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An Electron Microscope Study of Islet Cell Adenomas

JAMA: The Journal of the American Medical Association, 1963
THE ULTRASTRUCTURAL characteristics of the islet cells of the pancreas are sufficiently different to permit identification of cell types without recourse to the selective staining methods required for light microscopy.1-3Such tinctorial methods often fail to indicate the cell type present in pancreatic tumors.
M H, GREIDER   +2 more
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Functioning Pancreatic Islet Cell Adenoma

Archives of Internal Medicine, 1963
Cochrane, Payne, Simpkiss, and Wolff first described in 1956 1 a type of hypoglycemia in infants which was precipitated or aggravated by feedings containing L-leucine. Approximately 60 children with this familial disorder have been reported. 2 Weisenfeld and Goldner recently reviewed the incidence ofL-leucine sensitivity in adults.
J, BUSE   +4 more
openaire   +3 more sources

The effect of diazoxide in children with islet cell adenomas

Clinical Biochemistry, 1973
1. Three children diagnosed preoperatively as having islet cell adenoma of the pancreas were studied. Only one of them exhibited hyperinsulinism during a provocative test. In the remaining two patients the diagnosis was made on the basis of an inappropriately high insulin/glucose ratio during hypoglycemia (relative hyperinsulinemia).
A, Castro, K, Dyess, N, Buist, J, Potts
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Islet cell adenoma presenting as a psychiatric problem

The Irish Journal of Medical Science, 1958
The British literature on spontaneous hyperinsulinism due to islet cell neoplasms is reviewed with reference to the psychiatric presentation of the disease. Two further cases of islet cell adenoma which were diagnosed in a psychiatric hospital are described. Of the total 39 patients, 7 were diagnosed in a psychiatric hospital, 1 of them at post mortem.
D J, DOORLY, E A, MARTIN
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Hypoglycemia due to pancreatic islet cell adenoma

The Journal of Pediatrics, 1962
Summary Two cases of pancreatic islet cell adenoma are described, one in a newborn female, the other in a 6-year-old girl, bringing to 27 the number of reported cases in children. Apart from the demonstration of persistent hypoglycemia, extensive biochemical studies in the older child revealed normal function of pancreas, other endocrine glands, and ...
R, FRANCOIS   +3 more
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ISLET CELL ADENOMA IN CHILDHOOD: REPORT OF A CASE

Pediatrics, 1967
The case of an 11-year-old boy with multiple islet cell adenoma of the pancreas is described. The case is of particular interest because the mild and infrequent symptoms resulted in an incorrect diagnosis of a primary convulsive disorder. The problems of accurate pre-operative diagnosis, despite the availability of all current diagnostic studies, are ...
A, Drash, R, Schultz
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Bilateral Pheochromocytoma and Islet Cell Adenoma of the Pancreas

Archives of Surgery, 1982
An 18-year-old woman with bilateral pheochromocytomas and an asymptomatic islet cell adenoma of the pancreas represents the 11th patient to be described with this combination of endocrine tumors. No other components of any multiple endocrine adenomatosis (MEA) syndromes were present.
J R, Zeller   +3 more
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Islet Cell Adenoma in Newborn

Pediatrics, 1968
The article by Salinas, et al., "Functioning Islet Cell Adenoma in the Newborn," in the March issue of Pediatrics (41:646, 1968) raises a number of questions. If the adenoma was the cause of the hypoglycemia, I am at a loss to explain the mechanism. There was no increase in peripheral venous insulin, as well as no increase in portal vein
openaire   +1 more source

NEONATAL HYPOGLYCAEMIA DUE TO AN ISLET‐CELL ADENOMA

Acta Paediatrica, 1973
SummaryA full‐term newborn showed signs of hypogly‐caemia which was very resistant to treatment. At the age of 4 months the child underwent an explorative laparotomy. An adenoma was found in the pancreas and was enucleated. The insulin content of the adenoma was extremely high.
openaire   +2 more sources

Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes

Cell Metabolism, 2020
Joan Camunas-Soler   +2 more
exaly  

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