Results 211 to 220 of about 298,027 (258)

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

open access: yesBMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan   +8 more
wiley   +1 more source
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Spectrum of Lung Adenocarcinoma

Seminars in Ultrasound, CT and MRI, 2019
Lung cancer remains the most common cause of cancer death in the United States of America and worldwide despite continued advances in lung cancer screening as well as surgical, medical, and radiation oncological treatments. Adenocarcinoma is the most common histological subtype of primary lung cancer and has recently been reorganized into a spectrum ...
Barry D, Hutchinson   +3 more
openaire   +2 more sources

Multicentricity of Adenocarcinoma of the Lung

Chest, 1989
In a consecutive series of 62 lung resections for bronchogenic adenocarcinoma, 12 patients (19 percent) were found to have two or more adenocarcinomas on careful pathologic examination. These tumors all met the criteria for separate primary malignancy. In only two of the patients were the additional lesions suspected preoperatively.
G, McElvaney   +5 more
openaire   +2 more sources

Hepatoid adenocarcinoma in the lung

Lung Cancer, 2002
We have experienced a very rare case of hepatoid adenocarcinoma in the lung. A 55-year-old male with a history of smoking was diagnosed as adenocarcinoma of the right S2, and underwent resection of the right upper lobe and dissection of the hilum and mediastinal lymph nodes (complete resection).
Yasufumi, Hayashi   +4 more
openaire   +2 more sources

Giant cell adenocarcinoma of the lung

Cancer, 1966
The 63 giant cell adenocarcinomas of the lung which were found among 592 primary lung carcinomas in 25,785 necropsies during the period from 1945 through 1957 at the Los Angeles County Hospital were studied in detail by histochemical methods. These tumors constitute 10.3% of the primary pulmonary lung carcinomas in this group.
D L, Herman, W K, Bullock, J K, Waken
openaire   +2 more sources

RISK FACTORS FOR ADENOCARCINOMA OF THE LUNG

American Journal of Epidemiology, 1987
The relation between various risk factors and adenocarcinoma of the lung was evaluated in a case-control study. Subjects were selected from the Colorado Central Cancer Registry from 1979-1982 in the Denver metropolitan area. A total of 102 (50 males and 52 females) adenocarcinoma case interviews and 131 (65 males and 66 females) control interviews were
R C, Brownson   +4 more
openaire   +2 more sources

Rare subtypes of adenocarcinoma of the lung

Expert Review of Anticancer Therapy, 2011
The 1999 WHO classification of adenocarcinoma of the lung and pleural tumors listed five rare variants of adenocarcinoma of the lung: well-differentiated fetal adenocarcinoma, colloid 'mucinous' adenocarcinoma, mucinous cystadenocarcinoma, signet ring adenocarcinoma and clear-cell adenocarcinoma.
Ou, S.-H.I.   +3 more
openaire   +2 more sources

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