The Cells of the Islets of Langerhans [PDF]
Journal of Clinical Medicine, 2018 Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non-β islet cells in to insulin-producing β-cells to replenish β-cell mass as a means to treat diabetes.
Gabriela da Silva Xavier
exaly +4 more sources
The combined effect of magnetic and electric fields using on/off infrared light on the blood sugar level and the diameter of Langerhans islets of diabetic mice [PDF]
Veterinary World, 2020 Background and Aim: At present, diabetes is treated with oral antidiabetic medicines, such as sulfonylureas and thiazolidine, as well as insulin injection. However, these methods have several shortcomings.
S. Suhariningsih +7 more
doaj +2 more sources
Upconverting Nanoparticles for Bimodal Luminescence and Magnetic Resonance Imaging of Langerhans Islets [PDF]
Small ScienceCombining luminescence with magnetic resonance imaging (MRI) is a noninvasive approach that significantly improves detection sensitivity and diagnostic precision for severe diseases. In diabetes care, this approach considerably broadens the possibilities
Oleksandr Shapoval +9 more
doaj +2 more sources
IAPP/amylin deposition, which is correlated with expressions of ASC and IL-1β in β-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation [PDF]
International Journal of Immunopathology and Pharmacology, 2018 Recent findings revealed that type 2 diabetes mellitus (T2D) is a chronic inflammatory disease and an islet amyloid polypeptide (IAPP)/amylin, is deposited within pancreatic islets.
Shinnosuke Morikawa +9 more
doaj +2 more sources
Prediction of Pancreatic Islet Yield After Pancreatectomy Using Optical Coherence Elastography [PDF]
DiagnosticsIntraoperative assessment of pancreatic quality, followed by sampling for the potential isolation of Langerhans islets for subsequent autotransplantation, is currently a key component of post-total pancreatectomy diabetes mellitus treatment.
Ekaterina Gubarkova +11 more
doaj +2 more sources
Biomedicines, 2022 Background: Previous studies have reported involvement of Toxoplasma gondii (T. gondii) infections in the pathogenesis of some autoimmune diseases, such as polymyositis, rheumatoid arthritis, autoimmune thyroiditis, and Crohn’s disease.
Asmaa M. El-kady +11 more
doaj +1 more source
Вестник трансплантологии и искусственных органов, 2022 The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva +3 more
doaj +1 more source
BIO Web of Conferences, 2020 The concentration of glucose and glycosylated hemoglobin in the blood of animals increases as a result of physiological aging. This is due to damage to the pancreatic insular apparatus and a decrease in the number and functioning of active β-cells.
Klyueva Yulia +4 more
doaj +1 more source
Effect of Juvenile Obesity on the Islets of Langerhans in Rat and the Possibility of Recovery at Adulthood: A Histological and Immunohistochemical Study [PDF]
The Egyptian Journal of Histology, 2021 Background: Juvenile obesity is a serious problem that increases the risk of future development of cardiovascular disease and type 2 diabetes at adulthood through programing a metabolic dysfunction during development.Aim of the Work: to perform a ...
Marwa Ibrahim +2 more
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Surface Coating of Islets of Langerhans by Activated Polyethylene Glycol [PDF]
علوم و تکنولوژی پلیمر, 2008 The final treatment for diabetes is transplantation of islets of Langerhans. One of the new proposed methods for immunological preservation of transplanted cells is coating of cell surface by polyethylene glycol.
S. Hashemi Najafabadi +3 more
doaj +1 more source