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The Cells of the Islets of Langerhans [PDF]

open access: yesJournal of Clinical Medicine, 2018
Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non-β islet cells in to insulin-producing β-cells to replenish β-cell mass as a means to treat diabetes.
Gabriela Da Silva Xavier
exaly   +4 more sources

Transplantation or islets of Langerhans: new developments

open access: yesSwiss Medical Weekly, 2001
The clinical results recently reported by the Edmonton group in recipients of allogeneic islet grafts, all of whom achieved at least temporary insulin independence, has rekindled interest in transplantation of islets of Langerhans as a means to cure diabetes.
A Caulfield   +4 more
doaj   +3 more sources

Pancreatic Pathological Changes in Murine Toxoplasmosis and Possible Association with Diabetes Mellitus

open access: yesBiomedicines, 2022
Background: Previous studies have reported involvement of Toxoplasma gondii (T. gondii) infections in the pathogenesis of some autoimmune diseases, such as polymyositis, rheumatoid arthritis, autoimmune thyroiditis, and Crohn’s disease.
Asmaa M. El-kady   +11 more
doaj   +1 more source

In vitro effect of bioscaffolds on viability and insulin‑producing function of human islets of Langerhans

open access: yesВестник трансплантологии и искусственных органов, 2022
The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva   +3 more
doaj   +1 more source

Morphofunctional condition of the pancreatic insular apparatus in old rats with alloxan-induced diabetes and its correction with lipoic acid

open access: yesBIO Web of Conferences, 2020
The concentration of glucose and glycosylated hemoglobin in the blood of animals increases as a result of physiological aging. This is due to damage to the pancreatic insular apparatus and a decrease in the number and functioning of active β-cells.
Klyueva Yulia   +4 more
doaj   +1 more source

The combined effect of magnetic and electric fields using on/off infrared light on the blood sugar level and the diameter of Langerhans islets of diabetic mice [PDF]

open access: yesVeterinary World, 2020
Background and Aim: At present, diabetes is treated with oral antidiabetic medicines, such as sulfonylureas and thiazolidine, as well as insulin injection. However, these methods have several shortcomings.
S. Suhariningsih   +7 more
doaj   +1 more source

Effect of Juvenile Obesity on the Islets of Langerhans in Rat and the Possibility of Recovery at Adulthood: A Histological and Immunohistochemical Study [PDF]

open access: yesThe Egyptian Journal of Histology, 2021
Background: Juvenile obesity is a serious problem that increases the risk of future development of cardiovascular disease and type 2 diabetes at adulthood through programing a metabolic dysfunction during development.Aim of the Work: to perform a ...
Marwa Ibrahim   +2 more
doaj   +1 more source

Protecting islet functional viability using mesenchymal stromal cells

open access: yesStem Cells Translational Medicine, 2021
Islet transplantation is an emerging treatment for type 1 diabetes which offers the prospect of physiological control of blood glucose and reductions in acute hypoglycaemic episodes.
Ella L. Hubber   +2 more
doaj   +1 more source

Surface Coating of Islets of Langerhans by Activated Polyethylene Glycol [PDF]

open access: yesعلوم و تکنولوژی پلیمر, 2008
The final treatment for diabetes is transplantation of islets of Langerhans. One of the new proposed methods for immunological preservation of transplanted cells is coating of cell surface by polyethylene glycol.
S. Hashemi Najafabadi   +3 more
doaj   +1 more source

Differentiation of pancreatic endocrine islets in buffalo fetus

open access: yesIndian Journal of Animal Sciences, 2020
Pancreas of 24 buffalo foetii collected from abattoir and veterinary clinics, GADVASU, Ludhiana were studied. The buffalo foetii were divided into three groups after measuring their CVRL, viz.
DIVYA GUPTA   +3 more
doaj   +1 more source

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