Results 181 to 190 of about 110,545 (302)

Systemic MV Gene Therapy Close to Clinical Trials for Several Neuromuscular Diseases [PDF]

Wells, D J
core   +1 more source

RBMX Transcriptionally Repressed by EZH2‐Associated H3K27me3 Modification Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury via Regulating SIRT3/NLRP3 Inflammasome Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ischemic reperfusion injury (IRI) to kidney is a significant clinical factor in acute kidney injury (AKI). This study aimed to investigate the new role of RNA‐binding motif protein X‐linked (RBMX), a modulator of m6A methylation, in renal IRI and to examine the associated regulatory mechanisms. An in vitro renal IRI model was established using
Yi‐Han Wang, Yan Teng, Fang‐Lan Yao, Shu‐Qi Wei, Yan Li   +4 more
wiley   +1 more source

Identification of Recombinant Adeno-Associated Virus Serotypes by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. [PDF]

Anal Chem
Nakatsuka R, Matsumoto K, Liu Y, Takeda K, Tsunaka Y, Torisu T, Yamaguchi Y, Uchiyama S.   +7 more
europepmc   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu, Xi‐Xi Chen, Gui‐Hua Wei, Feng Li, Hai‐Yan Zong   +4 more
wiley   +1 more source

Adeno-Associated Virus Vectors for Therapeutic Gene Transfer

BioTechniques, 2003
Jackie L. Stilwell, R. Jude Samulski
doaj   +1 more source

Quantitative Analysis and Predictive Modeling of Nonspecific Adsorption of Recombinant Adeno-Associated Virus onto Solid Surfaces. [PDF]

Langmuir
Ueda Y, Shibuya R, Shibata K, Murai A, Tsunaka Y, Fukuhara M, Uchiyama S.   +6 more
europepmc   +1 more source

AAV9-TAZ gene replacement ameliorates cardiac TMT proteomic profiles in a mouse model of Barth syndrome [PDF]

, 2019
Byrne, Barry J., Cade, W. Todd, Kang, Peter B., Pacak, Christina A., Saha, Madhurima, Soustek, Meghan S., Suzuki-Hatano, Silveli   +6 more
core   +2 more sources

Adeno-Associated Virus (AAV) [PDF]

, 2008
openaire   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

Adeno-associated virus delivery of anti-alpha toxin monoclonal antibodies confers protection against Staphylococcus aureus infections. [PDF]

PLoS Pathog
Hommes JW, Hughes ME, Cheung D, Petri B, Orthner LM, van der Linden TJ, Bardoel BW, Deo SK, Patel DT, Flannagan RS, Heinrichs DE, Wootton SK, Surewaard BGJ.   +12 more
europepmc   +1 more source