Results 241 to 250 of about 1,201,752 (348)

Primary Hepatoid Adenocarcinoma of the Lung With Signet Ring Cell Differentiation and Widespread Osseous Metastases: A Case Report. [PDF]

Respirol Case Rep
Khader R, Elhakim E, Bdair M, Sultan RA, Khader A, Almasalma M, Ferwana S, Baraka MZA.   +7 more
europepmc   +1 more source

MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.

Journal of the American Medical Association (JAMA), 2008
Aaron J Schetter, S. Leung, Jane J. Sohn, Krista A. Zanetti, E. Bowman, N. Yanaihara, S. Yuen, T. Chan, D. Kwong, G. Au, Chang-Gong Liu, G. Calin, C. Croce, C. Harris   +13 more
semanticscholar   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

The risk of neoplasms in appendiceal abscess: what emergency surgeons should know. [PDF]

Front Oncol
Montori G, Podda M, Giordano A, Procida G, Butera V, Murzi V, Fugazzola P, Bergamini C, Catena F, Ansaloni L, Pisanu A, Agresta F.   +11 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Atypical Presentation of a Malignant Tumor of the Appendix: A Case Report. [PDF]

Cureus
Garcia Ramírez MH, Zepeda Torres JM, Suárez Carreón LO, Alegría López LB, Íñiguez Muñoz E, Hernández Ramírez R, Murrieta Vallejo JJ, Ulloa Ulloa VM, Ángel Montoya DA, García González JG.   +9 more
europepmc   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Diagnostic utility of tumor volume doubling time in ciliated muconodular papillary tumor/bronchiolar adenoma mimicking invasive mucinous adenocarcinoma: A case report. [PDF]

Radiol Case Rep
Oki T, Iizuka S, Otsuki Y, Nakamura T.
europepmc   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source