Results 111 to 120 of about 161,386 (190)

Sebaceous adenoma of the cheek

, 2002
Sebaceous adenoma is a tumour only rarely located in the oral cavity. Less than 10 cases have been reported, Sebaceous adenoma represents 0.5-0.7% of all monomorphic adenomas.
Fioroni, M, Rubini, C, PIATTELLI, Adriano, IEZZI, GIOVANNA   +3 more
core   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

Phytotherapy Research, Volume 40, Issue 10, Page 5973-5987, October 2026.
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Md. Rezaul Islam, Abdur Rauf, F. M. Shourav, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Kamala Badalova, Marcello Iriti   +7 more
wiley   +1 more source

Metronidazole and Eugenol Hybrids as an Alternative Against Multidrug‐Resistant Bacteria

ChemistrySelect, Volume 11, Issue 39, 20 October 2026.
Structures of the synthesized hybrid compounds AC1–AC8. Figure adapted from Pelozo et al. ABSTRACT Antibiotic resistance is a global threat to human and animal health, since several bacterial species have developed different forms of resistance. Therefore, it is essential to seek effective methods to combat bacterial resistance. Research indicates that
João Arthur de Oliveira Borges, Lucas dos Santos Sa, Francisco Ruan Moreira da Silva Santos, Cicera Laura Roque Paulo, Raimundo Luiz Silva Pereira, Daniel Sampaio Alves, Ana Carolina Justino de Araújo, Francisco Nascimento Pereira Junior, Ana Laura Marques Trinca, Douglas Henriques Novais Junior, Lucas Lopardi Franco, Janaína Esmeraldo Rocha, Henrique Douglas Melo Coutinho, Maria Karollyna do Nascimento Silva Leandro   +13 more
wiley   +1 more source

α‐Synuclein Promotes Atherosclerosis by Impairing Macrophage Autophagic Flux

Aging Cell, Volume 25, Issue 10, October 2026.
Extracellular α‐synuclein activates the FLOT1‐PI3K‐mTOR axis to block autophagosome‐lysosomal fusion and lipophagy, thereby promoting macrophage foaming and atherosclerosis. Knockdown of FLOT1 or inhibition of PI3K‐mTOR rescues these effects. The graphical abstract image was created with Figdraw.
Mengting Qin, Xuying Xiang, Xiaoqing Guo, Shengnan Wang, Jiaojiao Chen, Dailiang Jiang, Yuhang Feng, Jiangnan Yu, Ling Mao   +8 more
wiley   +1 more source

Triazole‐Linked Pyrimidine Nucleoside Dimers: Design, Synthesis, and Applications in Medicinal and Nucleic Acid Chemistry. Part IV

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
A series of 18 pyrimidine nucleoside dimers analogues with a short 1,4‐disubstituted 1,2,3‐triazole linkage were synthesized using a click chemistry approach (CuAAC). Analysis of the obtained products was conducted utilizing 1D/2D NMR spectroscopy (1H, 13C, 19F, 15N, and 29Si), mass spectrometry (ESI‐MS), and high‐performance liquid chromatography ...
Dagmara Baraniak, Dariusz Wawrzyniak, Daniel Baranowski   +2 more
wiley   +1 more source

Lipid Accumulation Promotes Tumorigenic Behaviour of Colorectal Cancer Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Obesity and hyperlipidemia are risk factors for the development and progression of different types of cancer including colorectal cancer (CRC). The underlying mechanisms are only incompletely understood. The aim of this study was to assess the impact of hyperlipidemic conditions on tumorigenic behaviour of CRC cells and the effect of obesity ...
Tatjana Itzenhäuser, Fulya Suzan Schildt, Seraphine Jochem, Judith Sommer, Michael Stürzl, Elisabeth Naschberger, Anja Katrin Boßerhoff, Claus Hellerbrand   +7 more
wiley   +1 more source

Sebaceous gland epithelioma with potential malignancy in a dog

Sebaceous gland tumors consist of neoplastic proliferations of sebaceous gland cells located around hair follicles in the dermis. These tumors are subclassified as sebaceous epithelioma, sebaceous adenoma, sebaceous adenocarcinoma and nodular hyperplasia.
Kayıkcı, Caner, Çiçek, Hacı Ahmet, Kuşçu, Yağmur, Keleş, Ömer Faruk   +3 more
core   +1 more source

Sebaceous Gland Hyperplasia

, 2016
Sebaceous gland hyperplasia refers to hypertrophic enlargement of the sebaceous glands. Though benign, its predilection for cosmetically sensitive areas such as the face make efficacious treatment options desirable.
Robert A. Schwartz, Stone, Rivka C, Rivka C. Stone, Schwartz, Robert A   +3 more
core   +1 more source

Design, Synthesis, and Biological Evaluation of Pyrazolyl Thioureas (PTUs) as SIRT1 and SIRT2 Inhibitors

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Pyrazolyl thioureas were designed and synthesized as sirtuin 1 (SIRT1) and sirtuin 2 (SIRT2) inhibitors. 6a (IC50 (SIRT1) = 5.3 µM; IC50 (SIRT2) = 2.2 µM) and 7f (IC50 (SIRT1) = 12.4 µM; IC50 (SIRT2) = 13.6 µM) showed micromolar inhibition on target enzymes and HepG2‐based assays confirmed a SIRT2‐mediated effect on tubulin acetylation. Docking studies
Matteo Lusardi, Cecilia Astigiano, Deianira Bellitto, Matteo Raineri, Giorgia Guccione, Annalisa Salis, Elena Cichero, Chiara Brullo, Marco Ponassi, Santina Bruzzone, Andrea Spallarossa   +10 more
wiley   +1 more source

Caracterización clinicopatológica de los tumores malignos palpebrales

Revista Cubana de Oftalmología
Objetivos: describir las características clinicopatológicas de los tumores malignos palpebrales. Métodos: estudio descriptivo y retrospectivo de pacientes con diagnóstico histopatológico de carcinoma basocelular, epidermoide y adenocarcinoma de glándulas
Lázara Kenia Ramírez García, Datia Liset Ortiz Ramos, Clara Gisela Gómez Cabrera, Lázaro Vigoa Aranguren, Irene Rojas Rondón, Franklyn Alain Abreu Perdomo   +5 more
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