Results 211 to 220 of about 358,784 (300)

The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma

open access: yesNature Cell Biology, 2014
G. Figura   +14 more
semanticscholar   +1 more source

Pancreatic Cancer: Pathogenesis and Clinical Studies

open access: yesMedComm, Volume 6, Issue 4, April 2025.
Although the treatment landscape for cancer has evolved rapidly in recent years, progress has stagnated for pancreatic cancer (PC). PC includes multiple types, but pancreatic ductal adenocarcinoma (PDAC) accounts for >90% of cases. This review focuses on the molecular pathogenesis and different treatments for PDAC, hoping to propose future directions ...
Kexun Zhou   +3 more
wiley   +1 more source

Comprehensive characterization of micropapillary colorectal adenocarcinoma

open access: yesThe Journal of Pathology, Volume 265, Issue 4, Page 408-421, April 2025.
Abstract Micropapillary colorectal adenocarcinoma is a morphologic subtype of colorectal cancer (CRC) with insufficiently characterized prognostic significance and biological features. We analyzed the histopathological, immunological, and prognostic features of micropapillary adenocarcinoma in two independent CRC cohorts (N = 1,876).
Ville K Äijälä   +25 more
wiley   +1 more source

Unveiling the intriguing relationship: oncogenic KRAS, morphological shifts, and mutational complexity in pancreatic mucinous cystic neoplasms

open access: yesThe Journal of Pathology, Volume 265, Issue 4, Page 401-407, April 2025.
Abstract Pancreatic ductal adenocarcinoma (PDAC) often arises from preexisting cystic lesions such as intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms (MCN). This study investigated the molecular heterogeneity and mutational landscape of MCN in relation to PDAC, highlighting the significance of KRAS mutations in tumor ...
Lucas‐Alexander Schulte   +22 more
wiley   +1 more source

Micropillars in Cell Mechanobiology: Design, Fabrication, Characterization, and Biosensing Applications

open access: yesSmall Science, Volume 5, Issue 4, April 2025.
In this article, the pivotal role of micropillars in cell mechanobiology is explored, detailing their design, fabrication, and characterization. Novel applications in biosensing are highlighted, emphasizing their ability to modulate cellular environments and facilitate mechano‐stimulation.
Prabuddha De Saram   +3 more
wiley   +1 more source

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