Results 241 to 250 of about 672,479 (309)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Exceptional Response of HER2-Positive Breast Cancer to Osimertinib: A Case Report. [PDF]

Thorac Cancer
Yasui H, Hatasa M, Ohara K, Sano K, Mori Y, Shibata T, Fukui Y, Odate M, Arai Y, Fujii M, Makino Y.   +10 more
europepmc   +1 more source

Corynoxine Inhibits Tumor Growth via Targeting NQO1 and Modulating the PTPA–NQO1/PP2A Switch to Activate PP2A

Advanced Science, EarlyView.
Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou, Li Lin, Mengjie Xia, Ruohan Liang, Yueyue Zhang, Linna Du, Xuan Cao   +6 more
wiley   +1 more source

Radiation-Associated Enteric-Type Urethral Adenocarcinoma 20 Years After Prostate Brachytherapy: A Case Treated With Neoadjuvant Gemcitabine-Cisplatin and Robot-Assisted Radical Cystectomy. [PDF]

IJU Case Rep
Tanaka Y, Fujimura Y, Morishita K, Kashiwagi Y, Katsuno S, Nagai T, Okumura Y.   +6 more
europepmc   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source

Acute cholecystitis revealing gastric adenocarcinoma with osseous metastasis: a case report and review of the literature. [PDF]

Int J Surg Case Rep
Jidou AV, Aberkane M, Guellil A, Jabi R, Bennani A, Bouziane M.   +5 more
europepmc   +1 more source

Refractory Pruritus in End-Stage Prostatic Adenocarcinoma: An Unusual Presentation of A Hypereosinophilic Syndrome. [PDF]

Eur J Case Rep Intern Med
Lorusso L, Bovello MV, Cavagna M, Mare M, Caimi C, Fusi-Schmidhauser T.   +5 more
europepmc   +1 more source

When Prostate Cancer Mimics Multiple Myeloma: Diffuse Bone Marrow Infiltration Revealing Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation. [PDF]

Cureus
Lamine L, Senoussi C, Nadif L, Bennour S, Mokfi R, Berrada NN, Bouhou I, Meryam L, Boutaagount F, Maskrout M, Rais G.   +10 more
europepmc   +1 more source

Surgical Intervention and Treatment of a Mammary Adenocarcinoma in the Sugar Glider (<i>Petaurus breviceps</i>): A Double Case Report. [PDF]

Case Rep Vet Med
Peña T, Tormollen Z.
europepmc   +1 more source

Atypical Spread With Lung Shrinkage and Cystic Changes in Bilateral Lepidic Adenocarcinoma. [PDF]

Respirol Case Rep
Takiguchi H, Ito Y, Kajiwara H, Kobayashi M, Oguma T.   +4 more
europepmc   +1 more source