Results 71 to 80 of about 6,097 (212)

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

The FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira, Solon Andrades da Rosa, Luiza Cherobini Pereira, Laura Boose de Mendonça, Juliete Scholl, Fabrício Figueiró, Thais Cardoso Bitencourt, Davi Piovesan Echevarria, João Luiz Aldinucci Buzzo, Jessica Boschini D'Agostin, Danieli Rosane Dallemole, Carolina Oliveira, Fernanda Simas, Fernanda Saez‐Calazans, Débora Santos‐Sousa, Guido Lenz, Eduardo C. Filippi‐Chiela   +16 more
wiley   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

The FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs, Enikő Lakatos, Dalma Feil‐Börcsök, Gábor Juhász, Regina Mező, Asha Kiran Maddali, András Blastyák, Aladár Pettkó‐Szandtner, Hajnalka Laczkó‐Dobos, Gábor Juhász   +9 more
wiley   +1 more source

Clinicopathological and Prognostic Features of Pleomorphic Adenoma, Recurrent Pleomorphic Adenoma, and Carcinoma ex Pleomorphic Adenoma: A 20‐Year Retrospective Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Pleomorphic adenoma (PA) is the most common salivary gland tumor, and a subset may recur as recurrent PA (RPA) or progress to carcinoma ex pleomorphic adenoma (CXPA). However, comparative evaluations of their biological behavior and prognostic factors remain limited.
Talita de Carvalho Kimura, Luccas Lavareze, Reydson Alcides de Lima‐Souza, Nívia Castro Binda, Carlos Takahiro Chone, Alfio José Tincani, Albina Altemani, Fernanda Viviane Mariano   +7 more
wiley   +1 more source

Valorization of fruit pits from Prunus laurocerasus and Prunus cerasifera as agro‐food byproducts: Bioactive properties and safety assessment for potential food additive applications

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 6002-6014, 15 August 2026.
Abstract BACKGROUND Food additives are widely used to extend the shelf life of foods and maintain their quality. In this study, the potential of Prunus laurocerasus and Prunus cerasifera fruit pits (endocarp and seed) as food additives was investigated in terms of cytotoxicity, antigenotoxicity, antioxidant activity, enzymatic anti‐browning, and urease
Zühal Bayrakçeken Güven, Mehmet Karadayı, Mustafa Abdullah Yilmaz, Osman Tugay, Oguz Cakir   +4 more
wiley   +1 more source

Investigating orbital foreign device-associated malignancies: a scoping review

BMC Cancer
Background While prosthesis-associated malignancies have been acknowledged, awareness among surgeons and patients in the ophthalmologic field remains limited, despite the frequent occurrence of prosthesis-related surgeries.
Jeong Hyun Ha, Jagmeet S. Arora, Jamasb J. Sayadi, Nada R. Khattab, Shannon D. Francis, Thomas M. Johnstone, Yeonji Jang, Gordon K. Lee   +7 more
doaj   +1 more source

Effects of Lactobacillus‐Mediated Functionalization of Dendrobium officinale Polysaccharides: A Study From Physicochemical Properties and Structural Changes to Anti‐Inflammatory Activity

eFood, Volume 7, Issue 4, August 2026.
Lactic acid bacteria (LAB) fermentation cleaves specific glycosidic bonds in Dendrobium officinale polysaccharides (DOPs), reducing molecular weight and enhancing anti‐inflammatory activity through regulation of inflammatory cytokines, oxidative stress, and intestinal barrier function.
Dingding Hong, Hui Ye, Xiaojun Huang
wiley   +1 more source

Comparative Evaluation of the Cytotoxic Effect of Dysphania ambrosioides Extracts Against Human Breast and Cervical Cancer Cells

Chemistry &Biodiversity, Volume 23, Issue 7, July 2026.
This study evaluates the geographic influence on the chemical and biological profiles of Dysphania ambrosioides collected from Brazilian and Colombian sources. Following extraction, metabolic fingerprinting via HPLC‐MS reveals distinct phytochemical variations between the geographical origins.
Andres Camilo Moreno Abadia, Lina Marcela Trujillo Chacón, Júlia Biz Willig, Edison Osorio, Diogo André Pilger, Miriam Anders Apel, Simone Cristina Baggio Gnoatto   +6 more
wiley   +1 more source

Metastatic Unfunctional Pancreatic Neuroendocrine Tumor in Lynch Syndrome

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Lynch syndrome (LS), a well‐known cancer risk syndrome, is caused by deleterious germline mutations in the mismatch repair genes. LS predispose patients to various types of cancers including colon adenocarcinoma. We discuss the case of a woman with LS who also developed a non‐functioning pancreatic neuroendocrine tumor (P‐NET) following ...
Fateme Salemi, Zahra Sadin, Atefe Barzegari, Seyed Mohammad Reza Mortazavizadeh, Massih Bahar, Motahare Amiri   +5 more
wiley   +1 more source

Case Report: Successful treatment of a case of Lynch syndrome with double primary ovarian and rectal cancer

Frontiers in Oncology
BackgroundLynch syndrome (LS), previously known as hereditary nonpolyposis colorectal cancer (CRC), is an autosomal dominant disorder characterized by germline variants in the mismatch repair (MMR) gene (e.g., MLH1 and MSH2) with microsatellite ...
Zhengliang Yu, Gang Yang, Jing Yue, Haiyan Liang, Man Yi, Yong Luo, Haixiao Fu, Zhenran Wang, Zhiyuan Jian, Yi Gao   +9 more
doaj   +1 more source

Quantitative Analysis of Cytologic Features: Application to Mucoepidermoid Carcinoma

Diagnostic Cytopathology, Volume 54, Issue 7, Page 519-527, July 2026.
ABSTRACT Introduction Cytologic diagnosis relies on recognition of morphologic features, yet the diagnostic value of individual cytologic features or their combinations is rarely quantified. In this study, we apply a quantitative cytologic feature analysis (QCFA) approach that treats each cytologic feature as a diagnostic test with measurable ...
John Effat Bacilious Diks, Saleh Najjar, Saroja D. Geetha, S. Mohsen Hosseini   +3 more
wiley   +1 more source