Results 141 to 150 of about 48,384 (279)

Laryngopharyngeal Reflux: The Impact of Obesity

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This article provides an overview of gastro‐esophageal (GERD) and laryngopharynegal (LPRD) reflux diseases in the context of obesity as a confounding entity. A detailed review of the clinical presentation, pathogenesis, diagnosis, and treatment of laryngopharyngeal reflux disease may be found elsewhere.
Abdul Latif H. Hamdan, Mary J. Hawkshaw, Robert T. Sataloff   +2 more
wiley   +1 more source

Promoting Pancreatic Fistula Healing After Pancreaticoduodenectomy Through Internal Drainage of Pancreatic Juice Into the Jejunum

World Journal of Surgery, EarlyView.
Drain‐tract‐targeted management and fistulography are important in the treatment of Postoperative pancreatic fistula (POPF). Internal drainage into the jejunum significantly improved POPF healing after pancreaticoduodenectomy. ABSTRACT Background Postoperative pancreatic fistula (POPF) is a significant complication of pancreaticoduodenectomy (PD ...
Yoshihiro Miyazaki, Shinji Hashimoto, Osamu Shimomura, Hiromitsu Nakahashi, Manami Doi, Kazuhiro Takahashi, Jaejeong Kim, Shuntaro Tsukamoto, Kinji Furuya, Yohei Owada, Koichi Ogawa, Yoshimasa Akashi, Tsuyoshi Enomoto, Tatsuya Oda   +13 more
wiley   +1 more source

CGM2, a Member of the Carcinoembryonic Antigen Gene Family is Down- Regulated in Colorectal Carcinomas [PDF]

, 1994
We have determined the precise chromosomal location, the exon structure, and the expression pattern of CGM2, a member of the carcinoembryonic antigen (CEA) gene family.
Craig, Ian, Neumaier, Michael, Nollau, Peter, Schrewe, Heinrich, Thompson, John A., Weber-Arden, Julia, Willcocks, Teresa, Zimmermann, Wolfgang   +7 more
core  

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Ligand‐Based CAR‐T Cells Targeting EGFR Exhibit Favorable Antitumor Effects Against Gynecologic Malignancies

Cancer Science, EarlyView.
Wide variety of gynecologic malignancies express EGFR at high rates. Memory‐rich EGFR CAR‐T cells can be made by piggyBac‐mediated gene transfer with immature dendritic cells and EGFR protein. Ligand‐based EGFR CAR‐T cells have robust antitumor effects against gynecologic malignancies in vivo and in vitro.
Manaka Shinagawa, Koichi Hirabayashi, Marina Fujioka, Kyosuke Kamijo, Natsuki Uchiyama, Yusuke Yokokawa, Yasuhiro Tanaka, Motoki Ono, Thanyavi Chinsuwan, Ryoichi Asaka, Aiko Hasegawa, Miyuki Tanaka, Takashi Murakami, Shigeki Yagyu, Tsutomu Miyamoto, Tanri Shiozawa, Yozo Nakazawa   +16 more
wiley   +1 more source

Mucinous adenocarcinoma in kidneys with developmental anomalies - a report of two cases

BMC Urology
Background Primary mucinous adenocarcinomas of the kidney are rare and pose a challenge for preoperative diagnosis. The histogenesis of these tumours remains largely unknown, with three proposed theories: chronic irritation, differentiation of celomic ...
Kasi Viswanath Gali, Arun Chawla, K. R. Surag, Sunil Pillai Bhaskara, Padmaraj Hegde   +4 more
doaj   +1 more source

A 14‐Gene Panel for Predicting Colorectal Cancer Recurrence Using Circulating Tumor DNA in Different Testing Conditions

Cancer Science, EarlyView.
As circulating tumor DNA has emerged as a promising minimal residual disease biomarker, we evaluated circulating tumor DNA detection using a sensitive, targeted 14‐gene panel, the Sysmex Plasma‐Safe‐SeqS colorectal cancer assay, in resectable colorectal cancer cases.
Yuichi Hisamatsu, Koji Ando, Kensuke Kudo, Ryota Nakanishi, Tetsuro Kawazoe, Yoko Zaitsu, Tetsuya Kusumoto, Taishi Hata, Yoshinori Kagawa, Tomoharu Yoshizumi, Naoko Ashida, Hayato Niiro, Takashi Hirose, Eiji Oki   +13 more
wiley   +1 more source

Evaluation of the 2015 AGA guidelines on pancreatic cystic neoplasms in a large surgically confirmed multicenter cohort [PDF]

, 2017
Early, Dayna S, et al.,, Gaddam, Srinivas, Kushnir, Vladimir M, Mullady, Daniel   +4 more
core   +2 more sources

WHO Reporting System for Lung Cytopathology: Insights Into the Insufficient/Inadequate/Non‐Diagnostic, Atypical and Suspicious for Malignancy Categories and How to Use Them

Cytopathology, EarlyView.
The WHO System is an international effort to standardise category definitions, establish the key diagnostic cytopathological features of entities of the lung, propose the best use of ancillary tests in lung specimens, encourage the use of standardised pathology reports containing essential components in an integrated report and propose estimates of the
Zahra Maleki, Sule Canberk, Andrew Field
wiley   +1 more source

Stroma areactive invasion front areas (SARIFA) in 1,298 pT3/pT4 colorectal cancers: A strong prognostic parameter complementing established morphological criteria

Histopathology, EarlyView.
SARIFA is a novel, highly prognostic, stage‐independent morphological parameter in CRC. It complements established histopathological prognostic markers and provides crucial additional prognostic information across key clinicopathological and morphological subgroups. Partially created in https://BioRender.com.
Sebastian Foersch, Nuwar Harb, Anne‐Sophie Litmeyer, Wilfried Roth, Irina Breus, Johannes Schraml, Annika Weiß, Katja Steiger, Julia Teply‐Szymanski, Detlef K Bartsch, Carsten Denkert, Maxime Schmitt, Moritz Jesinghaus   +12 more
wiley   +1 more source