Results 171 to 180 of about 74,668 (263)

My Pathway to Adeno-Associated Virus and Adeno-Associated Virus Gene Therapy: A Personal Perspective

Human Gene Therapy, 2020
openaire   +2 more sources

An Improved Method for Determining the Infection Titer of Replication-Competent Adeno-Associated Virus. [PDF]

Biomedicines
Fu J, Yu L, Fu Z, Wang G, Liang C, Shi X, Zhang Y.   +6 more
europepmc   +1 more source

Aquaporin-1 gene therapy as a novel method to treat radiation-induced salivary gland damage: The case for adeno-associated virus vectors. [PDF]

Oral Oncol
Atyeo N, Warner B, Chiorini JA.
europepmc   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Factors impacting protective immunity conferred by vaccination with adeno-associated virus-like particles displaying human papillomavirus L2 residues 17-36. [PDF]

J Virol
Alvarez J, Olczak P, Tsai H-L, Terrell J, Wong M, Tsingine H, Palande V, Prangsgaard J, Huus E, Műller M, Nieland JDV, Roden RBS.   +11 more
europepmc   +1 more source

Early Synovial Regulatory T Cell Engagement in Posttraumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early postinjury biologic processes within the synovium shape disease trajectories. We investigated whether synovial Treg cells are engaged during the early phase following joint injury and whether experimental enrichment of this ...
Xueyou Zhang, Mingde Cao, Jianting Li, Bruma Sai‐Chuen Fu, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung   +5 more
wiley   +1 more source

Characterization of adeno-associated virus binding to alginate and its controlled release. [PDF]

Nanoscale Adv
Amante JJ, Mandeville JR, Hargrove H, Zhang XF, Kearney CJ.   +4 more
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Trends in the Engineering of Adeno-Associated Virus (AAV) for Precision Gene Delivery to the Central Nervous System (CNS). [PDF]

Int J Mol Sci
Oloruntimehin S, Malogolovkin A.
europepmc   +1 more source