Azelaic acid reduces arsenic-induced toxicity and inflammation in the rat islets of langerhans [PDF]
Objective(s): Arsenic is classified as a toxic metal that is naturally found in the Earth’s crust, and long-term exposure to it can result in chronic human disorders like cancer and diabetes.
Sara Mostafalou +4 more
doaj +2 more sources
Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment [PDF]
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani +7 more
wiley +2 more sources
A Tissue-Engineered Construct Based on a Decellularized Scaffold and the Islets of Langerhans: A Streptozotocin-Induced Diabetic Model [PDF]
Producing a tissue-engineered pancreas based on a tissue-specific scaffold from a decellularized pancreas, imitating the natural pancreatic tissue microenvironment and the islets of Langerhans, is one of the approaches to treating patients with type 1 ...
Victor I. Sevastianov +12 more
doaj +2 more sources
Potential of [11C]UCB-J as a PET tracer for islets of Langerhans [PDF]
Biomarkers for the measurement of islets of Langerhans could help elucidate the etiology of diabetes. Synaptic vesicle glycoprotein 2 A (SV2A) is a potential marker reported to be localized in the endocrine pancreas.
Emmi Puuvuori +5 more
doaj +2 more sources
Antioxidant Effects of Eugenol on Oxidative Stress Induced by Hydrogen Peroxide in Islets of Langerhans Isolated from Male Mouse [PDF]
Background. The antioxidant system in islets of Langerhans is weak, which can lead to diabetes. Meanwhile, the main component of cloves that produce antioxidant effects is eugenol.
Ali Akbar Oroojan +2 more
doaj +2 more sources
Reinnervation of Isolated Islets of Langerhans Transplanted beneath the Kidney Capsule in the Rat
Neural regulation of islets of Langerhans mediates responses to stress and food ingestion. Transplantation of isolated islets offers hope to patients with insulin dependent diabetes mellitus but denervation of isolated islets may affect the capacity for ...
Andrew J. Portis +2 more
doaj +2 more sources
Perfusion-Based Recellularization of Rat Livers with Islets of Langerhans [PDF]
Purpose: Artificial organs might serve as alternative solutions for whole organ transplantation. Decellularization of a liver provides a non-immunogenic matrix with the advantage of three afferent systems, the portal vein, the hepatic artery and the bile
Polenz, Dietrich +14 more
core +1 more source
A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of Langerhans [PDF]
Background: The extracellular calcium-sensing receptor (CaR) is expressed in many tissues that are not associated with Ca2+ homeostasis, including the endocrine cells in pancreatic islets of Langerhans.
Persaud, Shanta J.; id_orcid +6 more
core +1 more source
Noradrenergic and Cholinergic Reinnervation of Islet Grafts in Diabetic Rats [PDF]
Grafted islets become denervated due to the islet transplantation procedure. The aim of the present study was 1) to examine whether islet grafts in the liver, the spleen, and under the kidney capsule in rats become reinnervated following the ...
Oestreicher, AB +27 more
core +1 more source
Isolation and Purification of Rodent Pancreatic Islets 2 of Langerhans [PDF]
This chapter describes the detailed protocol for the isolation and purification of islets of Langerhans from 6 AU1 rodent pancreas using collagenase digestion.
Stocker, Claire J. +1 more
core +1 more source

