Results 131 to 140 of about 1,279,856 (386)

EGFR Mutation and Brain Metastasis in Pulmonary Adenocarcinomas [PDF]

, 2014
Dong‐Yeop Shin, Im Il Na, Cheol Hyeon Kim, Sunhoo Park, HeeJong Baek, Sung Hyun Yang   +5 more
openalex   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

Evaluating First-line Chemotherapy Regimens and Platinum Choices in HER2-Negative Metastatic Gastric Cancer: A Retrospective Analysis

Journal of Oncological Sciences
Objective: The survival advantage of triplet versus doublet chemotherapy regimens and cisplatin versus oxaliplatin-based therapies for first-line treatment in human epidermal growth factor receptor 2 (HER2)-negative metastatic gastric cancer remains ...
Caner ACAR, Haydar Çağatay YÜKSEL, Salih TÜNBEKİCİ, Gökhan ŞAHİN, Fatma Pınar AÇAR, Burçak KARACA   +5 more
doaj   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

First Line Androgen Deprivation Therapy vs. Chemotherapy for Patients With Androgen Receptor Positive Recurrent or Metastatic Salivary Gland Carcinoma—A Retrospective Study

Frontiers in Oncology, 2019
Objectives: There is a lack of effective therapy for recurrent or metastatic salivary gland carcinoma. Androgen deprivation therapy has demonstrated efficacy in cases of salivary duct carcinoma (SDC) and high-grade adenocarcinoma not otherwise specified (
Paul V. Viscuse, Katharine A. Price, Joaquin J. Garcia, David J. Schembri-Wismayer, Ashish V. Chintakuntlawar   +4 more
doaj   +1 more source

Procedure-Specific Risk Prediction for Recurrence in Patients Undergoing Lobectomy or Sublobar Resection for Small (≤2 cm) Lung Adenocarcinoma: An International Cohort Analysis [PDF]

, 2018
Sarina Bains, Takashi Eguchi, Arne Warth, Yi‐Chen Yeh, Jun‐ichi Nitadori, Kaitlin M. Woo, Teh‐Ying Chou, Hendrik Dienemann, Thomas Muley, Jun Nakajima, Aya Shinozaki‐Ushiku, Yu‐Chung Wu, Shaohua Lu, Kyuichi Kadota, David R. Jones, William D. Travis, Kay See Tan, Prasad S. Adusumilli   +17 more
openalex   +1 more source

Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro

Advanced Biology, EarlyView.
Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Alice Grossi, Paola Fulghieri, Abdurakhmon Aduvaliev, Karen Soffiantini, Irene Oldrati, Margherita Cavallo, Marco Biggiogera, Giorgia Pellavio, Umberto Laforenza, Monica Savio, Virginie Sottile   +10 more
wiley   +1 more source

Correlation of prostate-specific antigen levels with Gleason score and tumor percentage on prostate needle biopsy in prostate cancer

Journal of Dr. NTR University of Health Sciences
Introduction: Prostate-specific antigen (PSA) plays an important role in the detection of prostate cancer. Although it has high sensitivity and low specificity, it is still used clinically. A biopsy is recommended if any abnormality is detected in PSA or
Priyanka Singh, Rajpal Singh Punia, Harshi Dhingra, Vidur Bhalla   +3 more
doaj   +1 more source

ATM Dysfunction in Pancreatic Adenocarcinoma and Associated Therapeutic Implications [PDF]

, 2019
Samantha Armstrong, Christopher W. Schultz, Ariana Azimi-Sadjadi, Jonathan R. Brody, Michael J. Pishvaian   +4 more
openalex   +1 more source

AIM2 upregulation promotes metastatic progression and PD‐L1 expression in lung adenocarcinoma

, 2022
Jing‐Quan Zheng, Che‐Hsuan Lin, H Lee, Wei‐Min Chang, Lijie Li, Chia‐Yi Su, Kang‐Yun Lee, Hui‐Wen Chiu, Yuan‐Feng Lin   +8 more
openalex   +1 more source