Results 221 to 230 of about 117,318 (358)

Rapid and Sensitive Detection of RNA Viruses through Imaging of Marker Molecules Derived from Designed Circular DNA Probes

open access: yesSmall Methods, EarlyView.
This study presents a rapid and sensitive virus detection method that employs imaging of virus‐specific DNA markers. Utilizing specially designed single‐stranded circular DNA probes, this method captures RNA fragments from RNase‐digested viral genomes during the reverse transcriptase‐based reaction, resulting in double‐stranded markers that are ...
Yoon‐ha Jang   +13 more
wiley   +1 more source

Navigating Past Oceans: Comparing Metabarcoding and Metagenomics of Marine Ancient Sediment Environmental DNA

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT The condition of ancient marine ecosystems provides context for contemporary biodiversity changes in human‐impacted oceans. Sequencing sedimentary ancient DNA (sedaDNA) is an emerging method for generating high‐resolution biodiversity time‐series data, offering insights into past ecosystems.
Luke E. Holman   +8 more
wiley   +1 more source

Ancient Microbiomes as Mirrored by DNA Extracted From Century‐Old Herbarium Plants and Associated Soil

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Numerous specimens stored in natural history collections have been involuntarily preserved together with their associated microbiomes. We propose exploiting century‐old soils occasionally found on the roots of herbarium plants to assess the diversity of ancient soil microbial communities originally associated with these plants.
Gianluca Grasso   +7 more
wiley   +1 more source

Independent Avian Epigenetic Clocks for Ageing and Development

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Information on individual age is a fundamental aspect in many ecological and evolutionary studies. However, accurate and non‐lethal methods that can be applied to estimate the age of wild animals are often absent. Furthermore, since the process of ageing is accompanied by a physical decline and the deterioration of biological functions, the ...
Ayke Haller   +3 more
wiley   +1 more source

The Mitochondria‐Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age

open access: yesAging Cell, EarlyView.
The effects of the mitochondria‐targeted peptide therapeutic elamipretide on age‐related muscle function were compared with its effects on molecular biomarkers of aging. It was found that elamipretide treatment partially reverses age‐related cardiac dysfunction and skeletal muscle weakness in mice without significantly affecting muscle epigenetic or ...
Wayne Mitchell   +5 more
wiley   +1 more source

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