Results 21 to 30 of about 185,291 (318)

The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]

, 2013
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
A Keller, A Kemp Jr, A Shevchenko, AA Starkov, AL Goldstein, Andrea M. Hunt, B Cooper, B Guerin, B Hoffmann, B Kucejova, Beata Torocsik, C Chinopoulos, C Chinopoulos, C Janke, C Konrad, C Konrad, Christos Chinopoulos, CP Smith, Cynthia L. David, D De Stefani, DJ Pagliarini, F Jiang, G Arselin, G Brandolin, G Szabadkai, G Woldegiorgis, George Tsaprailis, GJ Lauquin, H Aquila, I Amigo, J Clegg, J Laco, J Traba, J Traba, JA Reynolds, JE Kokoszka, Jeffrey L. Brodsky, JJ Lemasters, JK Eng, JM Baughman, K Beyer, Karoly Vekey, KE Kwast, Lilla Turiak, M Bonora, M Klingenberg, M Rak, M Rey, MA Menze, Monika Wysocka-Kapcinska, NL Andon, NN Zheleznova, O Ozohanics, PJ Henderson, R Craig, R Kramer, R Parvin, RA Haworth, RD Gietz, RK Emaus, Roza Kucharczyk, S Cavero, S Manon, S Uribe, SC Hand, T Hamazaki, TM Rickey, UK Laemmli, V Giorgio, Vera Adam-Vizi, WJ Qian, XJ Chen   +71 more
core   +8 more sources

Adenine Nucleotide and Nicotinamide Adenine Dinucleotide Measurements in Plants [PDF]

Current Protocols in Plant Biology, 2020
AbstractAs the principal co‐factors of many metabolic pathways, the measurement of both adenine nucleotides and nicotinamide adenine dinucleotide provides important information about cellular energy metabolism. However, given their rapid and reversible conversion as well as their relatively low concentration ranges, it is difficult to measure these ...
Zhang, Youjun, Krahnert, Ina, Bolze, Antje, Gibon, Yves, Fernie, Alisdair   +4 more
openaire   +5 more sources

Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy. [PDF]

PLoS ONE, 2009
BACKGROUND:The gene for methylthioadenosine phosphorylase (MTAP) lies on 9p21, close to the gene CDKN2A that encodes the tumor suppressor proteins p16 and p14ARF.
Martin Lubin, Adam Lubin
doaj   +1 more source

Functional expression of human adenine nucleotide translocase 4 in Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2011
The adenine nucleotide translocase (ANT) mediates the exchange of ADP and ATP across the inner mitochondrial membrane. The human genome encodes multiple ANT isoforms that are expressed in a tissue-specific manner.
Takashi Hamazaki, Wai-Yee Leung, Brian D Cain, David A Ostrov, Peter E Thorsness, Naohiro Terada   +5 more
doaj   +1 more source

Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons [PDF]

, 2017
Mutations in the gene encoding valosin-containing protein (VCP) lead to multisystem proteinopathies including frontotemporal dementia. We have previously shown that patient-derived VCP mutant fibroblasts exhibit lower mitochondrial membrane potential ...
Abramov, Andrey Y. Abramov, Angelova, Bartolome, Bobba, Brand, Brown, Charles Arber, Ding, Edri, Elisavet Preza, Eva Carro, Fernando Bartolome, Ganote, Henry Houlden, Imamura, Johnson, Kokoszka, Krauss, Ludtmann, Macarena de Vicente, Marthe H.R. Ludtmann, Meyer, Muqit, Nalbandian, Nalbandian, Nalbandian, Okita, Papkovskaia, Plun-Favreau, Schirris, Selina Wray, Shi, Shi, Sonia Gandhi, Sposito, Vallier, Vieira, Weihl, Weinbach, Weydt, Wray, Yin, Zhivotovsky   +43 more
core   +2 more sources

Adenine nucleotide translocator transports haem precursors into mitochondria.

PLoS ONE, 2008
Haem is a prosthetic group for haem proteins, which play an essential role in oxygen transport, respiration, signal transduction, and detoxification.
Motoki Azuma, Yasuaki Kabe, Chikanori Kuramori, Masao Kondo, Yuki Yamaguchi, Hiroshi Handa   +5 more
doaj   +1 more source

The evolution of purinergic receptors involved in recognition of a blood meal by hematophagous insects

Memorias do Instituto Oswaldo Cruz, 1987
Many blood feeders use adenine nucleotides as cues for locating blood meal. Structure-activity relationship of adenine nucleotides as phagostimulants varies between closely-related species of blood feeders. It is suggested that a preexisting diverse pool
Rachel Galun
doaj   +1 more source

DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA. [PDF]

, 2017
Diversity-generating retroelements (DGRs) are molecular evolution machines that facilitate microbial adaptation to environmental changes. Hypervariation occurs via a mutagenic retrotransposition process from a template repeat (TR) to a variable repeat ...
Guo, Huatao, Han, Jin, Heng, Xiao, Lee, William R, Miller, Jeff F, Naorem, Santa S, Wang, Shufang   +6 more
core   +3 more sources

Conformationally Restricted Adenine Nucleotide Analogs in Mitochondrial Adenine Nucleotide Transport

Zeitschrift für Naturforschung C, 1978
Abstract The conformationally restricted adenine nucleotide analogs 8,3′anhydro-8-oxy-9-(β-ᴅ-xylofurano-syl) adenine-5′-O-tri (di) -phosphate (I) , and 8,2′-anhydro-8-oxy-9-(β-ᴅ-arabinofuranosyl) adenine-5′-O-tri (di)-phosphate (II), were prepared chemically as their α-32P-labelled compounds and compared with syn-structured 8-bromo AT(D)
Morio Ikehara, Karl Siegfried, Eckhard Schlimme   +2 more
openaire   +3 more sources

Lack of Association Between Toll-like Receptor 2 Polymorphisms (R753Q and A-16934T) and Atopic Dermatitis in Children from Thrace Region of Turkey

Balkan Medical Journal, 2017
Background: Atopic dermatitis is the most common chronic inflammatory skin disease. A complex interaction of both genetic and environmental factors is thought to contribute to the disease. Aims: To evaluate whether single nucleotide polymorphisms in the
Ceren Can, Mehtap Yazıcıoğlu, Hakan Gürkan, Hilmi Tozkır, Adnan Görgülü, Necdet Hilmi Süt   +5 more
doaj   +1 more source