Results 1 to 10 of about 54,436 (239)

Deficiency of Adenosine Deaminase 2 [PDF]

Turkish Journal of Hematology
Adenosine deaminase 2 (ADA2) deficiency is an autosomal recessively inherited autoinflammatory disorder caused by loss-of-function mutations in the ADA2 gene. Although the pathogenesis involves the triggering of a proinflammatory cascade due to increased
Çağrı Coşkun, Şule Ünal
doaj   +2 more sources

Adenosine deaminase deficiency: a review [PDF]

Orphanet Journal of Rare Diseases, 2018
Adenosine deaminase (ADA) deficiency leads to an accumulation of toxic purine degradation by-products, most potently affecting lymphocytes, leading to adenosine deaminase-deficient severe combined immunodeficiency.
Aisling M. Flinn, Andrew R. Gennery
doaj   +3 more sources

Adenosine deaminase acting on RNA 1 (ADAR1) as crucial regulators in cardiovascular diseases: structures, pathogenesis, and potential therapeutic approach

Frontiers in Pharmacology, 2023
Cardiovascular diseases (CVDs) are a group of diseases that have a major impact on global health and are the leading cause of death. A large number of chemical base modifications in ribonucleic acid (RNA) are associated with cardiovascular diseases.
Jieying Chen, Junyan Jin, Junyan Jin, Jun Jiang, Jun Jiang, Yaping Wang, Yaping Wang   +6 more
doaj   +1 more source

Serum Adenosine Deaminase as a Useful Marker to Estimate Coronary Artery Calcification in Type 2 Diabetes Mellitus Patients

Clinical and Applied Thrombosis/Hemostasis, 2021
We investigated the association between serum adenosine deaminase and coronary artery calcification (CAC) in type 2 diabetes mellitus (T2DM) patients.
Ming Yu M.Med, Hanyun Zhou M.Med, Qingan Li MB, Juan Ding MB, Hongxia Shuai PhD, Ji Zhang MB   +5 more
doaj   +1 more source

Adenosine deaminase as a marker for the severity of infectious mononucleosis secondary to EBV in children

BMC Infectious Diseases, 2022
Background Infectious mononucleosis, a common disease in children and young adults, is often accompanied by elevated transaminase levels and rarely, liver failure.
Ting Shi, Jungen Li, Yuzhu Miao, Linlin Huang, Jianmei Tian   +4 more
doaj   +1 more source

Role of serum and pleural adenosine deaminase activity compared to pleural fluid analysis in patients with pleural effusion of various etiology

MRIMS Journal of Health Sciences, 2023
Background: Numerous tests are available for determining the cause of exudate, but all these tests lack sensitivity and specificity, and they are not generally available.
Mubasheer Ali, Prashant Janjal, M V Raghavendra Rao   +2 more
doaj   +1 more source

In Silico approach for identification, prediction of AMPD1 gene nsSNPs associated with Myoadenylate Deaminase deficiency [PDF]

Journal of Bioscience and Applied Research, 2023
Background: Myoadenylate deaminase deficiency is an autosomal recessive metabolic myopathy caused by mutations in the Adenosine monophosphate deaminase 1 gene.
Abrar Mohamed, Abdelrahman Hamza, Hiba Fadl, Afra Albkrye, Hadeel Ahmed, Hazem Abubaker, Sahar Elbager   +6 more
doaj   +1 more source

Tubercular Pericardial Effusion Presenting as Cardiac Tamponade

Journal of Nepal Health Research Council, 2021
Pericardial effusion is an uncommon extra-pulmonary manifestation of tuberculosis, tamponade being even rarer. Here, a 14-year female presented with cough, chest pain and fever.
Alok Pradhan, Ranjit Babu Jasaraj, Bhesh Raj Karki, Anish Joshi   +3 more
doaj   +1 more source

EFFECT OF SOME ANTIBIOTICS IN ACTIVITY OF ADENOSINE DEAMINASE IN SERUM [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
The aim of this study is to know the effect of same antibiotics such as tetracycline, benzyl pencillin and ampicillin on activity of adenosine deaminase (ADA) level in patients with brucellosis.
WESAM M. MOHAMMED ATEA
doaj   +1 more source

Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates. [PDF]

, 2017
A series of emissive ribonucleoside purine mimics, all comprised of an isothiazolo[4,3-d]pyrimidine core, was prepared using a divergent pathway involving a key Thorpe-Ziegler cyclization.
Fin, Andrea, Rovira, Alexander R, Tor, Yitzhak   +2 more
core   +1 more source