Results 51 to 60 of about 436,688 (335)

Adenocarcinoma of the lung mimicking interstitial lung disease

Gülhane Tıp Dergisi
Atypical radiologic and clinical patterns may be observed within subgroups of lung adenocarcinoma. A 74-year-old man with progressive dyspnea and productive cough unresponsive to antibiotherapy showed bilateral interstitial changes in the lung parenchyma
Sümeyye Kodalak Cengiz, Nesrin Kıral, Tamer Baysal, Gonca Gül Geçmen   +3 more
doaj   +1 more source

Naked Cuticle Drosophila 1 Expression in Histologic Subtypes of Small Adenocarcinoma of the Lung

The Korean Journal of Pathology, 2013
Background Naked cuticle Drosophila 1 (NKD1) has been related to non-small cell lung cancer in that decreased NKD1 levels have been associated with both poor prognosis and increased invasive quality.
Sangjeong Ahn, Won Hwangbo, Hyunchul Kim, C. Kim   +3 more
semanticscholar   +1 more source

Progesterone/Org inhibits lung adenocarcinoma cell growth via membrane progesterone receptor alpha

Thoracic Cancer, 2020
Background The aim of this study was to determine whether progesterone could inhibit the growth of lung adenocarcinoma cells via membrane progesterone receptor alpha (mPRα) and elucidate its potential mechanism.
Jian Xiao, Xi Chen, Xiaoxiao Lu, Mingxuan Xie, Bixiu He, Shuya He, Shaojin You, Qiong Chen   +7 more
doaj   +1 more source

Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming. [PDF]

, 2016
The impact of EGFR-mutant NSCLC precision therapy is limited by acquired resistance despite initial excellent response. Classic studies of EGFR-mutant clinical resistance to precision therapy were based on tumor rebiopsies late during clinical tumor ...
Bagai, Rakesh, Bivona, Trever G, Danielpour, David, Feng, Yan, Leahy, Patrick, Lindner, Daniel, Ma, Patrick C, Rosell, Rafael, Shi, Ivy, Thiagarajan, Praveena S, Veigl, Martina, Wu, Xiaoliang, Yin, Lihong, Zhang, Wei, Zhang, Zhenfeng   +14 more
core   +1 more source

GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma

BMC Cancer, 2018
Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei, Kun Zhang, Haifeng Qin, Jinlong Zhu, Qiaoxi Qin, Yang Yu, Hong Wang   +6 more
doaj   +1 more source

DEPDC1 is Highly Expressed in Lung Adenocarcinoma and Promotes Tumor Cell Proliferation

Chinese Journal of Lung Cancer, 2021
Background and objective Lung cancer is the leading cause of death worldwide, and lung adenocarcinoma is the main subtype of lung cancer. DEP domain-containing 1 (DEPDC1) has been proved to be closely related to the occurrence and development of most ...
Jian SHEN, Mengmeng XI
doaj   +1 more source

Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer. [PDF]

, 2015
The cancer stem cell hypothesis, that a small population of tumour cells are responsible for tumorigenesis and cancer progression, is becoming widely accepted and recent evidence has suggested a prognostic and predictive role for such cells. Intra-tumour
Banerji, CR, Caldas, C, Severini, S, Teschendorff, AE   +3 more
core   +3 more sources

Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance. [PDF]

, 2018
Expression of the chromatin-associated protein HMGA2 correlates with progression, metastasis and therapy resistance in pancreatic ductal adenocarcinoma (PDAC). Hmga2 has also been identified as a marker of a transient subpopulation of PDAC cells that has
Chiou, Shin-Heng, Dorsch, Madeleine, Grüner, Barbara M, Koong, Albert C, Kozak, Margaret M, Kusch, Eva, Naranjo, Santiago, Winslow, Monte M   +7 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Long noncoding RNA expression profiles of lung adenocarcinoma ascertained by microarray analysis. [PDF]

PLoS ONE, 2014
BACKGROUND:Long noncoding RNAs (lncRNAs) have been shown to be involved in the development and progression of lung cancer. However, the roles of lncRNAs in lung cancer are not well understood.
Gang Xu, Jie Chen, Qinshi Pan, Keta Huang, Jingye Pan, Wenhui Zhang, Jian Chen, Fangyou Yu, Tieli Zhou, Yumin Wang   +9 more
doaj   +1 more source