Results 11 to 20 of about 370,851 (253)

Genistein regulates adipogenesis by blocking the function of adenine nucleotide translocase-2 in the mitochondria [PDF]

, 2021
Genistein exerts antiadipogenic effects, but its target molecules remain unclear. Here, we delineated the molecular mechanism underlying the antiadipogenic effect of genistein.
Ikeda, Takahiro, Mitani, Takakazu, Watanabe, Shun, Takahiro Ikeda, Takakazu Mitani, Shun Watanabe   +5 more
core   +1 more source

Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2 [PDF]

, 2021
Brr2 is an essential Ski2-like RNA helicase that exhibits a unique structure among the spliceosomal helicases. Brr2 harbors a catalytically active N-terminal helicase cassette and a structurally similar but enzymatically inactive C-terminal helicase ...
Wahl, M., Absmeier, E., Imhof, P., Burakovskiy, D., Santos, K., Vester, Karen, Absmeier, Eva, Rodnina, M.V., Santos, K.F., Vester, K., Rodnina, M., Ghane, T., Ghane, Tahereh, Milon, Pohl, Wahl, Markus C., Wahl, M.C., Imhof, Petra, Rodnina, Marina V., Burakovskiy, Dmitry, Milon, P., Santos, Karine F., Petra Imhof, Karen Vester, Dmitry Burakovskiy, Pohl Milon, Tahereh Ghane, Markus C. Wahl, Karine F. Santos, Eva Absmeier, Marina V. Rodnina   +29 more
core   +1 more source

Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain [PDF]

, 2010
Divalent cations are important in the folding and stabilization of complex RNA structures. The adenine-sensing riboswitch controls the expression of mRNAs for proteins involved in purine metabolism by directly sensing intracellular adenine levels ...
Wöhnert, Jens, Schwalbe, Harald (Prof. Dr.), Noeske, Jonas   +2 more
core   +1 more source

Adenine Nucleotide and Nicotinamide Adenine Dinucleotide Measurements in Plants [PDF]

Current Protocols in Plant Biology, 2020
AbstractAs the principal co‐factors of many metabolic pathways, the measurement of both adenine nucleotides and nicotinamide adenine dinucleotide provides important information about cellular energy metabolism. However, given their rapid and reversible conversion as well as their relatively low concentration ranges, it is difficult to measure these ...
Zhang, Youjun, Krahnert, Ina, Bolze, Antje, Gibon, Yves, Fernie, Alisdair   +4 more
openaire   +4 more sources

The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]

, 2013
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
Adam-Vizi, Vera, Monika Wysocka-Kapcinska (368157), Christos Chinopoulos (317665), Roza Kucharczyk (141980), Christos Chinopoulos, Cynthia L David, Chinopoulos Christos, Hunt AM, Vekey, Karoly, Beata Torocsik (317661), Hunt Andrea M., Roza Kucharczyk, Karoly Vekey (5656285), Kucharczyk Roza, Wysocka-Kapcinska M, Cynthia L. David, Vera Adam-Vizi (317663), Vékey Károly, Cynthia L. David (461150), Törőcsik Beáta, Ádám Veronika, Monika Wysocka-Kapcinska, Andrea M. Hunt, Wysocka-Kapcinska, Monika, Lilla Turiak, Tsaprailis, George, David Cynthia L., Törőcsik, Beáta, Turiák, Lilla, Tsaprailis George, Andrea M. Hunt (461151), Wysocka-Kapcinska Monika, Beata Torocsik, Vera Adam-Vizi, George Tsaprailis (268492), Ádám, Veronika, Kucharczyk R, Andrea M Hunt, David CL, George Tsaprailis, Tsaprailis G, Chinopoulos, Christos, Turiák Lilla, Hunt, Andrea M., Lilla Turiak (5656282), Kucharczyk, Roza, David, Cynthia L., Karoly Vekey, Adam-Vizi Vera   +48 more
core   +2 more sources

Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone [PDF]

, 2000
We have applied the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens to a cell-free system for the regeneration of the nicotinamide cofactors NAD and NADP in the biological production of the important semisynthetic opiate drug ...
French, C E, Walker, E H, Bruce, N C, Rathbone, D A, Boonstra, B   +4 more
core   +1 more source

Studies on Three Mitochondrial Proteins: The Phosphate and Adenine Nucleotide Inner Membrane Carriers and the Pyruvate Dehydrogenase Complex [PDF]

, 1991
Protein-chemical and immunological studies were carried out on three mitochondrial proteins: the phosphate and adenine nucleotide inner membrane carriers (PTP and ANT), and the pyruvate dehydrogenase multienzyme complex (PDC)
James, Alexander Gordon
core   +4 more sources

Functional expression of human adenine nucleotide translocase 4 in Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2011
The adenine nucleotide translocase (ANT) mediates the exchange of ADP and ATP across the inner mitochondrial membrane. The human genome encodes multiple ANT isoforms that are expressed in a tissue-specific manner.
Takashi Hamazaki, Wai-Yee Leung, Brian D Cain, David A Ostrov, Peter E Thorsness, Naohiro Terada   +5 more
doaj   +1 more source

Adenine nucleotide translocator transports haem precursors into mitochondria.

PLoS ONE, 2008
Haem is a prosthetic group for haem proteins, which play an essential role in oxygen transport, respiration, signal transduction, and detoxification.
Motoki Azuma, Yasuaki Kabe, Chikanori Kuramori, Masao Kondo, Yuki Yamaguchi, Hiroshi Handa   +5 more
doaj   +1 more source

Intracellular ATP influences synaptic plasticity in area CA1 of rat hippocampus via metabolism to adenosine and activity-dependent activation of adenosine A1 receptors [PDF]

, 2011
The extent to which brain slices reflect the energetic status of the in vivo brain has been a subject of debate. We addressed this issue to investigate the recovery of energetic parameters and adenine nucleotides in rat hippocampal slices and the ...
D. Grahame Hardie, Hardie, D. G. (D. Grahame), Naomi Pentland, Simon Hawley, Frenguelli, Bruno, Doney, Alexander S., Pentland, Naomi, Frenguelli, Bruno G., Stephanie zur Nedden, Hawley, Simon, Alexander S. Doney, Bruno G. Frenguelli, Hardie, D. Grahame, Doney, Alexander S.; id_orcid, Zur Nedden, Stephanie   +14 more
core   +1 more source