Results 161 to 170 of about 48,384 (279)

Mapping the Metastatic Landscape: A Population‐Based Cohort Study for Prognostic Insights Into Newly Diagnosed Stage IV Breast Cancer Cases

Cancer Innovation, Volume 4, Issue 5, October 2025.
This study represents comprehensive analysis of metastasis' anatomical distribution and prognosis in breast cancer, offering invaluable insights into metastatic tendencies and characteristics. ABSTRACT Background Breast cancer is the most common malignancy and a leading cause of cancer‐related deaths among women worldwide.
Xiangyi Kong, Qiang Liu, Zheng Qu, Xiangyu Wang, Wenxiang Zhang, Yulu Liu, Robert Coleman, Chunqing Lin, Jing Wang   +8 more
wiley   +1 more source

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

MedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi, Izuchukwu F. Okpalanwaka, Adenike Oyegbesan, Ebenezar Okoyeocha, Mariam Oladejo, Sikiru O. Imodoye   +5 more
wiley   +1 more source

Temporal trends in incidence and mortality of colorectal cancer in Denmark from 2007 to 2022

International Journal of Cancer, Volume 157, Issue 4, Page 634-643, 15 August 2025.
What's new? Colorectal cancer (CRC) is the third most common cancer in the Western world. Widespread use of screening programs has helped raise awareness of the disease and improve survival rates. To make sure screening, treatment, research, and education goals stay relevant, it is important to collect accurate population‐based estimates of CRC ...
Ida Ravnsbæk Johannsen, Anders Kindberg Boysen, Frank V. Mortensen, Jakob Kirkegård   +3 more
wiley   +1 more source

Urachal Villous Adenoma Coexistent With Urachal Carcinoma: A Case Report [PDF]

IJU Case Rep
ABSTRACT Introduction Urinary tract villous adenomas are uncommon, urachal villous adenomas being especially rare. While their malignant potential remains uncertain, villous adenomas may have malignant components. Here, we present a case of the coexistence of a urachal villous adenoma and urachal carcinoma. Case Presentation We report the case of an 86‐
Hatano S, Shimizu Y, Fujii H, Hayashi K, Maekawa K, Miyauchi Y, Sakurai T, Mitsumori K, Onishi H.   +8 more
europepmc   +2 more sources

Safety and Oncologic Outcomes of Endoscopic Endonasal Transcribriform Approach for Locally Advanced Sinonasal Malignancies

Head &Neck, Volume 47, Issue 8, Page 2348-2357, August 2025.
ABSTRACT Introduction The past two decades have seen a paradigm shift in the surgical treatment of sinonasal malignancies, moving from traditional open approaches to minimally invasive endoscopic techniques. Technological advancements have enabled the use of the endoscopic endonasal transcribriform approach (EETA) for tumors involving the anterior ...
Michel Khalaf, Héloïse De Kermadec, Juliette Hershkovitch, Odile Casiraghi, Gabriel Garcia, François Bidault, François‐Régis Ferrand, France Nguyen, Stéphane Temam, Pierre Blanchard, Damien Bresson, Antoine Moya Plana   +11 more
wiley   +1 more source

The Characteristics of Prostate Mucinous Adenocarcinoma Visualized by 68 Ga-PSMA, 68 Ga-FAPI, and 18 F-FDG PET/CT. [PDF]

Clin Nucl Med
Sun Z, Jiang X, Fu G, Sun S, Tao W.
europepmc   +1 more source

Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization

The Journal of Pathology, Volume 266, Issue 4-5, Page 421-434, August 2025.
Abstract Mucinous cystic neoplasms (MCNs) of the pancreas are macroscopic precursors of pancreatic cancer. A similar cystic lesion but lacking the ovarian‐type subepithelial stroma has been recently defined as a simple mucinous cyst (SMC); however, its nature remains unclear. This study aims to define the clinicopathological and molecular profiles of a
Antonio Pea, Michele Bevere, Anastasios Gkountakos, Davide Pasini, Denise Fiorini, Andrea Mafficini, Stela Golovco, Michele Simbolo, Serena Pedron, Concetta Sciammarella, Paola Mattiolo, Aldo Mombello, Manuela Villanova, Carlotta Franzina, Francesca Masetto, Calogero Ciulla, Nicola Sperandio, Kohei Fujikura, Masha S. Ahadi, Jaswinder S. Samra, Amber L. Johns, Joanne Verheij, Martijn W.J. Stommel, Hjalmar van Santvoort, Leonor Schubert Santana, Giuseppe Malleo, Michele Milella, Lodewijk A. A. Brosens, Laura D. Wood, David K. Chang, Riccardo De Robertis, Mirko D'Onofrio, Anthony J. Gill, Roberto Salvia, Vincenzo Corbo, Rita T. Lawlor, Aldo Scarpa, Claudio Luchini   +37 more
wiley   +1 more source

Gene expression in tumor and adjacent normal tissues in lung adenocarcinoma subtypes. [PDF]

BMC Cancer
Gorlova OY, Gorlov IP, Ripley RT, Cheng C, Li Y, Peng B, Liu Y, Jang HJ, Kang SW, Lee C, Ranchod P, Burt BM, Lee HS, Amos CI.   +13 more
europepmc   +1 more source

Clinicopathological and molecular characterization of KRAS wild-type pancreatic ductal adenocarcinomas reveals precursor lesions with oncogenic mutations and fusions in RAS pathway genes. [PDF]

J Pathol
Abstract Pancreatic ductal adenocarcinomas (PDACs) with wild‐type KRAS constitute a small fraction of PDACs, and these tumors were recently shown to harbor frequent actionable oncogenic mutations and fusions. However, the clinicopathological features of KRAS wild‐type PDAC have not been well studied.
Toriyama K, Masago K, Shibata N, Haneda M, Kuwahara T, Natsume S, Kobayashi S, Fujita Y, Sasaki E, Yamao K, Kawashima H, Shimizu Y, Hara K, Yatabe Y, Hosoda W.   +14 more
europepmc   +2 more sources

Colorectal Carcinoma in Childhood and Adolescence: Microsatellite Instability Correlates With a Favorable Prognosis

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Colorectal cancer (CRC) accounts for 10% of cancer cases worldwide; however, pediatric CRC is extremely rare, with an annual incidence of one to two cases per million. Microsatellite instability (MSI) has been shown to play a relevant prognostic role in adult CRC. Corresponding data for pediatric CRC are lacking. This study examines
Hannah Wild, Alexandra Liebmann, Lucas Maennel, Linda Maschke, Andreas Block, Leo Kager, Udo Kontny, Abbas Agaimy, Michaela Kuhlen, Antje Redlich, Andreas Schmidt, Jörg Fuchs, Dominik T. Schneider, Ines B. Brecht, Michael Abele   +14 more
wiley   +1 more source