Results 151 to 160 of about 238,585 (333)

Antihyperglycemic, antihyperlipidemic, anti-inflammatory and adenosine deaminase– lowering effects of garlic in patients with type 2 diabetes mellitus with obesity

open access: yesDiabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 2013
Introduction Type 2 diabetes mellitus is a chronic disorder characterized by chronic hyperglycemia, with long term macrovascular and microvascular complications. The treatment is lifestyle management, exercise, weight control, and antihyperglycemic drugs
Rahat Kumar   +7 more
semanticscholar   +1 more source

A Rare Case of Budd–Chiari Syndrome in a Young Female

open access: yesClinical Case Reports, Volume 13, Issue 5, May 2025.
ABSTRACT Budd–Chiari syndrome is a rare disorder characterized by hepatic vein obstruction, with an incidence of 1 in 100,000. It can be diagnosed through imaging studies and initially managed with anticoagulants. Acute Budd–Chiari syndrome can be treated with thrombolysis to dissolve blood clots obstructing hepatic veins.
Joshua Chacko   +5 more
wiley   +1 more source

Adenosine Deaminase Activity in COPD Patients and Healthy Subjects

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2010
Chronic obstructive pulmonary disease (COPD) has been defined by the Global Initiative for Chronic Obstructive Lung Disease (GOLD), as a disease state characterized by airflow limitation which is not fully reversible.
Mohammad Taghi Goodarzi   +4 more
doaj  

Deamination of Adenosine Diphosphate by Adenylate Deaminase Preparations [PDF]

open access: bronze, 1954
Adam Deutsch   +4 more
openalex   +1 more source

Novel Oxadiazole‐Based Bioisostere of Caffeic Acid Phenethyl Ester: Synthesis, Anticancer Activity, and Inhibition of Lipoxygenase Product Biosynthesis

open access: yesDrug Development Research, Volume 86, Issue 3, May 2025.
ABSTRACT Caffeic acid phenethyl ester (1), a honeybee propolis component, possesses many bioactive properties, making it a useful scaffold for drug research. Further, CAPE (1) is a more effective inhibitor of the biosynthesis of 5‐lipoxygenase (5‐LO) products compared to Zileuton, the only clinically‐approved direct 5‐LO inhibitor.
Mika A. Robichaud   +5 more
wiley   +1 more source

Feed-Forward Inhibition of CD73 and Upregulation of Adenosine Deaminase Contribute to the Loss of Adenosine Neuromodulation in Postinflammatory Ileitis

open access: yesMediators of Inflammation, 2014
Purinergic signalling is remarkably plastic during gastrointestinal inflammation. Thus, selective drugs targeting the “purinome” may be helpful for inflammatory gastrointestinal diseases. The myenteric neuromuscular transmission of healthy individuals is
Cátia Vieira   +7 more
doaj   +1 more source

Adenosine Deaminase in Diagnosis of Tuberculosis: A Review

open access: yes, 2014
The diagnosis of tuberculosis (TB) continues to be a challenge in clinical practice. Traditional diagnostic methods are very useful but do not provide enough sensitivity and specificity.
R. Barua, Marufa Hossain
semanticscholar   +1 more source

Soluble Ecto-5′-nucleotidase (5′-NT), Alkaline Phosphatase, and Adenosine Deaminase (ADA1) Activities in Neonatal Blood Favor Elevated Extracellular Adenosine*

open access: yesJournal of Biological Chemistry, 2013
Background: Newborns have elevated plasma adenosine levels, which may influence their immunological function. Results: Compared with adults, newborns have elevated plasma 5′-NT and alkaline phosphatase activities and lower adenosine deaminase activity ...
M. Pettengill   +13 more
semanticscholar   +1 more source

AI‐Assisted Plasmonic Diagnostics Platform for Osteoarthritis and Rheumatoid Arthritis With Biomarker Quantification Using Mathematical Models

open access: yesSmall, Volume 21, Issue 18, May 5, 2025.
A plasmonic diagnostics platform utilizing a highly dense urchin‐like gold nanoarchitecture (UGN) enables rapid, label‐free differentiation of osteoarthritis and rheumatoid arthritis via enhanced Raman signals. Machine learning‐assisted analysis achieves high diagnostic accuracy; while, metabolic biomarker quantification provides insights into ...
Boyou Heo   +9 more
wiley   +1 more source

Evaluation of the adenosine deaminase (ADA) G22A gene polymorphism with recurrent spontaneous abortion among Egyptian patients

open access: yesCentral European Journal of Immunology, 2017
Introduction : Adenosine and deoxyadenosine metabolism is influenced by adenosine deaminase (ADA) enzyme. ADA increases in different diseases and is considered as one of the markers for cell-mediated immunity.
Hanan Mohamed Farhan   +3 more
doaj   +1 more source

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