Results 201 to 210 of about 117,318 (358)

De Novo Synthesis of Myocardial Adenine Nucleotides in the Rat [PDF]

open access: bronze, 1973
Heinz‐Gerd Zimmer   +3 more
openalex   +1 more source

Exploration of Neurodegenerative Diseases Using Long‐Read Sequencing and Optical Genome Mapping Technologies

open access: yesMovement Disorders, EarlyView.
Abstract Genetic factors play a central role in neurodegenerative disorders. Over the past few decades, significant progress has been made in identifying the causative genes of numerous monogenic disorders, largely due to the widespread adoption of next‐generation sequencing (NGS) technologies in both research and clinical settings.
Guillaume Cogan   +4 more
wiley   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury   +2 more
wiley   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

open access: yesNeuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng   +9 more
wiley   +1 more source

Key Considerations on CITE‐Seq for Single‐Cell Multiomics

open access: yesPROTEOMICS, EarlyView.
ABSTRACT CITE‐Seq (Cellular Indexing of Transcriptomes and Epitopes by Sequencing) is an advanced single‐cell sequencing method to profile both gene expression and protein abundance simultaneously in individual cells using single‐cell mRNA sequencing techniques alongside antibody‐derived tags (ADTs), for protein detection.
Hye‐Wong Song   +3 more
wiley   +1 more source

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