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Goose Parvovirus—An Autonomous Member of the Dependovirus Genus?
Virology, 1995 Goose parvovirus is the etiological agent of Derzsy's disease, a fatal hepatitis of young geese. The virus infects geese and Muscovy ducks and can be propagated in the laboratory in primary embryonic goose fibroblasts. To date the virus has only been classified by morphological, biochemical, and culture characteristics as an autonomous parvovirus.
Brown, Kevin E. +2 more
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Molecular Therapy: Methods & Clinical Development, 2021 Most gene therapy clinical trials that systemically administered adeno-associated virus (AAV) vector enrolled only patients without anti-AAV-neutralizing antibodies.
Nemekhbayar Baatartsogt +6 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2022 Adeno-associated virus (AAV) vectors are promising modalities of gene therapy to address unmet medical needs. However, anti-AAV neutralizing antibodies (NAbs) hamper the vector-mediated therapeutic effect.
Yuji Kashiwakura +29 more
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Astrovirus Outbreak in an Animal Shelter Associated With Feline Vomiting
Frontiers in Veterinary Science, 2021 An outbreak of cat vomiting was observed in an animal shelter. Testing for known enteric feline pathogens did not identify a causative agent. Viral metagenomics on four mini pools of feces from cases and controls housed in the same area revealed the ...
Yanpeng Li +8 more
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Coinfection of a Bearded Dragon,Pogona vitticeps, with Adenovirus- and Dependovirus-like Viruses [PDF]
Veterinary Pathology, 1996 Four neonate bearded dragons, Pogona vitticeps, from two collections became ill and died. Multiple tissues were collected and processed for light microscopy. In hematoxylin and eosin-stained sections of liver of one lizard, numerous basophilic intranuclear inclusions were observed.
E R, Jacobson +3 more
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Gene therapy in neuromuscular disorders
Arquivos de Neuro-Psiquiatria, 2022 Monogenic neuromuscular disorders are potentially treatable through gene therapy. Using viral vectors, a therapeutic transgene aims to restore normal levels of a protein not produced by the defective gene, or to silence a gene whose expression leads to ...
Rodrigo Holanda Mendonça +1 more
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Functional roles of the membrane-associated AAV protein MAAP
Scientific Reports, 2021 With a limited coding capacity of 4.7 kb, adeno-associated virus (AAV) genome has evolved over-lapping genes to maximise the usage of its genome. An example is the recently found ORF in the cap gene, encoding membrane-associated accessory protein (MAAP),
Lionel Galibert +13 more
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The Expression Strategy of Goose Parvovirus Exhibits Features of both the Dependovirus and Parvovirus Genera [PDF]
Journal of Virology, 2005 ABSTRACT The RNA transcription profile of the goose parvovirus (GPV) was determined, and it is a surprising hybrid of features of the Parvovirus and Dependovirus genera of the Parvovirinae subfamily of the Parvoviridae . Similar to the
Jianming, Qiu +4 more
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Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. [PDF]
PLoS ONE, 2017 As their names imply, parvoviruses of the genus Dependovirus rely for their efficient replication on the concurrent presence of a helpervirus, such as herpesvirus, adenovirus, or papilloma virus.
Michael Seyffert +9 more
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An Outbreak of Adenoviral Infection in Inland Bearded Dragons (Pogona Vitticeps) Coinfected with Dependovirus and Coccidial Protozoa (IsosporaSp.) [PDF]
Journal of Veterinary Diagnostic Investigation, 2002 Thirty of 200 (15%) hatchling inland bearded dragons were found dead after a short period (48 hours) of weakness and lethargy. The most common clinical signs were head tilt and circling. Six bearded dragons with neurological signs were euthanized, and postmortem examination revealed no gross abnormalities.
Dae Young, Kim +4 more
openaire +2 more sources