Results 191 to 200 of about 1,279,856 (386)
Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy
Advanced Materials, EarlyView.This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez +9 morewiley +1 more sourceDoes pre‐operative chemoradiation for initially unresectable or borderline resectable pancreatic adenocarcinoma increase post‐operative morbidity? A case‐matched analysis [PDF]
, 2013 Raphael L. C. Araújo, Sébastien Gaujoux, F. Huguet, Mithat Gönen, Michael I. D’Angelica, Ronald P. DeMatteo, Yuman Fong, T. Peter Kingham, William R. Jarnagin, Karyn A. Goodman, Peter J. Allen +10 moreopenalex +1 more sourceIntegrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma.
Cancer Cell, 2017 Benjamin J. Raphael, R. Hruban, A. Aguirre, R. Moffitt, J. Yeh, C. Stewart, A. G. Robertson, A. Cherniack, M. Gupta, G. Getz, S. Gabriel, M. Meyerson, C. Cibulskis, S. Fei, T. Hinoue, Hui Shen, P. Laird, Shiyun Ling, Yiling Lu, G. Mills, Rehan Akbani, Phillipe Loher, Eric Londin, I. Rigoutsos, Aristeidis G. Telonis, E. Gibb, A. Goldenberg, A. Mezlini, K. Hoadley, E. Collisson, E. Lander, Bradley A. Murray, J. Hess, Mara W Rosenberg, Louis Bergelson, Hailei Zhang, Juok Cho, G. Tiao, Jaegil Kim, D. Livitz, I. Leshchiner, B. Reardon, E. Allen, A. Kamburov, R. Beroukhim, G. Saksena, S. Schumacher, M. Noble, David I Heiman, Nils Gehlenborg, M. Lawrence, V. Adsay, G. Petersen, D. Klimstra, N. Bardeesy, Mark D. M. Leiserson, R. Bowlby, K. Kasaian, I. Birol, K. Mungall, S. Sadeghi, J. Weinstein, P. Spellman, Yuexin Liu, L. Amundadottir, J. Tepper, A. Singhi, R. Dhir, Drwiega Paul, T. Smyrk, Lizhi Zhang, Paula Kim, Jay Bowen, J. Frick, J. Gastier-Foster, M. Gerken, Kevin R Lau, K. Leraas, T. Lichtenberg, N. Ramirez, Jeremy Renkel, M. Sherman, L. Wise, P. Yena, E. Zmuda, J. Shih, Adrian Ally, M. Balasundaram, R. Carlsen, Andy Chu, E. Chuah, A. Clarke, Noreen Dhalla, R. Holt, Steven J. M. Jones, Darlene Lee, Yussanne Ma, M. Marra, Michael Mayo, Richard A. Moore, A. Mungall, J. Schein, Payal Sipahimalani, Angela Tam, N. Thiessen, Kane Tse, Tina Wong, Denise Brooks, J. Auman, S. Balu, T. Bodenheimer, D. Hayes, A. Hoyle, S. Jefferys, Corbin D. Jones, S. Meng, P. Mieczkowski, Lisle E. Mose, C. Perou, Amy H. Perou, J. Roach, Yan Shi, J. Simons, Tara J. Skelly, Matthew G. Soloway, Donghui Tan, Umadevi Veluvolu, J. Parker, M. Wilkerson, Anil Korkut, Y. Şenbabaoğlu, P. Burch, R. McWilliams, K. G. Chaffee, A. Oberg, Wei Zhang, M. Gingras, D. Wheeler, Liu Xi, Monique Albert, J. Bartlett, H. Sekhon, Y. Stephen, Zaren Howard, M. Judy, A. Breggia, R. Shroff, Sudha Chudamani, Jia Liu, Laxmi Lolla, R. Naresh, T. Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Smith Jennifer, K. Roggin, K. Becker, M. Behera, Joseph Bennett, L. Boice, E. Burks, C. G. C. Júnior, J. Chabot, D. Tirapelli, J. S. Santos, M. Dubina, J. Eschbacher, Meijuan Huang, L. Huelsenbeck-Dill, R. Jenkins, A. Karpov, R. Kemp, V. Lyadov, S. Maithel, G. Manikhas, E. Montgomery, H. Noushmehr, A. Osunkoya, T. Owonikoko, O. Paklina, O. Potapova, S. Ramalingam, W. Rathmell, K. Rieger-Christ, Charles Saller, G. Setdikova, A. Shabunin, G. Sica, T. Su, T. Sullivan, P. Swanson, Katherine Tarvin, M. Tavobilov, L. Thorne, S. Urbanski, Olga Voronina, Timothy C. Wang, D. Crain, Erin E. Curley, J. Gardner, D. Mallery, S. Morris, J. Paulauskis, R. Penny, C. Shelton, T. Shelton, K. Janssen, O. Bathe, N. Bahary, J. Slotta-Huspenina, A. Johns, H. Hibshoosh, R. Hwang, A. Sepulveda, Amie Radenbaugh, S. Baylin, Mario Berrios, Moiz Bootwalla, Andrea E Holbrook, Phillip H. Lai, D. Maglinte, S. Mahurkar, T. Triche, D. V. Berg, D. Weisenberger, L. Chin, R. Kucherlapati, M. Kucherlapati, A. Pantazi, P. Park, Douglas Voet, Pei Lin, S. Frazer, T. DeFreitas, S. Meier, S. Kwon, Y. Kim, Sang Jae Park, Sung-Sik Han, S. Kim, H. Kim, E. Furth, M. Tempero, C. Sander, A. Biankin, D. Chang, Peter Bailey, A. Gill, J. Kench, S. Grimmond, R. Postier, R. Zuna, H. Sicotte, John A. Demchok, M. Ferguson, C. Hutter, K. Shaw, Margi Sheth, H. Sofia, R. Tarnuzzer, Zhining Wang, Liming Yang, J. Zhang, Ina Felau, J. Zenklusen +265 moresemanticscholar +1 more sourceIntegrative Proteomic Characterization of Human Lung Adenocarcinoma
Cell, 2020 Junming Xu, Chunchao Zhang, Xiang Wang, Linhui Zhai, Yiming Ma, Y. Mao, Kun Qian, Changqing Sun, Zhiwei Liu, Shangwen Jiang, Minghui Wang, Lin Feng, Lei Zhao, Ping Liu, Bo Wang, Xin Zhao, Hui Xie, Xiaoyun Yang, Liyuan Zhao, Yafei Chang, Jin-hui Jia, Xijun Wang, Yimin Zhang, Yaru Wang, Yikun Yang, Zhixiang Wu, Longhai Yang, Bin Liu, Teng Zhao, Shengguo Ren, A. Sun, Yang Zhao, W. Ying, Fei Wang, Guangshun Wang, Yi Zhang, Shujun Cheng, J. Qin, X. Qian, Yi Wang, Jing Li, F. He, T. Xiao, Minjia Tan +43 moresemanticscholar +1 more sourceMitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis
Advanced Materials, Volume 37, Issue 13, April 2, 2025.A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng +10 morewiley +1 more sourceZinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing
Advanced Materials, EarlyView.A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...Yedong Ma, Chengke Xie, Chengyu Liao, Binting Huang, Siqi Liu, Junhua Kong, Xiaotong Fan, Zibiao Li, Shi Chen, Chaobin He +9 morewiley +1 more sourceBioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars
Advanced Materials, EarlyView.Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.Juan José Esteve‐Moreno, Andrea Escudero, Oscar Ferreira Silvestre, José Manuel Terrés, Mónica Gorbe, Eva Garrido, Carlos Renero‐Lecuna, Judith Langer, María Alfonso, Javier Ibañez, Félix Sancenón, Roberto Cao‐Milán, Luis M. Liz‐Marzán, Alba García‐Fernández, Andy Hernández‐Montoto, Ramón Martínez‐Máñez +15 morewiley +1 more source
