Results 221 to 230 of about 644,554 (330)

Crystal structures reveal the distinct features of the 2'-dG-III riboswitch in the purine riboswitch family. [PDF]

Nucleic Acids Res
Chen K, Liao W, Wang J, Ren Y, Lu Z, Peng X, Wang J, Huang L.   +7 more
europepmc   +1 more source

Fluctuations in mitochondrial membrane potential in single isolated brain mitochondria: modulation by adenine nucleotides and Ca2+.

Biophysical Journal, 2004
O. Vergun, I. Reynolds
semanticscholar   +1 more source

Nucleotide Sequencing of DNA: Preliminary Characterization of the Products of Specific Cleavages at Guanine, Cytosine, or Adenine Residues

, 1972
Winston Salser, Kirk E. Fry, Clifford F. Brunk, Raymond Poon   +3 more
openalex   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Influence of Tariquidar, an ABC Transporter Inhibitor, on the Ca²⁺-Dependent Mitochondrial Permeability Transition Pore. [PDF]

Pharmaceuticals (Basel)
Fedotcheva TA, Kruglov AG, Fedotcheva NI.   +2 more
europepmc   +1 more source

Extracellular Adenine Nucleotides Inhibit the Activation of Human CD4+ T Lymphocytes1

Journal of Immunology, 2002
X. Duhant, L. Schandené, C. Bruyns, Nathalie Suarez Gonzalez, M. Goldman, J. Boeynaems, D. Communi   +6 more
semanticscholar   +1 more source

Epigenetic Regulation of G6PD Drives Metabolic Reprogramming in Intrahepatic Cholangiocarcinoma

Cancer Science, EarlyView.
This study reveals that tumor‐specific enhancers drive G6PD overexpression in intrahepatic cholangiocarcinoma (ICC), thereby enhancing pentose phosphate pathway activity, maintaining redox homeostasis, and promoting cell proliferation and chemoresistance.
Yusuke Nakano, Miwa Tanaka, Takeharu Sakamoto, Masahiro Hashimoto, Taro Tobo, Hideyuki Saito, Tadashi Abe, Tomohiko Ikehara, Takashi Ofuchi, Koto Kawata, Takaaki Masuda, Takayuki Ogino, Mamoru Uemura, Hidetoshi Eguchi, Yuichiro Doki, Koshi Mimori   +15 more
wiley   +1 more source

Preliminary analysis of the metabolic and physical activity profiles of mice lacking the slc43a3-encoded equilibrative nucleobase transporter 1. [PDF]

PLoS One
Sayler AL, Hammond JR.
europepmc   +1 more source

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

Cell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, Yang Liu, Lifang Li, Xiuju Chen, Yueguo Li   +13 more
wiley   +1 more source