Results 11 to 20 of about 188,713 (272)

Adenine Nucleotide Metabolites in Uremic Erythrocytes as Metabolic Markers of Chronic Kidney Disease in Children. [PDF]

J Clin Med, 2021
Piechowicz J, Gamian A, Zwolińska D, Polak-Jonkisz D.   +3 more
europepmc   +3 more sources

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module [PDF]

Nature Communications, 2020
The mechanism by which adenosine monophosphate modulates dynein ATPase-mediated ciliary and flagellar beating remains obscure. Here the authors identify an axonemal module including cilia and flagella associated protein 45 that supports adenine ...
Gerard W. Dougherty, Katsutoshi Mizuno, Tabea Nöthe-Menchen, Yayoi Ikawa, Karsten Boldt, Asaf Ta-Shma, Isabella Aprea, Katsura Minegishi, Yuan-Ping Pang, Petra Pennekamp, Niki T. Loges, Johanna Raidt, Rim Hjeij, Julia Wallmeier, Huda Mussaffi, Zeev Perles, Orly Elpeleg, Franziska Rabert, Hidetaka Shiratori, Stef J. Letteboer, Nicola Horn, Samuel Young, Timo Strünker, Friederike Stumme, Claudius Werner, Heike Olbrich, Katsuyoshi Takaoka, Takahiro Ide, Wang Kyaw Twan, Luisa Biebach, Jörg Große-Onnebrink, Judith A. Klinkenbusch, Kavita Praveen, Diana C. Bracht, Inga M. Höben, Katrin Junger, Jana Gützlaff, Sandra Cindrić, Micha Aviram, Thomas Kaiser, Yasin Memari, Petras P. Dzeja, Bernd Dworniczak, Marius Ueffing, Ronald Roepman, Kerstin Bartscherer, Nicholas Katsanis, Erica E. Davis, Israel Amirav, Hiroshi Hamada, Heymut Omran   +50 more
doaj   +2 more sources

Adenine Nucleotide Translocase 1 Expression is Coupled to the HSP27-Mediated TLR4 Signaling in Cardiomyocytes. [PDF]

Cells, 2019
The cardiac-specific overexpression of the adenine nucleotide translocase 1 (ANT1) has cardioprotective effects in various experimental heart disease models.
Winter J, Hammer E, Heger J, Schultheiss HP, Rauch U, Landmesser U, Dörner A.   +6 more
europepmc   +4 more sources

Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy. [PDF]

Int J Mol Sci, 2019
Adenine nucleotides (AdNs: ATP, ADP, AMP) are essential biological compounds that facilitate many necessary cellular processes by providing chemical energy, mediating intracellular signaling, and regulating protein metabolism and solubilization.
Miller SG, Hafen PS, Brault JJ.
europepmc   +3 more sources

Brain injury alters ectonucleotidase activities and adenine nucleotide levels in rat serum [PDF]

Journal of Medical Biochemistry, 2015
Background: Cortical stab injury (CSI) induces changes in the activity, expression and cellular distribution of specific ectonucleotidases at the injury site.
Laketa Danijela, Savić Jasmina, Bjelobaba Ivana, Lavrnja Irena, Vasić Vesna, Stojiljković Mirjana, Nedeljković Nadežda   +6 more
doaj   +2 more sources

The essential role of adenine nucleotide translocase 4 on male reproductive function in mice. [PDF]

Braz J Med Biol Res
Yang F, Yang X, Zhu H, Wang X, Liao X, Fu Y, Fu T, Chen X, Sysa A, Lyu J, Zhou H.   +10 more
europepmc   +3 more sources

Site-specific acetylation of adenine nucleotide translocase 1 at lysine 23 in human muscle. [PDF]

Anal Biochem, 2021
Finlayson J, Barakati N, Langlais PR, Funk J, Zapata Bustos R, Coletta DK, Luo M, Willis WT, Mandarino LJ.   +8 more
europepmc   +2 more sources

CoCl₂-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors

Biomedicines, 2022
Chronic hypoxia drives vascular dysfunction by various mechanisms, including changes in mitochondrial respiration. Although endothelial cells (ECs) rely predominantly on glycolysis, hypoxia is known to alter oxidative phosphorylation, promote oxidative ...
Barbara Kutryb-Zajac, Ada Kawecka, Alicja Braczko, Marika Franczak, Ewa M. Slominska, Roberto Giovannoni, Ryszard T. Smolenski   +6 more
doaj   +1 more source

Absence of Ca2+-induced mitochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in C. crangon and P. serratus. [PDF]

PLoS ONE, 2012
Mitochondria from the embryos of brine shrimp (Artemia franciscana) do not undergo Ca(2+)-induced permeability transition in the presence of a profound Ca(2+) uptake capacity. Furthermore, this crustacean is the only organism known to exhibit bongkrekate-
Csaba Konrad, Gergely Kiss, Beata Torocsik, Vera Adam-Vizi, Christos Chinopoulos   +4 more
doaj   +1 more source

Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy. [PDF]

PLoS ONE, 2009
BACKGROUND:The gene for methylthioadenosine phosphorylase (MTAP) lies on 9p21, close to the gene CDKN2A that encodes the tumor suppressor proteins p16 and p14ARF.
Martin Lubin, Adam Lubin
doaj   +1 more source