Results 231 to 240 of about 617,017 (357)

Cilostazol Conduction Effects: A Possible Adjunctive Therapy Option? [PDF]

JACC Case Rep
Haloot J, Birnbaum Y.
europepmc   +1 more source

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

Advanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang, Jingxuan Wang, Kerong Tu, Xiaobing Huang, Liangliang Lv, Mingjie Peng, Qiqi Xu, Hongmei Liu, Qiang Sun, Lulu Cai   +9 more
wiley   +1 more source

Functional significance of adenosine in carotid body chemosensory activity in control and chronically hypoxic animals

, 2007
Sílvia V. Conde
openalex   +1 more source

A unified framework combining linear and 3D molecular features for robust drug-protein interaction prediction. [PDF]

Cell Rep Methods
Sun C, Qin Z, Li M, Li Y, Tang R, Chen S, Wang Y, Liu Y, Wei J, Liu J.   +9 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Evaluation of adenosine deaminase/CD26 pathway in the proliferation and esophageal cancer progression

, 2022
Laisa Helena Silva Silveira
openalex   +1 more source

Adenosine Triggers an ADK-Dependent Intracellular Signaling Pathway Interacts PFKFB3-Mediated Glycolytic Metabolism to Promote Newly Formed Myofibers Development. [PDF]

Int J Mol Sci
Wu X, Zeng D, Wang B, Liu J, Zhang Y, Huang C, Nie Q, Shi L, Wang Y.   +8 more
europepmc   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source

The Study of Chinese Herbal Medicinal Prescription with Enzyme Inhibitory Activity. VI. The Study of Makyo-kanseki-to with Adenosine 3', 5'-Cyclic Monophosphate Phosphodiesterase

, 1992
Tamotsu NIKAIDO, Setsuko IIZUKA, Noriko OKADA, Takashi Kuge, Taichi OHMOTO   +4 more
openalex   +2 more sources