Results 151 to 160 of about 823,307 (385)

Functionalized Cerium Oxide Nanoparticles Enhance Penetration into Melanoma Spheroids In Vivo through Angiogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu   +5 more
wiley   +1 more source

Exploring Gene Regulatory Interaction Networks and predicting therapeutic molecules for Hypopharyngeal Cancer and EGFR-mutated lung adenocarcinoma [PDF]

open access: yesarXiv
With the advent of Information technology, the Bioinformatics research field is becoming increasingly attractive to researchers and academicians. The recent development of various Bioinformatics toolkits has facilitated the rapid processing and analysis of vast quantities of biological data for human perception.
arxiv  

Primary adenocarcinoma of the esophagus [PDF]

open access: bronze, 1968
Alan D. Turnbull, John T. Goodner
openalex   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

open access: yesAdvanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen   +7 more
wiley   +1 more source

Acute Pancreatitis: A Rare Case of Primary Peripheral T-Cell Lymphoma-Not Otherwise Specified [PDF]

open access: yesMiddle East Journal of Cancer
Primary pancreatic lymphoma (PPL) represents a rare extranodal lymphoid malignancy, accounting for less than 2% of all lymphomas, 0.1% of malignant lymphomas, and 0.5% of pancreatic tumors.
Fatemeh Zarimeidani   +3 more
doaj  

Survival Prediction Across Diverse Cancer Types Using Neural Networks [PDF]

open access: yesarXiv
Gastric cancer and Colon adenocarcinoma represent widespread and challenging malignancies with high mortality rates and complex treatment landscapes. In response to the critical need for accurate prognosis in cancer patients, the medical community has embraced the 5-year survival rate as a vital metric for estimating patient outcomes.
arxiv  

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

open access: yesAdvanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle   +9 more
wiley   +1 more source

Preoperative Diagnostic Dilemma in Rapidly Progressive Mixed Neuroendocrine-Nonendocrine Neoplasm of the Ascending Colon: A Case Report

open access: yesCase Reports in Gastroenterology
Introduction: Mixed neuroendocrine-nonendocrine neoplasms (MiNENs) of the digestive tract are rare. They contain both neuroendocrine and nonendocrine components. We here report a rare case of a metastatic MiNEN originating in the ascending colon.
Masayo Kawakami   +8 more
doaj   +1 more source

Understanding Stain Separation Improves Cross-Scanner Adenocarcinoma Segmentation with Joint Multi-Task Learning [PDF]

open access: yesarXiv
Digital pathology has made significant advances in tumor diagnosis and segmentation, but image variability due to differences in organs, tissue preparation, and acquisition - known as domain shift - limits the effectiveness of current algorithms. The COSAS (Cross-Organ and Cross-Scanner Adenocarcinoma Segmentation) challenge addresses this issue by ...
arxiv  

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