Results 21 to 30 of about 21,208 (178)
Pharmaceutics, 2021 The platform for precise proteomic profiling of targeted cell populations from heterogeneous tissue sections is developed. We demonstrate a seamless and systematic integration of LCM with an automated cap-IA for the handling of a very small-sized ...
Shashank Pandey +5 more
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The Islets of Langerhans in Relation to Diabetes [PDF]
Biochemical Journal, 1907 The work recorded in the following paper was undertaken with a view to testing the hypothesis frequently brought forward that the islets of Langerhans of the pancreas yield an internal secretion whose function has some relation to the utilization of dextrose in the vertebrate organism. The primary cause of diabetes is, according to Macleod,1 the ' want
J, Rennie, T, Fraser
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Неонатологія, хірургія та перинатальна медицинаThe study of pathohistological and morphofunctional changes in the endocrine pancreas is an integral part of experimental diabetology, which allows obtaining a signifi cant amount of information on various aspects of the etiology and pathogenesis of ...
О. Оленович +3 more
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Entrapment of Cultured Pancreas Islets in Three-Dimensional Collagen Matrices
Cell Transplantation, 1992 In vitro culture of islets of Langerhans decreases their immunogenecity, presumably by eliminating passenger leukocytes and other Ia+ presenting cells within the islets.
Seh-Huang Chao +3 more
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مجله دانشکده پزشکی اصفهان, 2020 Background: Diabetes is caused by a breakdown in insulin production or its malfunction in the body. So far, many studies have been done on its treatment.
Ebrahim Esfandiari +4 more
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Вестник трансплантологии и искусственных органовThe creation of a cell-engineered pancreatic construct (CEPC) from islets of Langerhans and biocompatible matrix carrier (framework/scaffold), which imitates the native microenvironment of pancreatic tissue, is an approach to the treatment of type I ...
N. V. Baranova +6 more
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Metabolic Stress Shifts the Function of KCa3.1 Channels in Pancreatic Beta Cells From a Regulator of Membrane Potential to a Proapoptotic Factor [PDF]
Arch Pharm (Weinheim)KATP and KCa3.1 channels are the main components of the regulatory K+ current “Kslow” of pancreatic beta cells. In a diabetogenic environment, the KCa3.1 component of Kslow decreases, and the channel is dysregulated. A targeted pharmacological approach reveals that KCa3.1 channels are functional in mitochondria.
Hense J +4 more
europepmc +2 more sources
Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas AirlanggaIntroduction: Calorie consumption that exceeds normal limits each year can be a risk factor in causing diabetes mellitus (DM). This condition causes the body to be in a state of hyperglycemia, which will trigger changes in the diameter and number of ...
Eny Wulan Sari +3 more
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Collection of islets of Langerhans using an equilibrium method
BioTechniques, 2013 Here we present a convenient method for easy hand selection of enzymatically isolated small tissues such as islets of Langerhans. Islets are continuously collected in a micropipette tip connected to a peristaltic pump.
Duk-Su Koh, Mark Moody, Junghyo Jo
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The effect of ghrelin on Kiss-1 and KissR gene transcription and insulin secretion in rat islets of Langerhans and CRI-D2 cell line [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. The central effects including GH secretion, food intake, and energy homeostasis are partly mediated by Kiss1- KissR signaling pathway. Ghrelin
Mandana Mahmoodzaeh Sagheb +2 more
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