Results 21 to 30 of about 167,453,715 (202)

Islets of Langerhans Are Protected from Inflammatory Cell Recruitment during Reperfusion of Rat Pancreas Grafts [PDF]

, 2010
Background: Ischemia/reperfusion (I/R) injury plays a pivotal role in the development of graft pancreatitis, with ischemia time representing one of its crucial factors.
Winter, H., Waldner, H., Löhe, F., Eichhorn, M. E., Massberg, S., Preissler, G., Messmer, K., Preissler, G.;Massberg, S.;Eichhorn, M. E.;Waldner, H.;Loehe, F.;Winter, H.;Messmer, K.   +7 more
core   +1 more source

Perfusion-Based Recellularization of Rat Livers with Islets of Langerhans [PDF]

, 2022
Purpose: Artificial organs might serve as alternative solutions for whole organ transplantation. Decellularization of a liver provides a non-immunogenic matrix with the advantage of three afferent systems, the portal vein, the hepatic artery and the bile
Polenz, Dietrich, Raschzok, Nathanael, Napierala, Hendrik, Sauer, Igor M., Pratschke, Johann, Hillebrandt, Karl H., Struecker, Benjamin, Dobrindt, Eva M., Tang, Peter, Kluge, Martin, Demko, Peter, Haep, Nils, Gassner, Joseph M. G. V., Reutzel-Selke, Anja, Everwien, Hannah   +14 more
core   +1 more source

Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

Stem Cell Research & Therapy, 2017
Background Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets.
Elisa Montanari, Raphael P. H. Meier, Redouan Mahou, Jörg D. Seebach, Christine Wandrey, Sandrine Gerber-Lemaire, Leo H. Buhler, Carmen Gonelle-Gispert   +7 more
doaj   +1 more source

Transplante isogênico de ilhotas de Langerhans no fígado de ratos: metodologia para separação e purificação das ilhotas de Langerhans Isogenic islet transplantation on the rat liver: Method for isolation and purification of the rat islets

Arquivos de Gastroenterologia, 2000
A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina mantendo os níveis glicêmicos dentro da normalidade.
Eleazar CHAIB, Apostolos PAPALOIS, Ingrid G. M. BRONS, Roy Y. CALNE   +3 more
doaj   +1 more source

Insulin Treatment of Mice Recipients Preserves β-Cell Function in Porcine Islet Transplantation

Cell Transplantation, 2002
Encapsulation of islets of Langerhans confers protection against cell-mediated immune destruction and so should allow the transplantation of islets without immunosuppression.
Oleg Pakhomov, Jiry Honiger, Edouard Gouin, Roland Cariolet, Gerard Reach, Sylviane Darquy Ph.D.   +5 more
doaj   +1 more source

The pancreatic islet: a micro-organ in control [PDF]

CellR4, 2021
The islets of Langerhans constitute the endocrine pancreas which regulates blood glucose homeostasis and islet dysfunction results in diabetes. Each of the pancreatic islets constitutes an entire micro-organ with intricate cell to cell interactions and ...
M. Abdulreda, P. Berggren
doaj   +1 more source

The Islets of Langerhans in Relation to Diabetes [PDF]

Biochemical Journal, 1907
The work recorded in the following paper was undertaken with a view to testing the hypothesis frequently brought forward that the islets of Langerhans of the pancreas yield an internal secretion whose function has some relation to the utilization of dextrose in the vertebrate organism. The primary cause of diabetes is, according to Macleod,1 the ' want
J, Rennie, T, Fraser
openaire   +2 more sources

Isolation and Purification of Rodent Pancreatic Islets 2 of Langerhans [PDF]

, 2020
This chapter describes the detailed protocol for the isolation and purification of islets of Langerhans from 6 AU1 rodent pancreas using collagenase digestion.
Stocker, Claire J., O'Dowd, Jacqueline F.   +1 more
core   +1 more source

HISTOMORPHOLOGICAL PECULIARITIES OF THE PANCREATIC PARENCHYMA IN RATS WITH ALLOXAN-INDUCED DIABETES OF DIFFERENT DURATION

Неонатологія, хірургія та перинатальна медицина
The study of pathohistological and morphofunctional changes in the endocrine pancreas is an integral part of experimental diabetology, which allows obtaining a signifi cant amount of information on various aspects of the etiology and pathogenesis of ...
О. Оленович, Т. Бойчук, І. Давиденко, О. Давиденко   +3 more
doaj   +1 more source

Entrapment of Cultured Pancreas Islets in Three-Dimensional Collagen Matrices

Cell Transplantation, 1992
In vitro culture of islets of Langerhans decreases their immunogenecity, presumably by eliminating passenger leukocytes and other Ia+ presenting cells within the islets.
Seh-Huang Chao, Madhusudan V. Peshwa, David E.R. Sutherland M.D., Ph.D., Wei-Shou Hu   +3 more
doaj   +1 more source