Results 301 to 310 of about 396,665 (375)

Binding sites for adeno-associated virus Rep proteins within the human genome

, 1997
R S Wonderling, R. A. Owens
openalex   +1 more source

Adeno‐associated virus–delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model

Annals of Neurology, 2016
Lorelei Stoica, Sophia H. Todeasa, G. Cabrera, J. Salameh, M. ElMallah, C. Mueller, Robert H. Brown, M. Sena-Esteves   +7 more
semanticscholar   +1 more source

Combination of hydrophilic interaction liquid chromatography and top-down mass spectrometry for characterisation of adeno-associated virus capsid proteins. [PDF]

Anal Bioanal Chem
Beaumal C, Guapo F, Smith J, Carillo S, Bones J.   +4 more
europepmc   +1 more source

The Rep68 Protein of Adeno-Associated Virus Type 2 Increases RNA Levels from the Human Cytomegalovirus Major Immediate Early Promoter

, 1997
R S Wonderling, S R Kyöstió, Scotty La Sherman Walker, R. A. Owens   +3 more
openalex   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Adeno-associated virus 2 CRISPR/Cas9-mediated targeting of hepatitis B virus in tree shrews. [PDF]

Virus Res
Rashid MHO, Kayesh MEH, Hashem MA, Hifumi T, Ogawa S, Miyoshi N, Tanaka Y, Kohara M, Tsukiyama-Kohara K.   +8 more
europepmc   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Degradation and stable maintenance of adeno-associated virus inverted terminal repeats in E. coli. [PDF]

Nucleic Acids Res
Radukic MT, Le DT, Krassuski T, Borchert P, Leach DRF, Müller KM.   +5 more
europepmc   +1 more source

High Efficiency Genomic Transduction of Intact Pancreatic Islets In Long Term Culture with Recombinant Adeno-Associated Virus Vectors (rAAV)

, 1999
Geoffrey D. Block, David J. Kaczorowski
openalex   +1 more source

Capture of adeno‐associated viruses from clarified lysate by continuous flow ultracentrifugation: a comparative study of iodixanol and sucrose gradients

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Adeno‐Associated Virus vectors are widely used in gene therapy due to their safety and efficacy. Despite the interest in their therapeutical application, AAV purification remains a significant challenge. Density gradient ultracentrifugation using cesium chloride, sucrose, or iodixanol gradients are common methods for AAV ...
Sabrina Leigheb, Maral Rahimzadeh, Nikolaus Virgolini, Aida Tleuova, Mahbod Mousavian, Astrid Dürauer, Patricia Pereira Aguilar   +6 more
wiley   +1 more source