Results 11 to 20 of about 6,673 (141)
Non‐A to E hepatitis in children: Detecting a novel viral epidemic during the COVID‐19 pandemic
During the COVID‐19 pandemic, two further novel viral epidemics were described in 2022, monkeypox virus infections in men having sex with men and non‐A to E hepatitis in children.
Harald Brüssow
doaj +2 more sources
Novel Parvoviruses from Wild and Domestic Animals in Brazil Provide New Insights into Parvovirus Distribution and Diversity [PDF]
Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified.
William Marciel de Souza +16 more
doaj +5 more sources
Liver virome of a Little Corella (Cacatua sanguinea) reveals coinfection with a novel parvovirus and two beak and feather disease viruses [PDF]
Emerging diseases are acknowledged as a growing threat to wildlife, with the continued identification of pathogenic and potentially pathogenic viruses in avian species resulting from ongoing advances in molecular diagnostic techniques. Parvoviruses under the genus Chaphamaparvovirus (subfamily Hamaparvovirinae) are highly divergent.
M Sutherland, S Sarker
wiley +3 more sources
Abstract Recombinant adeno‐associated virus (rAAV) is an extremely attractive vector in the in vivo delivery of gene therapy as it is safe and its genome is simple. However, challenges including low permissiveness to specific cells and restricted tissue specificity have hindered its clinical application.
Xiaoping Huang +7 more
wiley +1 more source
Abstract Despite the devastating clinical outcome of the neurodegenerative disease, amyotrophic lateral sclerosis (ALS), its etiology remains mysterious. Approximately 90% of ALS is characterized as sporadic, signifying that the patient has no family history of the disease.
Jessica Merjane +3 more
wiley +1 more source
The Analysis of Oral and Fecal Virome Detects Multiple Novel Emerging Viruses in Snakes
Wild animals are considered reservoirs for emerging and reemerging viruses, such as the novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Previous studies have reported that bats and ticks harbored variable important pathogenic viruses, some of which could cause potential diseases in humans and livestock, while viruses carried by ...
Aijing Liu +13 more
wiley +1 more source
Seroprevalence to adeno‐associated virus type 6 in people with hemophilia B from a UK adult cohort
Abstract Background Gene therapy shows promise as a potential “cure” for hemophilia A and B. Adeno‐associated virus (AAV) vectors are the leading platform to deliver modified genetic code of factor VIII or IX to the liver effecting endogenous production. Patient exposure to wild‐type AAV leads to the formation of neutralizing factors, which can prevent
Sara Boyce +9 more
wiley +1 more source
This review focus on the advancements of the molecular design of baculovirus vectors for high yield production of adeno‐associated virus (AAV) vectors for gene delivery describing the different generation of expression vectors with associated advantages and critical limitations.
Pranav R.H. Joshi +3 more
wiley +1 more source
Introducción. La mucopolisacaridosis IV A (Morquio A) es una enfermedad de depósito lisosómico causada por la deficiencia en la actividad de la enzima N-acetil-galactosamina- 6-sulfato-sulfatasa que produce la acumulación intralisosómica de queratán y ...
Luis Alejandro Barrera +6 more
doaj +1 more source
Parvovirus-derived endogenous viral elements in two South American rodent genomes [PDF]
We describe endogenous viral elements (EVEs) derived from parvoviruses (family <i>Parvoviridae</i>) in the long-tailed chinchilla (<i>Chinchilla lanigera</i>) and degu (<i>Octodon degus</i>) genomes.
Abascal +20 more
core +1 more source

