Results 241 to 250 of about 1,279,856 (386)

Tumor-to-Tumor Metastasis: Breast Cancer Metastasizing to EGFR Exon 19-Mutated Lung Adenocarcinoma with Long-Term Disease-Free Survival. [PDF]

Biologics
Zhang Y, Hao Y, Yang H, Meng X, Yang S, Wang J, Xie J, Lu P, Ji Y.   +8 more
europepmc   +1 more source

A functional methylation signature to predict the prognosis of Chinese lung adenocarcinoma based on TCGA

, 2021
Ke Wang, Ying Liu, Guanzhong Lu, Jinrong Xiao, Jiao Huang, Lin Lei, Ji Peng, Yangkai Li, Sheng Wei   +8 more
openalex   +1 more source

METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression

Advanced Science, EarlyView.
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan, Huiwen Zhou, Jingsong Ma, Chensong Zhang, Yuhua Tan, Baoding Zhang, Jiabao Zhao, Ao Cheng, Chengyu Yang, Meijuan Xu, Shengyi Zhou, Yubo Xiong, Zeyang Lin, Guangchao Pan, Wenjie Ye, Mengya Zhong, Yang Yang, Yifan Zhuang, Shao‐Wei Li, Xianming Deng, Xuehui Hong   +20 more
wiley   +1 more source

Revealing Causal Protein Biomarkers and Potential Therapeutic Targets for Histologic-Specific Lung Cancer. [PDF]

J Cell Mol Med
Sun W, Liu J, Li J, Li N, Zhang X, Li C, Zhang L, He Y, Wu L, Wang X, Ji J, Zheng D.   +11 more
europepmc   +1 more source

AKR7A3 modulates the metastasis of pancreatic ductal adenocarcinoma through regulating PHGDH‐suppressed autophagy

, 2023
Lei Hua, Yang Song, Jie Min, Ronglin Wang, Hong Li, Liaoliao Zhu, Yongdong Guo, Dongxue Gan, Shanshan Li, Peixiang Ma, Cheng Yang, Jing Yang, Jingjie Shi, Junqiang Li, Haichuan Su   +14 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

PER3 suppresses lung adenocarcinomatous cell proliferation/migration through activating AMPK/mTOR pathway. [PDF]

Sci Rep
Yuan G, Liu Y, Wu D, Xu J.
europepmc   +1 more source

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.

Cancer Cell, 2014
A. Rhim, A. Rhim, P. Oberstein, Dafydd H. Thomas, Emily T Mirek, Carmine F. Palermo, Stephen A. Sastra, Erin N Dekleva, T. Saunders, Claudia P Becerra, I. Tattersall, C. B. Westphalen, J. Kitajewski, Maite G. Fernández-Barrena, M. Fernandez-Zapico, C. Iacobuzio-Donahue, K. Olive, B. Stanger   +17 more
semanticscholar   +1 more source

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

Advanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan, Mingyang Xiao, Liang Zhang, Shen Wang, Jiahang Wu, Kang Cao, Yujin Li, Guopei Zhang, Junwei Xie, Xiaobo Lu   +9 more
wiley   +1 more source

Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed‐Type Thyroid Cancer

Advanced Science, EarlyView.
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang, Jian Qi, Jialiang Wang, Zhipeng Wang, Yongguang Wang, Zongtao Hu, Ao Xu, Bo Hong, Hongzhi Wang   +8 more
wiley   +1 more source