Results 31 to 40 of about 24,397 (218)

HISTOMORPHOLOGICAL PECULIARITIES OF THE PANCREATIC PARENCHYMA IN RATS WITH ALLOXAN-INDUCED DIABETES OF DIFFERENT DURATION

open access: yesНеонатологія, хірургія та перинатальна медицина
The study of pathohistological and morphofunctional changes in the endocrine pancreas is an integral part of experimental diabetology, which allows obtaining a signifi cant amount of information on various aspects of the etiology and pathogenesis of ...
О. Оленович   +3 more
doaj   +1 more source

Entrapment of Cultured Pancreas Islets in Three-Dimensional Collagen Matrices

open access: yesCell Transplantation, 1992
In vitro culture of islets of Langerhans decreases their immunogenecity, presumably by eliminating passenger leukocytes and other Ia+ presenting cells within the islets.
Seh-Huang Chao   +3 more
doaj   +1 more source

Functional efficiency of pancreatic cell-engineered construct in an animal experimental model for type I diabetes

open access: yesВестник трансплантологии и искусственных органов
The creation of a cell-engineered pancreatic construct (CEPC) from islets of Langerhans and biocompatible matrix carrier (framework/scaffold), which imitates the native microenvironment of pancreatic tissue, is an approach to the treatment of type I ...
N. V. Baranova   +6 more
doaj   +1 more source

Langerhans Islets: cell composition and the importance of pancreatic hormones for the body [PDF]

open access: yes, 2022
Introducere. Insulele Langerhans reprezintă grupuri concentrice de celule endocrine care sunt dispersate în parenchimul pancreasului. Componenta endocrină a pancreasului are un rol primordial în reglarea proceselor metabolice, de aceea în ultimii ani tot
Calașnicov, Mădălina
core  

Cyclic AMP signalling in pancreatic islets

open access: yes, 2010
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Nigel J. Pyne   +7 more
core   +1 more source

Effect of Moderate-Intensity Continuous Training (MICT) on Pancreatic Islet of Langerhans’ Morphology and Cell Count of Female Rats (Rattus norvegicus) Exposed to High-Calorie Diet

open access: yesJuxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Introduction: Calorie consumption that exceeds normal limits each year can be a risk factor in causing diabetes mellitus (DM). This condition causes the body to be in a state of hyperglycemia, which will trigger changes in the diameter and number of ...
Eny Wulan Sari   +3 more
doaj   +1 more source

The distribution of the islets of Langerhans in pancreas of euglycemic spontaneously hypertensive rats

open access: yesPatologìâ, 2016
Considering the fact, that pancreatic beta cells are responsible for production of all insulin needed to maintain the glucose homeostasis, the problem of beta cells pull control in patients with hypertension is rather topical.
T. V. Abramova
doaj   +1 more source

The effect of ghrelin on Kiss-1 and KissR gene transcription and insulin secretion in rat islets of Langerhans and CRI-D2 cell line [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s): Ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. The central effects including GH secretion, food intake, and energy homeostasis are partly mediated by Kiss1- KissR signaling pathway. Ghrelin
Mandana Mahmoodzaeh Sagheb   +2 more
doaj   +1 more source

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Collection of islets of Langerhans using an equilibrium method

open access: yesBioTechniques, 2013
Here we present a convenient method for easy hand selection of enzymatically isolated small tissues such as islets of Langerhans. Islets are continuously collected in a micropipette tip connected to a peristaltic pump.
Duk-Su Koh, Mark Moody, Junghyo Jo
doaj   +1 more source

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