Results 141 to 150 of about 386,873 (322)

Metamorphoses in pancreatic cancer precursors: the role of simple mucinous cysts†

The Journal of Pathology, EarlyView.
Abstract Pancreatic cystic lesions present a unique opportunity to identify and potentially prevent pancreatic ductal adenocarcinoma (PDAC), one of the deadliest solid tumors. Until now, research has primarily focused on intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs), whose potential for malignant transformation ...
Paolo Riccardo Camisa, Daniele Campa, Irene Esposito, Stefano Crippa   +3 more
wiley   +1 more source

A Risk-Adjusted Model for Ovarian Cancer Care and Disparities in Access to High-Performing Hospitals. [PDF]

, 2020
ObjectiveTo validate the observed/expected ratio for adherence to ovarian cancer treatment guidelines as a risk-adjusted measure of hospital quality care, and to identify patient characteristics associated with disparities in access to high-performing ...
Bristow, Robert E, Chang, Jenny, Vieira, Veronica M, Villanueva, Carolina, Ziogas, Argyrios   +4 more
core  

A case of ROS1‐rearranged lung adenocarcinoma in a young man with multiple serosal effusions: Diagnostic pitfalls in pericardial fluid cytology

Precision Medical Sciences, EarlyView.
Abstract ROS1‐rearranged lung adenocarcinoma is a rare subset of non‐small‐cell lung cancer, typically occurring in young never‐smokers. Its occurrence in very young men with a fluid‐dominant presentation is unusual and may lead to diagnostic pitfalls.
Thanh Thao Nguyen, Marie Kawakami, Yoshiiku Okanemasa, Yumi Tsubata, Sohsuke Yamada   +4 more
wiley   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

Small, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch, Heike Danzer, Sirka Dormeyer, Shuhan Jiang, Fabian Herrmann, Matthias Weiler, Anna Kashkanova, Vahid Sandoghdar, Mario M. Zaiss, Gregor Fuhrmann   +13 more
wiley   +1 more source

Coexistence of Ovarian Mucinous Adeno Carcinoma and Benign Brenner Tumor: A Case Report

Gynecology Obstetrics & Reproductive Medicine, 2011
Mucinous ovarian tumors are known to coexist sometimes with Brenner tumors; however, in many of the cases in the literature, mucinous cystadenomas are seen to have been analyzed.
Özlem Seçilmiş Kerimoğlu, Pınar Karabağlı, Aybike Tazegül, Çetin Çelik   +3 more
doaj  

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

What the Eyelid Can Tell You: The Unexpected Initial Presentation of De Novo Stage IV Breast Carcinoma

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT A 66‐year‐old female presented with seven months of progressive right upper eyelid (RUL) drooping and thickening of her right lower eyelid (RLL). MRI revealed soft tissue enhancement of the RUL and RLL pre‐septal planes without posterior extension.
Grace L. Casado, Eileen Xu, Maedot A. Haymete, Nicholas A. Ramey, Douglas J. Grider   +4 more
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Interobserver variability of histopathological assessment in pT1 colorectal carcinoma

Histopathology, EarlyView.
Interobserver variability among 20 gastrointestinal pathologists was evaluated on 80 pT1 colorectal carcinoma cases. A pilot phase was followed by a consensus meeting, then a larger concordance study was performed. High interobserver agreement was achieved after consensus for histological grade, lymphovascular invasion, tumour budding, poorly ...
Karmele Saez de Gordoa, María Daca‐Alvarez, Maite Rodrigo‐Calvo, Ivan Archilla, Sandra Lopez‐Prades, Jose Javier Aguirre, Lorena Alarcón‐Molero, María Cámara Jurado, Adriana Canosa, Francisco Giner, Carmen González‐Lois, Mireya Jimeno, Ismael Jurado, Isidro Machado, Carolina Martínez‐Ciarpaglini, Eva Musulen, Dolores Naranjo, Natalia Papaleo, Cristina Peña, Òria Rosiñol, Rosario Sánchez‐Yuste, Greissy Tibisay Vázquez Benítez, María Pellisé, Miriam Cuatrecasas, on behalf of the EpiT1 Consortium   +24 more
wiley   +1 more source