Results 141 to 150 of about 387,731 (304)

Comparative study of imaging and pathology of primary mucinous adenocarcinoma with different imaging manifestations

open access: yesThe Clinical Respiratory Journal
Background Pulmonary mucinous adenocarcinoma is a special type of lung cancer. Its imaging manifestations are diverse, which brings challenges to clinical diagnosis. However, its formation mechanism is unclear. Objective The objective of this study is to
Jun Han   +9 more
doaj   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski   +7 more
wiley   +1 more source

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

open access: yesClinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron   +13 more
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Coexistence of Ovarian Mucinous Adeno Carcinoma and Benign Brenner Tumor: A Case Report

open access: yesGynecology Obstetrics & Reproductive Medicine, 2011
Mucinous ovarian tumors are known to coexist sometimes with Brenner tumors; however, in many of the cases in the literature, mucinous cystadenomas are seen to have been analyzed.
Özlem Seçilmiş Kerimoğlu   +3 more
doaj  

Claudin‐18 expression in gastric type adenocarcinoma and HPV‐associated adenocarcinoma of the uterine cervix

open access: yesHistopathology, EarlyView.
CLDN18 (43‐14A) is expressed in most gastric type adenocarcinomas and a much smaller proportion of HPV‐associated adenocarcinomas. Expression of CLDN18.2 mRNA but not CLDN18.1 mRNA is confirmed in both gastric type adenocarcinomas and HPV‐associated adenocarcinomas.
Nobuko Yasutake   +12 more
wiley   +1 more source

A Risk-Adjusted Model for Ovarian Cancer Care and Disparities in Access to High-Performing Hospitals. [PDF]

open access: yes, 2020
ObjectiveTo validate the observed/expected ratio for adherence to ovarian cancer treatment guidelines as a risk-adjusted measure of hospital quality care, and to identify patient characteristics associated with disparities in access to high-performing ...
Bristow, Robert E   +4 more
core  

Optimized workup of lymph nodes in regard to UICC classification of colorectal carcinoma

open access: yesHistopathology, EarlyView.
Treatment and outcome of colon cancer depend significantly on the histopathological examination of lymph nodes. Methodologically, stepwise sectioning and immunohistochemistry are the primary methods used. The extent of this examination is subject to debate but should be maintained at an adequate level in routine laboratory work.
Moritz Rust   +6 more
wiley   +1 more source

Making sense of TILs: recommendations for morphological assessment of tumour‐infiltrating lymphocytes in gastro‐oesophageal carcinoma

open access: yesHistopathology, EarlyView.
This review examines the role of tumour‐infiltrating lymphocytes (TILs) in gastro‐oesophageal carcinoma (GEC), focusing on their composition, clinical relevance and therapeutic utility. It proposes a framework for standardised evaluation and reporting of TILs, addressing GEC‐specific pathology challenges to support the widespread use and validation of ...
Ylva A Weeda   +38 more
wiley   +1 more source

Aquaporin‐1 differentiates intrahepatic cholangiocarcinoma from liver metastases of pancreatic ductal adenocarcinoma

open access: yesHistopathology, EarlyView.
Differentiating intrahepatic CCA from PDAC metastatic to the liver is critical for the clinical management of patients with pancreatobiliary cancers. AQP1 has demonstrated an excellent discriminatory performance in this clinical scenario. Aims Differentiating intrahepatic cholangiocarcinoma (iCCA) from metastatic ductal adenocarcinoma of the pancreas ...
Leoncini Giuseppe   +7 more
wiley   +1 more source

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