The Cells of the Islets of Langerhans [PDF]
Journal of Clinical Medicine, 2018 Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non-β islet cells in to insulin-producing β-cells to replenish β-cell mass as a means to treat diabetes.
Gabriela da Silva Xavier
exaly +6 more sources
Azelaic acid reduces arsenic-induced toxicity and inflammation in the rat islets of langerhans [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Arsenic is classified as a toxic metal that is naturally found in the Earth’s crust, and long-term exposure to it can result in chronic human disorders like cancer and diabetes.
Sara Mostafalou +4 more
doaj +2 more sources
In vitro effect of bioscaffolds on viability and insulin‑producing function of human islets of Langerhans [PDF]
Вестник трансплантологии и искусственных органов, 2022 The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva +3 more
doaj +2 more sources
A Tissue-Engineered Construct Based on a Decellularized Scaffold and the Islets of Langerhans: A Streptozotocin-Induced Diabetic Model [PDF]
LifeProducing a tissue-engineered pancreas based on a tissue-specific scaffold from a decellularized pancreas, imitating the natural pancreatic tissue microenvironment and the islets of Langerhans, is one of the approaches to treating patients with type 1 ...
Victor I. Sevastianov +12 more
doaj +2 more sources
Potential of [11C]UCB-J as a PET tracer for islets of Langerhans [PDF]
Scientific Reports, 2021 Biomarkers for the measurement of islets of Langerhans could help elucidate the etiology of diabetes. Synaptic vesicle glycoprotein 2 A (SV2A) is a potential marker reported to be localized in the endocrine pancreas.
Emmi Puuvuori +5 more
doaj +2 more sources
Illuminating the complete ß-cell mass of the human pancreas- signifying a new view on the islets of Langerhans [PDF]
Nature CommunicationsTomas Alanentalo +2 more
exaly +2 more sources
Morphogenesis of the Islets of Langerhans Is Guided by Extraendocrine Slit2 and Slit3 Signals [PDF]
Molecular and Cellular Biology, 2021 Barak Blum, Jennifer M Gilbert
exaly +2 more sources
Biomedicines, 2022 Background: Previous studies have reported involvement of Toxoplasma gondii (T. gondii) infections in the pathogenesis of some autoimmune diseases, such as polymyositis, rheumatoid arthritis, autoimmune thyroiditis, and Crohn’s disease.
Asmaa M. El-kady +11 more
doaj +1 more source
Estrogens counteract tributyltin-induced toxicity in the rat islets of Langerhans [PDF]
Heliyon, 2020 Mohammad Abdollahi +2 more
exaly +2 more sources
BIO Web of Conferences, 2020 The concentration of glucose and glycosylated hemoglobin in the blood of animals increases as a result of physiological aging. This is due to damage to the pancreatic insular apparatus and a decrease in the number and functioning of active β-cells.
Klyueva Yulia +4 more
doaj +1 more source