Results 151 to 160 of about 60,661 (254)

Bi-analyte demonstration of non-resonant, single-molecule SERS with isolated lithographic enhancement structures. [PDF]

Sci Rep
Jin X, Xia H, Brueck SRJ.
europepmc   +1 more source

Enhancing CRISPR‐Cas12a base editing in plants with LbCas12a variants and introns

Journal of Integrative Plant Biology, EarlyView.
Intron optimization of LbCas12a‐RRV improves cytosine and adenine base editing efficiency in plants, supports multiplexed and double‐strand break‐free genome modification, and expands precise genome engineering tools for crop breeding and plant functional research. ABSTRACT Cytosine base editors (CBEs) and adenine base editors (ABEs) are powerful tools
Yanhao Cheng, Gen Li, Man Zhou, Rushil Mandlik, Doris Wang, Yiping Qi   +5 more
wiley   +1 more source

Assessment of miRNAs as transcriptional regulators in respiratory syncytial virus infection through computational analysis and molecular docking studies. [PDF]

PLoS One
Hassan M, Iqbal MS, Yasir M, Chun W, Yaseen Z, Shahzadi S, Peeples ME, Kloczkowski A.   +7 more
europepmc   +1 more source

Optimized TadA‐derived base editors efficiently manipulate mRNA splicing by A‐to‐G and C‐to‐K editing in potato

Journal of Integrative Plant Biology, EarlyView.
Two optimized TadA‐derived base editors efficiently generate diverse splicing variants by targeting specific splice sites in potato. ABSTRACT Pre‐messenger RNA (pre‐mRNA) splicing is a critical mechanism for post‐transcriptional regulation in plants. Through alternative splicing, plants produce diverse transcriptomes and proteomes that finely regulate ...
Kaiyuan Chen, Yan Zhang, Jiuzhou Deng, Lumin Zhang, Huiying Zhou, Yaxin Duan, Enle Xiao, Guangtao Zhu, Chunzhi Zhang   +8 more
wiley   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

NAD⁺ Enhancer Nicotinamide Riboside Alters Extracellular Purine Metabolism in Human Endothelial Cells. [PDF]

Int J Mol Sci
Harasim-Krawcewicz G, Mierzejewska P, Kawecka A, Frańczak MA, Król O, Presler M, Jędrzejewska A, Kutryb-Zając B, Smoleński RT, Słomińska E.   +9 more
europepmc   +1 more source

Adenine Nucleotides in the Regulation of the Coronary Circulation

Japanese Journal of Pharmacology, 1972
S, Imai, Y, Katano
openaire   +2 more sources

Impact of the invasive diatom species Cymbella janischii on riverine microbial biofilm communities and a potential role of bacterially produced zeatin

Journal of Phycology, EarlyView.
Abstract The diatom Cymbella janischii is an invasive species in Japan, causing nuisance blooms by forming thick mats in rivers. To date, there are no documented studies on the microbiome associations in C. janischii mats or the processes that drive bloom formation.
Eldrin D. L. R. Arguelles, Kana Mugikura, Shinya Sato   +2 more
wiley   +1 more source

Mechanistic studies on HNRNPA2B1 suggest binding but not selective recognition of m⁶A. [PDF]

RNA Biol
Park R, Demny M, Miller LG, Pedraza C, Xenophontos X, Hunt RK, Orr AA, Perez LM, Montalbano M, Contreras LM, Tamamis P.   +10 more
europepmc   +1 more source