Results 191 to 200 of about 869,856 (392)

Automatic bio-sample bacteria detection system [PDF]

open access: yes, 1971
Electromechanical device analyzes urine specimens in 15 minutes and processes one sample per minute. Instrument utilizes bioluminescent reaction between luciferase-luciferin mixture and adenosine triphosphate (ATP) to determine number of bacteria present
Chappelle, E. W.   +3 more
core   +1 more source

From Code to Life: The AI‐Driven Revolution in Genome Editing

open access: yesAdvanced Science, EarlyView.
This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li   +10 more
wiley   +1 more source

Improved methods for counting bacteria in physiological fluids [PDF]

open access: yes, 1974
Bacterial population detection is based on detection of adenosine triphosphate (ATP), chemical present in all living matter. Amount of ATP in sample, after chemically removing all nonbacterial ATP, is directly related to bacterial population. Sensitivity
Picciolo, G. L.
core   +1 more source

Rictor Ameliorates Acute Antibody‐Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65‐NLRP3 Axis

open access: yesAdvanced Science, EarlyView.
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni   +12 more
wiley   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

open access: yesAdvanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu   +16 more
wiley   +1 more source

Energy Homeostasis of the Artificial Bladder in Experimental Conditions [PDF]

open access: yes, 2018
Patients with Malignant neoplasms of the bladder or severe anatomical and functional bladder abnormalities are the candidates for cystectomy and orthotopic urine diversion.
Dekhtiar, Y. (Yriy)   +3 more
core  

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

open access: yesScience, 2008
Veli-Pekka Jaakola   +7 more
semanticscholar   +1 more source

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