jia, Haipeng Zhang, Zhenli Sun, Jingjing Du, Zeying He, Chunyu Liu, Wenjing Liu   +10 more
wiley   +1 more source

The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase

Cancer Cell International, 2012
Background GSAO (4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid) and PENAO (4-(N-(S-penicillaminylacetyl)amino) phenylarsonous acid) are tumour metabolism inhibitors that target adenine nucleotide translocase (ANT) of the inner-mitochondrial ...
Park Danielle, Chiu Joyce, Perrone Gabriel G, Dilda Pierre J, Hogg Philip J   +4 more
doaj   +1 more source

P2 purinoceptors signaling in fibroblasts of rat subcutaneous tissue [PDF]

, 2011
Mestrado em Biologia Molecular e CelularO tecido conjuntivo parece estar envolvido na génese de diversas condições patológicas. O aumento da rigidez do tecido conjuntivo, resultante da fibrose, pode constituir um factor importante no mecanismo patogénico
Reis, Carla Patrícia da Silva e Sousa
core   +1 more source

Comprehensive Measurement of Inter‐Individual Variation in DNA Repair Capacity in Healthy Individuals

Advanced Science, EarlyView.
Susceptibility to the health effects of DNA damage depends on a person's ability to repair DNA damage, but DNA repair has been difficult to measure in populations. A functional assay called FM‐HCR is used to measure DNA repair in 6 major pathways across 56 individuals.
Ting Zhai, Patrizia Mazzucato, Catherine Ricciardi, David C. Christiani, Liming Liang, Leona D. Samson, Isaac A. Chaim, Zachary D. Nagel   +7 more
wiley   +1 more source

p-Adic Modelling of the Genome and the Genetic Code

, 2007
The present paper is devoted to foundations of p-adic modelling in genomics. Considering nucleotides, codons, DNA and RNA sequences, amino acids, and proteins as information systems, we have formulated the corresponding p-adic formalisms for their ...
Dragovich, Alexandra, Dragovich, Branko
core   +1 more source

The Mechanism and Potential Therapeutic Strategies of Vascular Aging

AGING MEDICINE, EarlyView.
The phenotypes of vascular aging vary across different blood vessels. Endothelial dysfunction is observable in the endothelium of all vessels, while vascular structural remodeling primarily occurs in arteries. A decline in organ vascular density mainly affects arterioles, venules, and capillaries, whereas thrombosis predominantly occurs in the ...
Wan‐Zhou Wu, Xuan Wang, Fang‐Fang Wu, Xiao‐Tian Yan, Yong‐Ping Bai   +4 more
wiley   +1 more source

A single nucleotide polymorphism produces different transcription profiles in Campylobacter jejuni’s cysM

Frontiers in Microbiology
A single nucleotide polymorphism (SNP) in the 126 bp untranslated region (UTR) directly upstream of Campylobacter jejuni’s cysM (cysteine synthase) results in significant effects on gene transcription.
Nereus W. Gunther IV, Siddhartha Kanrar, Aisha Abdul-Wakeel, Michael J. McAnulty, John Renye, Joseph Uknalis, Gaylen A. Uhlich   +6 more
doaj   +1 more source