Results 21 to 30 of about 24,397 (218)

Islets of Langerhans Are Protected from Inflammatory Cell Recruitment during Reperfusion of Rat Pancreas Grafts [PDF]

, 2010
Background: Ischemia/reperfusion (I/R) injury plays a pivotal role in the development of graft pancreatitis, with ischemia time representing one of its crucial factors.
Winter, H., Waldner, H., Löhe, F., Eichhorn, M. E., Massberg, S., Preissler, G., Messmer, K.   +6 more
core   +1 more source

Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

Stem Cell Research & Therapy, 2017
Background Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets.
Elisa Montanari, Raphael P. H. Meier, Redouan Mahou, Jörg D. Seebach, Christine Wandrey, Sandrine Gerber-Lemaire, Leo H. Buhler, Carmen Gonelle-Gispert   +7 more
doaj   +1 more source

Transplante isogênico de ilhotas de Langerhans no fígado de ratos: metodologia para separação e purificação das ilhotas de Langerhans Isogenic islet transplantation on the rat liver: Method for isolation and purification of the rat islets

Arquivos de Gastroenterologia, 2000
A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina mantendo os níveis glicêmicos dentro da normalidade.
Eleazar CHAIB, Apostolos PAPALOIS, Ingrid G. M. BRONS, Roy Y. CALNE   +3 more
doaj   +1 more source

The pancreatic islet: a micro-organ in control [PDF]

CellR4, 2021
The islets of Langerhans constitute the endocrine pancreas which regulates blood glucose homeostasis and islet dysfunction results in diabetes. Each of the pancreatic islets constitutes an entire micro-organ with intricate cell to cell interactions and ...
M. Abdulreda, P. Berggren
doaj   +1 more source

Preganglionic innervation of the pancreas islet cells in the rat [PDF]

, 1984
The position and number of preganglionic somata innervating the insulin-secreting β-cells of the endocrine pancreas were investigated in Wistar rats.
Steffens, A.B.,, Luiten, P. G. M., TERHORST, GJ, Koopmans, S. J., Koopmans, S.J.,, Luiten, P.G.M.,, ter Horst, G. J., Rietberg, M., KOOPMANS, SJ, LUITEN, PGM, Horst, G.J. ter,, Rietberg, M.,, RIETBERG, M, STEFFENS, AB, Steffens, A. B.   +14 more
core   +1 more source

human Langerhans Islets data

, 2023
Human Langerhans Islets data used to train a machine learning algorithm able to classify beta and alpha cells. Static autofluoresnce and FLIM data are stored in R64 files (either single-cell segmented or not) and immunosfluorescence data are present as ...
Fabio Azzarello (16390695), Valentina De Lorenzi (16668467), Francesco Cardarelli (16390704)   +2 more
core   +1 more source

Insulin Treatment of Mice Recipients Preserves β-Cell Function in Porcine Islet Transplantation

Cell Transplantation, 2002
Encapsulation of islets of Langerhans confers protection against cell-mediated immune destruction and so should allow the transplantation of islets without immunosuppression.
Oleg Pakhomov, Jiry Honiger, Edouard Gouin, Roland Cariolet, Gerard Reach, Sylviane Darquy Ph.D.   +5 more
doaj   +1 more source

Crocin Protects Mice Pancreatic Islets from Oxidative Stress Induced by Methylglyoxal and Increases Insulin Secretion

Düzce Tıp Fakültesi Dergisi, 2023
Aim: Islets of Langerhans are more sensitive to oxidative damage because of their low antioxidant capacity. In diabetes, methylglyoxal (MG) accumulates in the pancreas.
Akram Ahangarpour, Reza Noeı Razlıqı, Elnaz Haroonı, Vahid Radmehr   +3 more
doaj   +1 more source

Laser Capture Microdissection Coupled Capillary Immunoassay to Study the Expression of PCK-2 on Spatially-Resolved Islets of Rat Langerhans

Pharmaceutics, 2021
The platform for precise proteomic profiling of targeted cell populations from heterogeneous tissue sections is developed. We demonstrate a seamless and systematic integration of LCM with an automated cap-IA for the handling of a very small-sized ...
Shashank Pandey, Zdenek Tuma, Tereza Smrhova, Miroslava Cedikova, Tereza Macanova, Magdalena Chottova Dvorakova   +5 more
doaj   +1 more source

The Histological Changes in Endocrine Part of the Pancreas of Diabetic Rats Treated with Rosa Damascena Extract

مجله دانشکده پزشکی اصفهان, 2020
Background: Diabetes is caused by a breakdown in insulin production or its malfunction in the body. So far, many studies have been done on its treatment.
Ebrahim Esfandiari, Shima Rouhollahi, Sayed Mostafa Ghanadian, Bahman Rashidi, Fatemeh Sadat Sadat Mostafavi   +4 more
doaj   +1 more source