Topoisomerase II binding protein 1-interacting checkpoint and replication regulator promotes lung adenocarcinoma proliferation by regulating myelocytomatosis oncogene signaling pathway. [PDF]
Zhao Y, Feng Y, Guo M, Li L.
europepmc +1 more source
Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression
This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng +8 more
wiley +1 more source
External validation of the graded prognostic assessment for patients with non-small cell lung cancer and brain metastases using molecular markers (Lung-molGPA). [PDF]
Hong SW, Jeon W, Kim JS, Song C.
europepmc +1 more source
Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao +14 more
wiley +1 more source
Case Report: Prostate adenocarcinoma with peritoneal carcinomatosis and elevated CEA mimicking colorectal cancer: a diagnostic dilemma. [PDF]
Majeed H +6 more
europepmc +1 more source
Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie +17 more
wiley +1 more source
Lung Adenocarcinoma Promotes NETosis via the NPM1-TNFAIP6-CD44-SPP1 Axis. [PDF]
Liu R +7 more
europepmc +1 more source
Infective Endocarditis in Disseminated <i>Streptococcus dysgalactiae</i> Infection Originating From Hitherto Undetected Colorectal Adenocarcinoma. [PDF]
Meeus R +4 more
europepmc +1 more source
Primary Apocrine Adenocarcinoma of the Vulva: A Report of a Rare Case. [PDF]
Yoakam M +6 more
europepmc +1 more source
Diagnostic importance of serum markers in lung cancer. [PDF]
Liang Q +5 more
europepmc +1 more source

