Results 201 to 210 of about 644,554 (330)

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou   +4 more
wiley   +1 more source

Extracellular adenine nucleotides modulate cytokine production by human monocyte‐derived dendritic cells: dual effect on IL‐12 and stimulation of IL‐10

open access: yesEuropean Journal of Immunology, 2002
F. Wilkin   +4 more
semanticscholar   +1 more source

Identification and characterization of a cucumber accession resistant to tomato leaf curl New Delhi virus

open access: yesAnnals of Applied Biology, EarlyView.
Tomato leaf curl New Delhi virus (ToLCNDV) causes significant yield and fruit quality losses in cucurbit crops, particularly in the Mediterranean region. We identified a new source of resistance to ToLCNDV in cucumber (accession ABS.PE.045) and mapped resistance to four genomic intervals in chromosomes 1, 2, 6, and 7.
Livia Donaire   +5 more
wiley   +1 more source

Structural Modeling of NTPDase-Substrate Complexes Preserving Catalytic Experimental Features. [PDF]

open access: yesACS Omega
de Moraes JVB   +6 more
europepmc   +1 more source

Anticancer activities of adenine nucleotides in mice are mediated through expansion of erythrocyte ATP pools.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1989
Eliezer Rapaport, James Fontaine
semanticscholar   +1 more source

The Human Cardiac “Age‐OME”: Age‐Specific Changes in Myocardial Molecular Expression

open access: yesAging Cell, EarlyView.
A multi‐omics analysis was performed to uncover the molecular landscape of human cardiac ageing. We report several insights for the first time: a decrease in proteins composing the structural machinery of the heart; a likely compensatory increase in energetic flux and redox reductive capacity; and an increase in lysosomal activity.
Cassandra Malecki   +20 more
wiley   +1 more source

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