Results 41 to 50 of about 6,474 (125)

Structure of the NS1 Protein N-Terminal Origin Recognition/Nickase Domain from the Emerging Human Bocavirus [PDF]

, 2013
This is the publisher's version, also available electronically from http://www.asm.org/Human bocavirus is a newly identified, globally prevalent, parvovirus that is associated with respiratory infection in infants and young children.
Shen, Weiran, Qiu, Jianming, Zhao, Haiyan, Tewary, Sunil Kumar, Tang, Liang   +4 more
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Gene transfer in skeletal and cardiac muscle using recombinant adeno-associated virus

, 2013
Adeno-associated virus (AAV) is a DNA virus with a small ( approximately 4.7 kb) single-stranded genome. It is a naturally replication-defective parvovirus of the dependovirus group.
Bish, Lawrence T., Flotte, Terence R., Gao, Guangping, Mueller, Christian, Gruntman, Alisha M, Sweeney, H. Lee   +5 more
core   +1 more source

Adeno-Associated Virus Activates an Innate Immune Response in Normal Human Cells but Not in Osteosarcoma Cells

, 2011
Adeno-associated virus (AAV) is a small, DNA-containing dependovirus with promising potential as a gene delivery vehicle. Given the variety of applications of AAV-based vectors in the treatment of genetic disorders, numerous studies have focused on the ...
Peter Beard, Beard, Peter, Laredj, Leila N., Leila N. Laredj   +3 more
core   +1 more source

Promyelocytic Leukemia Protein Is a Cell-Intrinsic Factor Inhibiting Parvovirus DNA Replication [PDF]

, 2014
Tripartite motif proteins are important viral restriction factors and affect processes ranging from uncoating to transcription to immune signaling. Specifically, the promyelocytic leukemia protein (TRIM19; also called PML) is a viral restriction factor ...
Hirsch, Matthew L., Jude Samulski, R., Li, Chengwen, Mitchell, Angela M.   +3 more
core   +1 more source

Whole-genome sequencing of parvoviruses from wild and domestic animals in Brazil provides new insights into parvovirus distribution and diversity

, 2018
:Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified.
Tatiana Lopes Ometto, Luiz Tadeu Moraes Figueiredo, Edison Luiz Durigon, Márcio Roberto Teixeira Nunes, Felipe Gonçalves Motta Maia, William Marciel de Souza, Sejal Modha, Robert James Gifford, Luiz Carlos Vieira, Gilberto Sabino-Santos, Adriano de Oliveira Torres Carrasco, Marilia Farignoli Romeiro, Jansen de Araujo, Luzia Helena Queiroz, Marcílio Jorge Fumagalli, Gustavo Olszanski Acrani, Tristan Philip Wesley Dennis   +16 more
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Engineered Replicases, Synthetic DNA, and Long-Read Sequencing Quality Control for Adeno-Associated Virus Production

, 2022
Radukic M. Engineered Replicases, Synthetic DNA, and Long-Read Sequencing Quality Control for Adeno-Associated Virus Production. Bielefeld: Universität Bielefeld; 2022.In gene therapy, diseases can be treated with modified (recombinant) viruses that ...
Radukic, Marco
core   +1 more source

Persistente Infektion bei Leukozyten von Blutspendern und immunsupprimierten Patienten [PDF]

, 2017
Adeno-associated virus (AAV) is ubiquitous but has not so far been associated with human disease. As a dependovirus, it has a biphasic AAV life cycle with latency phase and helper virus-induced productive replication phase.
Khalid, Dina
core   +1 more source

Cell Rep [PDF]

Adeno-associated virus (AAV) vectors have emerged as a gene-delivery platform with demonstrated safety and efficacy in a handful of clinical trials for monogenic disorders.

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Kígyó-adeno- és parvovírus teljes genomjának szekvenciája és analízise, minkét víruscsaládban az első molekuláris elemzések hüllő-eredetű izolátummal [PDF]

, 2005
Doktori tanulmányaim kezdetekor célkitűzésem egy kígyó-eredetű adenovírus izolátum DNS-ének szekvencia-szintű meghatározása és részletes elemzése volt. A témaválasztást alapvetően meghatározták a Ph.D.
Farkas, Szilvia
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Adeno-associated virus (AAV)-3-based vectors transduce haematopoietic cells not susceptible to transduction with AAV-2-based vectors

, 2000
Although adeno-associated virus (AAV)-2 has a broad tissue-host range and can transduce a wide variety of tissue type, some cells, such as erythro-megakaryoblastoid cells, are non-permissive and appear to lack the AAV-2 receptor. However, limited studies
Muramatsu, S-I, Brown, KE, Mizukami, H, Muramatsu, S, Handa, A, Qiu, J   +5 more
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