Results 31 to 40 of about 102,949 (154)
CellsPrevious work has shown that mouse models fed a non-obesogenic high-fat diet have preserved cardiac function and no obesity-associated comorbidities such as diabetes.
Jihad S. Hawi +5 more
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Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance
Nature Communications, 2017 Adenine nucleotide translocase (ANT) 2 promotes ADP/ATP exchange across the mitochondrial inner membrane. Choet al. show that liver specific Ant2 deletion increases uncoupled respiration and protects mice against fatty liver and obesity-induced insulin ...
Joonseok Cho +19 more
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Regulation of Ecto-5´-Nucleotidase by Docosahexaenoic Acid in Human Endothelial Cells
Cellular Physiology and Biochemistry, 2013 Background/Aims: Modulation of extracellular adenine nucleotide and adenosine concentrations is one potential mechanism by which docosahexaenoic acid (DHA) may exert beneficial effects in critically ill patients.
Vu Thi Thom +2 more
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Highly Efficient CRISPR-Mediated Base Editing in Sinorhizobium meliloti
Frontiers in Microbiology, 2021 Rhizobia are widespread gram-negative soil bacteria and indispensable symbiotic partners of leguminous plants that facilitate the most highly efficient biological nitrogen fixation in nature.
Longxiang Wang +6 more
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Antagonism of Morphine Analgesia by Adenine, Adenosine, and Adenine Nucleotides
Experimental Biology and Medicine, 1973 SummaryAntagonism of the antinociceptive action of morphine in mice by prior parenteral administration of cAMP has been confirmed using two additional analgesic testing procedures, the hot-plate test and the stretching test. The analgesia-antagonistic property, however, is not specific for cAMP because it also occurred after pretreatment with compounds
D R, Gourley, S K, Beckner
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PLoS ONE, 2013 Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapeutic agent. Recombinant human Apo2L/TRAIL has been under clinical trials, whereas various kinds of malignant tumors have resistance to Apo2L ...
Masakatsu Oishi +5 more
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Hidden Pool of Cardiac Adenine Nucleotides That Controls Adenosine Production
Pharmaceuticals, 2023 Myocardial ischemic adenosine production decreases in subsequent events that may blunt its protective functions. To test the relation between total or mitochondrial cardiac adenine nucleotide pool (TAN) on the energy status with adenosine production ...
Magdalena A. Zabielska-Kaczorowska +4 more
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Scientific Reports, 2021 All medically important unicellular protozoans cannot synthesize purines de novo and they entirely rely on the purine salvage pathway (PSP) for their nucleotide generation.
Eva Doleželová +6 more
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Binding of adenine nucleotides to mitochondrial membrane [PDF]
FEBS Letters, 1975 It has been reported from different laboratories [l-4] that mitochondria are capable of binding ATP. However the exact magnitude of binding, and the relevance of this process to the mechanism of oxidative phosphorylation are still unknown, due to the extremely low amounts of bound nucleotides, and to some difficulties in carrying out the measurements ...
Alexandre, A. +2 more
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The Scientific World Journal, 2012 L-arginine is conditionally essetcial amino acid, required for normal cell growth, protein synthesis, ammonia detoxification, tissue growth and general performance, proposed in the treatment of men sterility and prevention of male impotence.
G. Kocic +8 more
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