Results 71 to 80 of about 386,873 (322)

Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge. [PDF]

, 2016
Primary appendiceal mucinous lesions are uncommon and represent a spectrum from nonneoplastic mucous retention cysts to invasive adenocarcinoma. Low-grade appendiceal mucinous neoplasms (LAMNs) represent an intermediate category on this spectrum and can ...
Baumgartner, Joel M, Ko, Albert, Saenz, Cheryl C, Valasek, Mark A, Vavinskaya, Vera   +4 more
core   +4 more sources

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

A prognostic model of patients with ovarian mucinous adenocarcinoma: a population-based analysis

Journal of Ovarian Research, 2022
Background Ovarian mucinous carcinoma is a disease that requires unique treatment. But for a long time, guidelines for ovarian serous carcinoma have been used for the treatment of ovarian mucinous carcinoma.
Li Yang, Jinfen Yu, Shuang Zhang, Yisi Shan, Yajun Li, Liugang Xu, Jinhu Zhang, Jianya Zhang   +7 more
doaj   +1 more source

Incidence of lymph node metastases in clinical early-stage mucinous and seromucinous ovarian carcinoma: a retrospective cohort study [PDF]

, 2017
Objective: The use of lymph node sampling during staging procedures in clinical early-stage mucinous ovarian carcinoma (MOC) is an ongoing matter of debate. Furthermore, the incidence of lymph node metastases (LNM) in MOC in relation to tumour grade (G)
Buist, M.R., Coffelt, S.B., Kenter, G.G., Lok, C.A.R., van Baal, J.O.A.M., Van de Vijver, K.K., van der Noort, V., van Driel, W.J.   +7 more
core   +2 more sources

Gene signature driving invasive mucinous adenocarcinoma of the lung

EMBO Molecular Medicine, 2017
Though invasive mucinous adenocarcinoma of the lung (IMA) is pathologically distinctive, the molecular mechanism driving IMA is not well understood, which hampers efforts to identify therapeutic targets.
M. Guo, K. Tomoshige, M. Meister, T. Muley, T. Fukazawa, T. Tsuchiya, Rebekah A. Karns, A. Warth, I. Fink-Baldauf, T. Nagayasu, Y. Naomoto, Yan Xu, M. Mall, Yutaka Maeda   +13 more
semanticscholar   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Giant mucinous adenocarcinoma of the appendix: a case report

Journal of Medical Case Reports, 2017
Background Appendiceal mucinous adenocarcinoma is an extremely rare disease in clinical practice. Here, we report a case of unprecedented size that occupied the entire abdomen of a man.
Sheng-Chun Dang, Ming-Ming Sun, Lu-Lu Liu, Abdul Malik, Jian-Xin Zhang, Yi-Yi Fan, Song Zou, Lei Cui, Jian-Guo Qu, Ji-Xiang Chen   +9 more
doaj   +1 more source

MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors [PDF]

, 2012
BACKGROUND MicroRNA (miRNA) expression profiles have been described in pancreatic ductal adenocarcinoma (PDAC), but these have not been compared with pre-malignant pancreatic tumors.
A Cimmino, A Grimson, A Keller, A Lal, A Singh, Adam E. Frampton, AE Szafranska, AE Szafranska, AL Warshaw, AM Bellizzi, AM Krichevsky, AN Bartley, Andreas Keller, BM Bolstad, C Almoguera, C Galanis, C Mayr, C Stefano, D Bartsch, D Bonci, DS Klimstra, DV Sahani, F Takeshita, FA Sinicrope, G Garcea, GA Calin, Georgios Giamas, GK Smyth, GK Smyth, H Matthaei, H Wang, J Lu, J Meister, J Torrisani, J Yu, Jimmy Jacob, Jonathan Krell, JS Desgrosellier, JS Oh, Justin Stebbing, K Izeradjene, K Ohuchida, K Satoh, K Yoshizawa, KC Miranda, L Castellano, L Xia, Leandro Castellano, Long R. Jiao, Loredana Pellegrino, M Bloomston, M Crawford, M Dillhoff, M Fabbri, M Goggins, M Seux, M Tanaka, Marc Tjwa, MC du Rieu, N Abe, N Habbe, Nagy A. Habib, Nicole Tsim, O Basturk, OA Kent, Panagiotis Vlavianos, Patrizia Cohen, R Bhattacharya, R Feng, Raida Ahmad, RI Aqeilan, S Griffiths-Jones, S Griffiths-Jones, S Hamada, S Mukherjee, S Reddy, S Vorwerk, S Watanabe, S Yu, SD Selcuklu, SF Tavazoie, SM Johnson, SYG Friedlander, T Ishikawa, T Paranjape, WA Mardin, WG Zhao, WR Brugge, X Chen, X Li, Y Akao, Y Benjamini, Y Hochberg, YJ Chua   +93 more
core   +4 more sources

Prognostic Impact of Immunoscore in Pathological Stage III Differentiated Gastric Cancer: A Multicenter Cohort Study Including PD‐L1/PD‐L2 Expression Analysis

Annals of Gastroenterological Surgery, EarlyView.
We assessed the prognostic ability of the Immunoscore and PD‐L1 or PD‐L2 expression in pStage III GC patients by immunohistochemistry. The results showed that Immunoscore was an independent prognostic factor in differentiated GC, but not in undifferentiated GC.
Yoshiro Yukawa, Takuro Saito, Yukinori Kurokawa, Yusuke Akamaru, Shinya Kidogami, Hiroshi Imamura, Kazumasa Fujitani, Jin Matsuyama, Kazuyoshi Yamamoto, Tsuyoshi Takahashi, Takahiro Matsui, Eiichi Morii, Hidetoshi Eguchi, Yuichiro Doki   +13 more
wiley   +1 more source

Phenotypic and Genotypic Appraisal of Pulmonary Mucinous Adenocarcinoma: A Retrospective Study

National Journal of Laboratory Medicine, 2023
Introduction: Lung cancer is the second most common cancer diagnosed in the world. According to GLOBOCAN 2020, it is approximately 11.4% of all malignancies and accounts for one in five cancer deaths worldwide.
VG Deepak Roshan, Ashwini Ramji, M Saravanan, Vipin Gopinath, Sangeetha K Nayanar   +4 more
doaj   +1 more source