Results 71 to 80 of about 24,397 (218)

Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose

, 2007
The present study was undertaken to determine the main metabolic secretory signals generated by the mitochondrial substrate MeS (methyl succinate) compared with glucose in mouse and rat islets and to understand the differences.
Schultz, Vera, Deeney, Jude T., Corkey, Richard F., Shirihai, Orian, Yaney, Gordon C., Luc, Esthere, Corkey, Barbara E., Liu, Lihan, Heart, Emma, Smith, Peter J.S., Tornheim, Keith   +10 more
core   +1 more source

Development of the Islets of Langerhans in Man [PDF]

Nature, 1961
VERY little has been published about the differentiation of the α and β cells in the development of the pancreatic islets in man. The only work since the introduction of the modern granule stains is that of Ferner and Stoeckenius1 (based on twelve fœtal pancreases), and Schultze Jena2 (based on six ...
openaire   +2 more sources

Morphological Features of Tyrosine Hydroxylase Immunoreactive Cells in the Mouse Islets of Langerhans

, 2012
The current immunohistochemical study used the antibody against tyrosine hydroxylase (TH) to observe the immunoreactive elements in the mouse pancreas. The results indicated the presence of immunoreactive nerve fibers and endocrine cells.
Gesase, AP, Satoh, Y-I
core   +1 more source

Studi Mikroanatomi Pankreas Kodok Lembu Menggunakan Metode Pewarnaan Baku dan Immunohistokimia (MICROSCOPICAL STUDY OF PANCREAS OF BULLFROG USING CONVENTIONAL AND IMMUNOSTAINING METHODS)

Jurnal Veteriner, 2012
Morphology, distribution and relative frequency of endocrine cells in the pancreas Bullfrog (Ranacatesbeiana) were studied using conventional and immunohistochemical methods.
I Ketut Mudite Adnyane, Supratikno ., Adi Winarto, Srihadi Agungpriyono   +3 more
doaj  

ChREBP drives β‐cell proliferation under metabolic stress but not in pregnancy‐induced β‐cell expansion

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 938-950, June 2026.
ChREBP is a context‐dependent regulator of adaptive β‐cell proliferation. It plays a pivotal role in driving β‐cell expansion under pathophysiological metabolic stress, such as insulin resistance and hyperglycemia, but has a limited role during physiological expansion in pregnancy.
Sodai Kubota, Seiya Banno, Katsumi Iizuka, Hiromi Tsuchida, Saki Kubota‐Okamoto, Teruaki Sakurai, Yoshihiro Takahashi, Toshinori Imaizumi, Takehiro Kato, Yukio Horikawa, Shin Tsunekawa, Ryota Usui, Hisato Tatsuoka, Shinsuke Tokumoto, Takaaki Murakami, Yuuka Fujiwara, Hitoshi Kuwata, Yuji Yamazaki, Yuichiro Yamada, Yutaka Seino, Daisuke Yabe   +20 more
wiley   +1 more source

Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus

, 2004
The cells within the intact islet of Langerhans function as a metabolic syncytium, secreting insulin in a coordinated and oscillatory manner in response to external fuel.
Barry, D.T., Shirihai, O.S., Messerli, M.A., Harel, T., Katzman, S.M., Chenault, V.M., Smith, P.J.S., Grossman, A.   +7 more
core  

Automated Analysis of Microscopic Images of Isolated Pancreatic Islets

, 2016
Clinical islet transplantation programs rely on the capacities of individual centers to quantify isolated islets. Current computer-assisted methods require input from human operators.
Kříž J., Papáčková Z., Cahová M., Habart D., Saudek F., Berková Z., Fabryová E., Kybic J., Girman P., Kosinová L., Zacharovová K., Schier J., Švihlík J.   +12 more
core   +1 more source

Antidiabetic effect of honey feeding in noise induced hyperglycemic rat: involvement of oxidative stress [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s):In this study the effect of oral administration of honey on serum glucose, lipids, stress oxidative markers, and morphology of langerhans islets in noise induced hyperglycemic rats was investigated.
Saiedeh Arabmoazzen, Alireza Sarkaki, Ghasem saki, Mohammad Ali Mirshekar   +3 more
doaj  

Morphological analysis of isolated rat pancreatic islets cultured under standard culture technique and with biopolymer microstructured collagen‑containing hydrogel

Вестник трансплантологии и искусственных органов, 2017
Introduction. Extracellular matrix play an essential role in providing structural integrity and physiological support to Langerhans islets in pancreas. Imitation of the native microenvironment can be useful for viability of isolated pancreatic islets in ...
L. A. Kirsanova, N. V. Baranova, G. N. Bubentsova, V. I. Sevastianov   +3 more
doaj   +1 more source

Therapeutic Potential of Origanum majorana L. Essential Oil in Diabetes Mellitus: Insights From GC–MS Characterization, In Vivo Hypoglycaemic Studies, and In Silico Analyses

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Exploring the chemical profile and biological property of O. majorana EO. ABSTRACT Diabetes mellitus is a widespread metabolic disorder characterized by impaired glucose regulation. This study investigated the chemical composition and antidiabetic potential of Origanum majorana essential oil (EO) using integrated in vitro, in vivo, and computational ...
Mahmoud Houas, Mohammed Larbi Benamor, Elhafnaoui Lanez, Yahia Bekkar, Lotfi Bourougaa, Ouafa Boudebia, Rania Bouraoui, Aicha Adaika, Nafila Zouaghi, Salah Neghmouche Nacer, Lazhar Bechki, Touhami Lanez, Stefania Garzoli   +12 more
wiley   +1 more source