Results 31 to 40 of about 284,151 (314)

EGFR Mutation Status in Uighur Lung Adenocarcinoma Patients

Chinese Journal of Lung Cancer, 2013
Background and objective Epidermal growth factor receptor (EGFR), a transmembrane protein, is a member of the tyrosine kinase family. Gefitinib, an EGFR tyrosine-kinase inhibitors, has shown a high response rate in the treatment of lung cancer in ...
Li SHAN, Yan ZHANG, Feng ZHAO, Limou ZHENG, Guoqing ZHANG   +4 more
doaj   +1 more source

DEPDC1 is Highly Expressed in Lung Adenocarcinoma and Promotes Tumor Cell Proliferation

Chinese Journal of Lung Cancer, 2021
Background and objective Lung cancer is the leading cause of death worldwide, and lung adenocarcinoma is the main subtype of lung cancer. DEP domain-containing 1 (DEPDC1) has been proved to be closely related to the occurrence and development of most ...
Jian SHEN, Mengmeng XI
doaj   +1 more source

Invasive mucinous adenocarcinoma of the lung [PDF]

Translational Cancer Research, 2019
Invasive mucinous adenocarcinoma (IMA) is a unique histological subtype of adenocarcinoma. Due to its low incidence rates, survival data for IMA is scarce and often contradictory. The clinical manifestations of IMA are not precise as compared to other adenocarcinomas, with some patients having bronchial mucus overflow. Difference in immunohistochemical
Chenghui Li, Hongyang Lu, Lu Xu
openaire   +3 more sources

GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma

BMC Cancer, 2018
Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei, Kun Zhang, Haifeng Qin, Jinlong Zhu, Qiaoxi Qin, Yang Yu, Hong Wang   +6 more
doaj   +1 more source

Progesterone/Org inhibits lung adenocarcinoma cell growth via membrane progesterone receptor alpha

Thoracic Cancer, 2020
Background The aim of this study was to determine whether progesterone could inhibit the growth of lung adenocarcinoma cells via membrane progesterone receptor alpha (mPRα) and elucidate its potential mechanism.
Jian Xiao, Xi Chen, Xiaoxiao Lu, Mingxuan Xie, Bixiu He, Shuya He, Shaojin You, Qiong Chen   +7 more
doaj   +1 more source

Long noncoding RNA expression profiles of lung adenocarcinoma ascertained by microarray analysis. [PDF]

PLoS ONE, 2014
BACKGROUND:Long noncoding RNAs (lncRNAs) have been shown to be involved in the development and progression of lung cancer. However, the roles of lncRNAs in lung cancer are not well understood.
Gang Xu, Jie Chen, Qinshi Pan, Keta Huang, Jingye Pan, Wenhui Zhang, Jian Chen, Fangyou Yu, Tieli Zhou, Yumin Wang   +9 more
doaj   +1 more source

Overexpression of RhoV Promotes the Progression and EGFR-TKI Resistance of Lung Adenocarcinoma

Frontiers in Oncology, 2021
BackgroundThe Rho GTPase family with ~20 member genes play central roles in a wide variety of cellular processes and tumor cell migration and metastasis.
Hongjin Chen, Ruixue Xia, Long Jiang, Yong Zhou, Haojun Xu, Weiwei Peng, Chengyun Yao, Guoren Zhou, Yijie Zhang, Hongping Xia, Hongping Xia, Hongping Xia, Yongsheng Wang   +12 more
doaj   +1 more source

Papillary Adenocarcinoma: A Rare Subtype of Lung Adenocarcinoma

Cureus, 2023
Papillary adenocarcinoma (PA) of the lung is a specific form of lung cancer characterized by papillary structures in tumor cells. This type of cancer is relatively rare and has distinct pathological and radiological features that differentiate it from other types of lung adenocarcinomas.
Thouil, Afaf, Ramdani, Abdelbassir, Rhazari, Meriem, Marouf, Rachid, Kouismi, Hatim   +4 more
openaire   +2 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source