Results 21 to 30 of about 370,851 (253)

Lack of Association Between Toll-like Receptor 2 Polymorphisms (R753Q and A-16934T) and Atopic Dermatitis in Children from Thrace Region of Turkey

Balkan Medical Journal, 2017
Background: Atopic dermatitis is the most common chronic inflammatory skin disease. A complex interaction of both genetic and environmental factors is thought to contribute to the disease. Aims: To evaluate whether single nucleotide polymorphisms in the
Ceren Can, Mehtap Yazıcıoğlu, Hakan Gürkan, Hilmi Tozkır, Adnan Görgülü, Necdet Hilmi Süt   +5 more
doaj   +1 more source

The Role of Adenine Nucleotide Translocase in the Mitochondrial Permeability Transition

Cells, 2020
The mitochondrial permeability transition, a Ca2+-induced significant increase in permeability of the inner mitochondrial membrane, plays an important role in various pathologies.
Nickolay Brustovetsky
doaj   +1 more source

Growth performance and some related growth genes expression for some native layer and hybrid broiler chicken breeds [PDF]

Benha Veterinary Medical Journal, 2022
This research was carried out to evaluate the difference in the  mRNA  genetic expression of  the  liver genes as  adenine nucleotide translocase (ANT), cytochrome  oxidase subunit III (COX III),  Insulin like growth factor binding protein 2 (IGFBp2) and 
Samar Hosny Baloza, Fatma El-gendy
doaj   +1 more source

Discovery of a natural thiamine adenine nucleotide [PDF]

, 2007
peer reviewedSeveral important cofactors are adenine nucleotides with a vitamin as the catalytic moiety. Here, we report the discovery of the first adenine nucleotide containing vitamin B1: adenosine thiamine triphosphate (AThTP, 1), or thiaminylated ATP.
De Pauw, Edwin, Gabriel Mazzucchelli, Lucien Bettendorff, Marjorie Gangolf, Gangolf, Marjorie, Mazzucchelli, Gabriel, Wins, Pierre, Makarchikov, Alexander F, Bettendorff, Lucien, Angenot, Luc, Frederich, Michel, Edwin De Pauw, Michel Frédérich, Luc Angenot, Pierre Wins, Wirtzfeld, Barbara, Gigliobianco, Tiziana, Alexander F Makarchikov, Barbara Wirtzfeld, Tiziana Gigliobianco   +19 more
core   +1 more source

Adenine Nucleotide Translocase 1 Expression Modulates the Immune Response in Ischemic Hearts

Cells, 2021
Adenine nucleotide translocase 1 (ANT1) transfers ATP and ADP over the mitochondrial inner membrane and thus supplies the cell with energy. This study analyzed the role of ANT1 in the immune response of ischemic heart tissue. Ischemic ANT1 overexpressing
Fatih Yergöz, Julian Friebel, Nicolle Kränkel, Ursula Rauch-Kroehnert, Heinz-Peter Schultheiss, Ulf Landmesser, Andrea Dörner   +6 more
doaj   +1 more source

Moderate exercise training promotes adaptations in coronary blood flow and adenosine production in normotensive rats

Clinics, 2011
OBJECTIVES: Aerobic exercise training prevents cardiovascular risks. Regular exercise promotes functional and structural adaptations that are associated with several cardiovascular benefits. The aim of this study is to investigate the effects of swimming
Fernanda R. Roque, Ursula Paula Renó Soci, Katia De Angelis, Marcele A. Coelho, Cristina R. Furstenau, Dalton V. Vassallo, Maria Claudia Irigoyen, Edilamar M. Oliveira   +7 more
doaj   +1 more source

CRISPR/Cas9-Mediated Adenine Base Editing in Rice Genome

Rice Science, 2019
SUMMARY: Precise base editing is highly desired in plant functional genomic research and crop molecular breeding. In this study, we constructed a rice-codon optimized adenine base editor (ABE)-nCas9 tool that induced targeted A·T to G·C point mutation of
Li Hao, Qin Ruiying, Liu Xiaoshuang, Liao Shengxiang, Xu Rongfang, Yang Jianbo, Wei Pengcheng   +6 more
doaj   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Substrate Nucleotide-Determined Non-Templated Addition of Adenine by Taq DNA Polymerase: Implications for PCR-Based Genotyping and Cloning

BioTechniques, 1996
The Applied Biosystems PRISMTM fluorescence-based genotyping system as well as the Invitrogen TA Cloning® vector system are influenced by the tendency of Taq DNA polymerase to add an adenine nucleotide to the 3′ end of PCR products after extension ...
V.L. Magnuson, D.S. Ally, S.J. Nylund, Z.E. Karanjawala, J.B. Rayman, J.I. Knapp, A.L. Lowe, S. Ghosh, F.S. Collins   +8 more
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source