Results 51 to 60 of about 6,474 (125)

Molecular studies towards gene therapy of chronic granulomatous disease

, 1995
Chronic granulomatous disease (CGD) is human disorder arising from heterogeneous molecular lesions in the genes encoding a phagocyte specific enzyme system, the NADPH-oxidase.
Thrasher, Adrian James
core  

Investigating recombinant AAV (rAAV) gene therapy viral vector production

Gene therapy is a therapeutic approach used to treat diseases by correcting an underlying genetic abnormality. Viral vector systems account for more than 70% of gene therapy delivery vehicles, with the Adeno-Associated Virus (AAV) system the most widely ...
Pidlisna, Kseniia
core   +1 more source

Detection and analysis of emerging porcine parvovirus infections in a swine herd

, 2012
Az állatfajok széles köréből mutathatóak ki parvovírusok. Ezek közülük számos fertőzés klinikai tünetekben is megnyilvánul, de a parvovírusoknak a nagy része szubklinikai, vagy tünetmentes fertőzés formájában mutatható ki.
Horváth, Emőke
core  

Evolutionary Analysis Reveals a Single Amino Acid in the AAV Entry Receptor (AAVR) of Cats That Disrupts Binding of a Major Phylogenetic Group of AAVs. [PDF]

Viruses
Large EE, Mensah I, Kumi G, Chapman MS.
europepmc   +1 more source

Analysis of factors that affect parvovirus expression

, 2005
The positions of sequences necessary for transcription from the promoter located at map unit 4 of the bovine parvovirus (BPV) genome were determined. The autonomous parvoviruses, of which BPV is a member, contain two transcriptional units with promoters ...
Braddon, Virginia Rendall
core  

Gene Therapy Using Recombinant Adeno-Associated Virus for Leber Congenital Amaurosis Induced by RPE65 Mutation. [PDF]

Clin Ophthalmol
Owliaee I, Teimoori A, Shoushtari M, Shojaeian A.   +3 more
europepmc   +1 more source

Aquaporin-1 gene therapy as a novel method to treat radiation-induced salivary gland damage: The case for adeno-associated virus vectors. [PDF]

Oral Oncol
Atyeo N, Warner B, Chiorini JA.
europepmc   +1 more source

98. Characterisation of a Unique Adeno-Associated Virus Forming a New Clade within the Dependovirus Genus

Molecular Therapy, 2009
openaire   +1 more source

Adeno-Associated Virus Gene Therapy for Spinal Muscular Atrophy Induces Hepatotoxicity via Cytokine and Macrophage Activation. [PDF]

Liver Int
Sakai A, Sugiyama M, Onodera M, Fukushima F, Tanaka M, Uchiyama T, Mizokami M, Sumazaki R.   +7 more
europepmc   +1 more source

Terminal glucose as a receptor for adeno-associated virus 44.9. [PDF]

J Virol
Di Pasquale G, Tehrani H, Shinder I, Afione S, Chiorini JA.   +4 more
europepmc   +1 more source