Results 51 to 60 of about 24,397 (218)

Lesió i protecció de les cèl·lules beta en el trasplantament d'illots pancreàtics [PDF]

, 2007
[cat] El trasplantament d'illots pancreàtics pot ser una bona teràpia per els malalts amb diabetis mellitus de tipus 1, però hi ha alguns problemes que cal solventar abans que sigui un tractament estès.
Montolio Rusiñol, Marta
core  

Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding

Molecular Metabolism, 2022
Objective: Identifying the transcripts which mediate genetic association signals for type 2 diabetes (T2D) is critical to understand disease mechanisms. Studies in pancreatic islets support the transcription factor ZMIZ1 as a transcript underlying a T2D ...
Tamadher A. Alghamdi, Nicole A.J. Krentz, Nancy Smith, Aliya F. Spigelman, Varsha Rajesh, Alokkumar Jha, Mourad Ferdaoussi, Kunimasa Suzuki, Jing Yang, Jocelyn E. Manning Fox, Han Sun, Zijie Sun, Anna L. Gloyn, Patrick E. MacDonald   +13 more
doaj   +1 more source

Low‐frequency electroacupuncture attenuates insulin resistance in a rat model of diet‐induced maternal obesity

Pregnancy, Volume 2, Issue 4, July 2026.
Abstract Introduction Maternal obesity is highly prevalent worldwide, conferring elevated risks of maternal/fetal complications and adult‐onset disease in offspring. Obesity and pregnancy are both states of insulin resistance. Percutaneous electrical stimulation of skeletal muscle, better known as electroacupuncture (EA), mitigates insulin resistance ...
David J. Carr, Elizabeth Kelley, Morgan Sekhon, Megan Kawasaki, Keara McElroy‐Yaggy, R. Chris Skinner, Paul D. Taylor, Anna L. David, Elisabet Stener‐Victorin, Thomas L. Jetton   +9 more
wiley   +1 more source

Classification of microscopy images of Langerhans islets

, 2014
Evaluation of images of Langerhans islets is a crucial procedure for planning an islet transplantation, which is a promising diabetes treatment. This paper deals with segmentation of microscopy images of Langerhans islets and evaluation of islet ...
Habart, David, David Habart, Zuzana Berková, Peter Girman, Berková, Zuzana, Girman, Peter, Klára Zacharovová, Jan Švihlík, Zacharovová, Klára, Kříž, Jan, Jan Kybic, Jan Kříž, Kybic, Jan, Švihlík, Jan   +13 more
core   +1 more source

Moderate Intensity of Physical Exercise increased Β (Beta) Cell and Size of Langerhans Islets in Streptozotocin Induced Diabetes Mellitus Rats

Surabaya Physical Medicine and Rehabilitation Journal, 2019
Background: The death of β cells Langerhans islets in Diabetes Mellitus (DM) can cause loss of Langerhans islet function and worsen the progression of DM. Physical exercise plays a major part in DM treatment.
Sarah M Nurdin, Sri Mardjiati Mei Wulan, Nuniek Nugraheni   +2 more
doaj  

IAPP/amylin deposition, which is correlated with expressions of ASC and IL-1β in β-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation

International Journal of Immunopathology and Pharmacology, 2018
Recent findings revealed that type 2 diabetes mellitus (T2D) is a chronic inflammatory disease and an islet amyloid polypeptide (IAPP)/amylin, is deposited within pancreatic islets.
Shinnosuke Morikawa, Naoe Kaneko, Chikara Okumura, Haruka Taguchi, Mie Kurata, Toshihiro Yamamoto, Haruhiko Osawa, Ayaka Nakanishi, Tamotsu Zako, Junya Masumoto   +9 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, Volume 600, Issue 12, Page 1729-1743, June 2026.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

The Effects Of Simvastatin On Islets Of Langerhans In The Pancreas Of Rats: A Histological And Biochemical Study

Journal of Rawalpindi Medical College
Objective: This study explored the effect of simvastatin on the histomorphology of islets of Langerhans, glucose and insulin levels in rats. Study Design: The study was a one-year laboratory-based experimental control trial.
Abdullah Qamar, Hammad Gul Khan, Hina Kundi, Ayesha Ali, Sumyyia Bashir, Tooba Khurshid   +5 more
doaj   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Microwell scaffolds for the extrahepatic transplantation of islets of langerhans [PDF]

, 2013
Allogeneic islet transplantation into the liver has the potential to restore normoglycemia in patients with type 1 diabetes. However, the suboptimal microenvironment for islets in the liver is likely to be involved in the progressive islet dysfunction ...
Engelse, M.A., Apeldoorn, A. van, Ten Hoopen, H.W., Marten A Engelse, Eelco Jp de Koning, Marcel Karperien, Aart A. van Apeldoorn (416714), Roman Truckenmüller (416711), Mijke Buitinga (416710), de Koning, Eelco J.P., Marcel Karperien (119427), Moroni, Lorenzo, Engelse, Marten A., Hetty W. M. Ten Hoopen (416712), Koning, E. de, Mijke Buitinga, Truckenmüller, Roman, Clemens A. van Blitterswijk (270909), Karperien, Marcel; id_orcid, Blitterswijk, C.A. van, Karperien, M., de Koning, E.J., Marten A. Engelse (102782), van Blitterswijk, C.A., Roman Truckenmüller, Lorenzo Moroni (270903), Lorenzo Moroni, Buitinga, Mijke, Eelco JP. de Koning (416713), Apeldoorn, A.A. van, ten Hoopen, Hetty W.M., van Apeldoorn, Aart A., Hoopen, H.W.M. ten, Truckenmuller, R., Aart A van Apeldoorn, van Apeldoorn, A.A., Hetty W M Ten Hoopen, Engelse, M., Buitinga, M., Clemens A van Blitterswijk, Koning, E.J.P. de, Moroni, L., van Blitterswijk, Clemens A., Karperien, Marcel   +43 more
core   +1 more source