Results 221 to 230 of about 284,151 (314)
Elevated Expression of Interleukins in Lung Adenocarcinomas Induced by N‐Nitrosobis(2‐hydroxypropyl)amine in Rats [PDF]
Toshifumi Tsujiuchi+3 more
openalex +1 more source
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han+16 more
wiley +1 more source
Mutations and Reduced Expression of the Transforming Growth Factor‐β Receptor II Gene in Rat Lung Adenocarcinomas Induced by N‐Nitrosobis‐(2‐hydroxypropyl)amine [PDF]
Toshifumi Tsujiuchi+3 more
openalex +1 more source
Advanced Microfluidics for Single Cell‐Based Cancer Research
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro+10 more
wiley +1 more source
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen+13 more
wiley +1 more source
Non-bacterial cystitis caused by pembrolizumab therapy for adenocarcinoma of the lung: a case report. [PDF]
Di C, Yu T, Ni L.
europepmc +1 more source