ABSTRACT Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin‐1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the serum level of FLOT1 in OC patients and found that the serum concentration of FLOT1 as well as CA125 was
Bin Guan+7 more
wiley +1 more source
Invasiveness Prediction of Pulmonary Adenocarcinomas Using Deep Feature Fusion Networks [PDF]
Early diagnosis of pathological invasiveness of pulmonary adenocarcinomas using computed tomography (CT) imaging would alter the course of treatment of adenocarcinomas and subsequently improve the prognosis. Most of the existing systems use either conventional radiomics features or deep-learning features alone to predict the invasiveness. In this study,
arxiv
Determining the date of diagnosis – is it a simple matter? The impact of different approaches to dating diagnosis on estimates of delayed care for ovarian cancer in UK primary care [PDF]
Background Studies of cancer incidence and early management will increasingly draw on routine electronic patient records. However, data may be incomplete or inaccurate.
A Majeed+27 more
core +3 more sources
Advancements in the Application of the Intersection of Medicine and Engineering in Cancer Research
ABSTRACT Cancer research predominantly centers on diagnosis, treatment, and elucidation of underlying mechanisms. Nevertheless, the intricate nature of tumor genesis and development has rendered early diagnostic and therapeutic outcomes less than optimal, making tumor conquest a formidable challenge.
Haitao Chen+16 more
wiley +1 more source
Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction [PDF]
Primary Signet-ring cell carcinoma (Linitus Plastica) of the colon and rectum is a rare form of adenocarcinoma of the large intestine and has been reported to have an extremely poor prognosis. We report a case of Primary Signet-ring cell carcinoma of the
Jagtap, SS+4 more
core
Investigating the benefits of molecular profiling of advanced non-small cell lung cancer tumors to guide treatments. [PDF]
In this study we utilized data on patient responses to guided treatments, and we evaluated their benefit for a non-small cell lung cancer cohort. The recommended therapies used were predicted using tumor molecular profiles that involved a range of ...
Alifrangis, C+11 more
core +2 more sources
ABSTRACT Lung adenocarcinoma is a common malignancy that can metastasize. The lung is also a common site for metastasis from other sites. Prompt and accurate diagnosis is critical for patient management. The diagnosis of lung adenocarcinoma can be occasionally challenging due to overlapping clinical and pathological features with adenocarcinomas from ...
Robert Pei+2 more
wiley +1 more source
Development of extrahepatic bile ducts and mechanisms of tumorigenesis: Lessons from mouse models
Abstract The biliary system is a highly branched tubular network consisting of intrahepatic bile ducts (IHBDs) and extrahepatic bile ducts (EHBDs). IHBDs are derived from hepatic progenitor cells, while EHBDs originate directly from the endoderm through a separate branching morphogenetic process.
Hiroyuki Tomita, Akira Hara
wiley +1 more source
Mucocele of the appendix: An unusual cause of lower abdominal pain in a patient with ulcerative colitis [PDF]
The authors report the case of a 60-year-old male patient. In November 2001 he developed intestinal symptoms of bloody diarrhea and abdominal pain. Colononoscopy and biopsy established the diagnosis of ulcerative colitis (proctosigmoiditis).
Fuszek, Péter+7 more
core
ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course.
Jamie C. Y. Lam+3 more
wiley +1 more source