Results 131 to 140 of about 478,988 (359)

1424 m⁶A regulators related to molecular feature, immune microenvironment and prognosis in lung adenocarcinoma [PDF]

, 2022
Zhibo Tan, Min Chen, Yujie Zhao, Feng Peng, Ying Li, Mengqi Yang, Lei Zhang, Xin Li, Pengfei Yang, Zhe Zhang, Daming Li, Zhaoming Peng, Yajie Liu   +12 more
openalex   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Coxsackievirus Type B3 Is a Potent Oncolytic Virus against KRAS-Mutant Lung Adenocarcinoma

Molecular Therapy: Oncolytics, 2019
KRAS mutant (KRASmut) lung adenocarcinoma is a refractory cancer without available targeted therapy. The current study explored the possibility to develop coxsackievirus type B3 (CVB3) as an oncolytic agent for the treatment of KRASmut lung ...
Haoyu Deng, Huitao Liu, Tanya de Silva, YuanChao Xue, Yasir Mohamud, Chen Seng Ng, Junyan Qu, Jingchun Zhang, William W.G. Jia, William W. Lockwood, Honglin Luo   +10 more
doaj   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Membranous nephropathy in a patient with pulmonary tuberculosis infection and lung adenocarcinoma: a case report

, 2021
Nobuhisa Morimoto, Kiyotaka Nagahama, Yukio Tsuura, Ayumi Terai, Madoka Tanabe, Megumi Otani, Shingo Shioji, Suguru Hirasawa, Shota Aki, Makoto Aoyagi, Hiroyuki Tanaka   +10 more
openalex   +2 more sources

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Attribution of ghrelin to cancer; Attempts to unravel an apparent controversy [PDF]

, 2019
Ghrelin is an endogenous peptide hormone mainly produced in the stomach. It has been known to regulate energy homeostasis, stimulate secretion of growth hormone, and mediate many other physiologic effects. Various effects attributed to ghrelin contribute
Khani, Leila, Pastaki Khoshbin, Amin, Roosta, Venus, Sadeghi, Fatemeh, Soleyman-Jahi, Saeed, Zendehdel, Kazem   +5 more
core   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Cushing's Syndrome in Adenocarcinoma of Lung Responding to Osilodrostat. [PDF]

Case Rep Oncol, 2023
Heleno CT, Hong SPD, Cho HG, Kim MJ, Park Y, Chae YK.   +5 more
europepmc   +1 more source

Utility of five commonly used immunohistochemical markers TTF‐1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases [PDF]

, 2015
Grzegorz T. Gurda, Lei Zhang, Yuting Wang, Li Chen, Susan Geddes, William C. Cho, Frederic B. Askin, Edward Gabrielson, Qing Kay Li   +8 more
openalex   +1 more source