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Biotechnology Journal, Volume 16, Issue 4, April 2021., 2021 This review focus on the advancements of the molecular design of baculovirus vectors for high yield production of adeno‐associated virus (AAV) vectors for gene delivery describing the different generation of expression vectors with associated advantages and critical limitations.
Pranav R.H. Joshi +3 more
wiley +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2008 Introducción. La mucopolisacaridosis IV A (Morquio A) es una enfermedad de depósito lisosómico causada por la deficiencia en la actividad de la enzima N-acetil-galactosamina- 6-sulfato-sulfatasa que produce la acumulación intralisosómica de queratán y ...
Luis Alejandro Barrera +6 more
doaj +1 more source
Parvovirus-derived endogenous viral elements in two South American rodent genomes [PDF]
, 2014 We describe endogenous viral elements (EVEs) derived from parvoviruses (family <i>Parvoviridae</i>) in the long-tailed chinchilla (<i>Chinchilla lanigera</i>) and degu (<i>Octodon degus</i>) genomes.
Arriagada, Gloria, Gifford, Robert J.
core +1 more source
A parvovirus isolated from royal python (Python regius) is a member of the genus Dependovirus
Journal of General Virology, 2004 Parvoviruses were isolated from Python regius and Boa constrictor snakes and propagated in viper heart (VH-2) and iguana heart (IgH-2) cells. The full-length genome of a snake parvovirus was cloned and both strands were sequenced. The organization of the 4432-nt-long genome was found to be typical of parvoviruses.
Szilvia L, Farkas +5 more
openaire +2 more sources
Discovery and characterization of mammalian endogenous parvoviruses [PDF]
, 2010 Public databases of nucleotide sequences contain exponentially increasing amounts of sequence data from mammalian genomes. Through the use of large-scale bioinformatic screening for sequences homologous to exogenous mammalian viruses, we found several ...
Kapoor, A. +5 more
core +1 more source
Detection and Genetic Analysis of Porcine Bocavirus in Different Swine Herds in North Central China
The Scientific World Journal, Volume 2014, Issue 1, 2014., 2014 Porcine Bocavirus (PBoV) has been reported to be associated with postweaning multisystemic wasting syndrome and pneumonia in pigs. In this study, a survey was conducted to evaluate the prevalence of PBoV in slaughter pigs, sick pigs, asymptomatic pigs and classical swine fever virus (CSFV) eradication plan herds in five provinces of China (Henan ...
Mengmeng Liu +7 more
wiley +1 more source
A Comparative Analysis of the Structural Architecture of ssDNA Viruses
Computational and Mathematical Methods in Medicine, Volume 9, Issue 34, Page 183-196, 2008., 2008 Virus assembly, utilizing a limited number of viral coat protein (CP or VP) building blocks, is an excellent example of a directed macromolecular interaction occurring in nature. Two basic principles govern the assembly of spherical (icosahedral) viruses: (i) Genetic Economy – the encapsidated genome encodes a single or few CPs that assemble a ...
Antonette Bennett +2 more
wiley +1 more source
Parvovirus B‐19 Infection During Pregnancy
Infectious Diseases in Obstetrics and Gynecology, Volume 11, Issue 3, Page 175-179, 2003., 2003 The development of an acute parvovirus B‐19 infection during pregnancy can cause pregnancy complications ranging from early pregnancy loss to nonimmune hydrops. There is no treatment, but preventive measures can be used to decrease perinatal mortality. The diagnosis is made on the basis of clinical suspicion and serology.
Anthony Al-Khan +2 more
wiley +1 more source
Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome [PDF]
, 2018 Adeno-associated virus (AAV) is a small human Dependovirus whose low immunogenicity and capacity for long-term persistence have led to its widespread use as vector for gene therapy.
Henckaerts, E +26 more
core +1 more source
Advances in AAV Vector Development for Gene Therapy in the Retina [PDF]
, 2014 Adeno-associated virus (AAV) is a small, non-pathogenic dependovirus that has shown great potential for safe and long-term expression of a genetic payload in the retina.
Flannery, John G +7 more
core +1 more source