Results 71 to 80 of about 167,453,715 (202)
In Vivo Imaging of Transplanted Pancreatic Islets
The beta-cells in the islets of Langerhans in the pancreas secrete insulin and play an important role in glucose homeostasis. Diabetes, characterized by hyperglycemia, results from an absolute or a relative deficiency of the pancreatic beta-cell mass ...
Donghee Kim +3 more
doaj +1 more source
Abstract The most common treatment for people with people with type 1 diabetes (T1D) requires injections of exogenous insulin to regulate blood glucose homeostasis. A longer‐term therapeutic solution for T1D has emerged whereby patients may regain insulin independence through transplantation of donated human pancreatic islets, which contain insulin ...
Manuj Bandral +2 more
wiley +1 more source
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani +4 more
wiley +1 more source
Morphology, distribution and relative frequency of endocrine cells in the pancreas Bullfrog (Ranacatesbeiana) were studied using conventional and immunohistochemical methods.
I Ketut Mudite Adnyane +3 more
doaj
HAR may improve T2DM by enhancing antioxidant defences through Nrf2 activation while suppressing inflammation and RAS activity, supporting its capability to treat diabetes. ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation.
Farima Malekinia +5 more
wiley +1 more source
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
Abstract Glucagon is a well‐established therapeutic peptide, widely used to treat hypoglycemia. Like many peptide drugs, it offers advantages such as specificity, biocompatibility, and high affinity for receptor targets, but suffers from limited physical and chemical stability.
Angelo Santoro +4 more
wiley +1 more source
VARIATION IN THE AREA OF ISLETS OF LANGERHANS IN SODIUM CYCLAMATE TREATED RATS
Objective: To observe the effects of sodium cyclamate on islets of langerhans in rats pancreas. Study Design: Laboratory based randomized control trial. Duration of study: Anatomy Department, Army Medical College Rawalpindi, in collaboration with
Hina Kundi +2 more
doaj +2 more sources
The Endothelial Cells in Islets of Langerhans [PDF]
The blood vessels of the pancreatic islets are of crucial importance for oxygen and metabolite supply, and dispersal of secreted hormones. In addition to this, endothelial cells have an important role in the revascularization process after islet transplantation.
openaire +2 more sources
Antidiabetic effect of honey feeding in noise induced hyperglycemic rat: involvement of oxidative stress [PDF]
Objective(s):In this study the effect of oral administration of honey on serum glucose, lipids, stress oxidative markers, and morphology of langerhans islets in noise induced hyperglycemic rats was investigated.
Saiedeh Arabmoazzen +3 more
doaj

