Results 81 to 90 of about 24,397 (218)

Constitutive nitric oxide synthase (cNOS) activity in Langerhans islets from streptozotocin diabetic rats

Brazilian Journal of Medical and Biological Research, 1998
Nitric oxide synthase activity was measured in Langerhans islets isolated from control and streptozotocin diabetic rats. The activity of the enzyme was linear up to 150 µg of protein from control rats and was optimal at 0.1 µM calcium, when it was ...
T.M. Fonovich de Schroeder, M.D. Carattino, M. Frontera, O.L. Catanzaro   +3 more
doaj   +1 more source

Pancreatic islet (of Langerhans) revisited.

Histology and histopathology, 2019
One hundred and fifty years ago, Paul Langerhans described what would come to be known as pancreatic 'islet of Langerhans'. Since then, we have accumulated knowledge about the pancreatic islet, the cells that exist there and the hormones secreted by these cells.
openaire   +3 more sources

Excitation wave propagation as a possible mechanism for signal transmission in pancreatic islets of Langerhans

, 2001
In response to glucose application, β-cells forming pancreatic islets of Langerhans start bursting oscillations of the membrane potential and intracellular calcium concentration, inducing insulin secretion by the cells.
Mornev, Oleg A., Scott, Alwyn C., Christiansen, Peter L., Mornev, O A, Christiansen, Peter Leth, Skyggebjerg, O, Skyggebjerg, Ole, Thastrup, O, Conradsen, Knut, Thastrup, O., Arkhammar, Per, Sørensen, Mads Peter, Arkhammar, P, Christiansen, P L, Aslanidi, O V, Scott, A C, Sørensen, M P, Aslanidi, Oleg V., Sørensen, Mads P., Conradsen, K, Thastrup, Ole   +20 more
core   +1 more source

Antidiabetic effects of fennel leaf aqueous extract in alloxan-induced diabetic rats

Journal of Pharmaceutical Health Care and Sciences
Background Diabetes Mellitus is a common chronic metabolic disease in the world population. There is evidences on the anti-hyperglycemic effects of different parts of fennel; however, the reports about antidiabetic activity of fennel leaves are not ...
Mahdi Noureddini, Maryam Akbari, Zeinab Vahidinia, Samaneh Sadat Alavi, Majid Nejati, Mohammad Ali Atlasi   +5 more
doaj   +1 more source

Metabolism of Glucose in the Islets of Langerhans

Journal of Biological Chemistry, 1968
Abstract The levels of glycogen, glucose, glucose-6-P, the sum of fructose diphosphate plus dihydroxyacetone-P, ATP, and the pyridine nucleotides were measured in endocrine and exocrine tissue of the pancreas of obese hyperglycemic mice. Sorbitol was determined in both types of tissue after a single intravenous injection of the compound.
Matschinsky, F M, Ellerman, J E
openaire   +2 more sources

Prediction of Pancreatic Islet Yield After Pancreatectomy Using Optical Coherence Elastography

Diagnostics
Intraoperative assessment of pancreatic quality, followed by sampling for the potential isolation of Langerhans islets for subsequent autotransplantation, is currently a key component of post-total pancreatectomy diabetes mellitus treatment.
Ekaterina Gubarkova, Ekaterina Vasilchikova, Arseniy Potapov, Denis Kuchin, Polina Ermakova, Julia Tselousova, Anastasia Anina, Liya Lugovaya, Marina Sirotkina, Natalia Gladkova, Aleksandra Kashina, Vladimir Zagainov   +11 more
doaj   +1 more source

Functional abnormalities of islets of Langerhans of obese hyperglycemic mouse.

, 1977
Glucose-induced insulin release was studied in vitro with isolated islets of Langerhans obtained from obese hyperglycemic C57Bl/6J-ob/ob (ob/ob) and lean C57Bl/6J-+/+ (control) mice.
L Recant, R L Lavine, N Voyles, P V Perrino   +3 more
core   +1 more source

Adventures with Insulin in the Islets of Langerhans [PDF]

Journal of Biological Chemistry, 2011
Insulin is a small but beautifully organized protein with a unique two-chain structure, the first protein to be sequenced. The mechanism of its biosynthesis invited much initial speculation but was finally clarified by the discovery of proinsulin, its single-chain precursor.
openaire   +2 more sources

Immobilization of Sertoli cells on islets of Langerhans

, 2013
Sertoli cells play a crucial role in creating the immunoprivileged environment of the testis. We examined the survival of islets of Langerhans after co-transplantation with Sertoli cells. Sertoli cells near islets should protect the graft from rejection.
Takemoto, Naohiro, Teramura, Yuji,, Iwata, Hiroo   +2 more
core   +1 more source

Adenomatosis of the Islets of Langerhans [PDF]

BMJ, 1955
E R, BICKERSTAFF, O G, DODGE, A, GOUREVITCH, G W, HEARN   +3 more
openaire   +2 more sources