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The CRISPR-associated adenosine deaminase Cad1 converts ATP to ITP to provide antiviral immunity. [PDF]

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Adenosine deaminase inhibition

International Journal of Biological Macromolecules, 2019
Adenosine deaminase is a critical enzyme in purine metabolism that regulates intra and extracellular adenosine concentrations by converting it to inosine. Adenosine is an important purine that regulates numerous physiological functions by interacting with its receptors.
Bagheri, S., Saboury, A.A., Haertle, T.
openaire   +3 more sources

Adenosine Deaminase Deficiency

Hospital Practice, 1987
Inherited deficiency of the purine salvage enzyme adenosine deaminase (ADA) is responsible for approximately half the cases of autosomal recessive Severe Combined Immunodeficiency (SCID). Deficiency of ADA can also result in a much later-onset, milder immunodeficiency, while lesser degrees of enzyme deficiency can result in either late-onset ...
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Adenosine deaminase inhibitors: Differential effects on multiple forms of adenosine deaminase

Biochemical and Biophysical Research Communications, 1978
Summary Three forms of calf intestine adenosine deaminase were resolved by gel filtrat in Sephacryl C-200 into species of 38,000 (E S ), 57,000 (E I ) and greater than 200,00 (E L ) daltons. The sensitivities of the three forms of adenosine deaminase to the adenosine deaminase inhibitors, 2′-deoxycoformycin (dCF) and erythro-9-(2-hydroxynonyl)adenine
J, Constine, R I, Glazer, D G, Johns
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